Designing anticancer drugs via the achilles heel: ceramide, allylic ketones, and mitochondria (Q35114241)

6 August 2017

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title

Designing anticancer drugs via the achilles heel: ceramide, allylic ketones, and mitochondria (English)

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6 August 2017

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Norman S Radin

1

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PubMed ID

12713822

6 August 2017

language of work or name

English

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publication date

1 May 2003

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Bioorganic & Medicinal Chemistry

6 August 2017

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6 August 2017

11

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6 August 2017

10

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6 August 2017

2123-2142

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Targeting ceramide metabolism--a strategy for overcoming drug resistance

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Killing cancer cells by poly-drug elevation of ceramide levels: a hypothesis whose time has come?

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

1 reference

7 January 2021

Advances in the signal transduction of ceramide and related sphingolipids

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Physiology and pathophysiology of sphingolipid metabolism and signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Sphingolipids--the enigmatic lipid class: biochemistry, physiology, and pathophysiology

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

The role of sphingolipids in the process of signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Positive feedback control of neutral sphingomyelinase activity by ceramide

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Effects of reduced and oxidized glutathione on sphingomyelinase activity and contents of sphingomyelin and lipid peroxidation products in murine liver

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Glutathione depletion causes cell growth inhibition and enhanced apoptosis in pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5-trans-double bond of sphingosine at the level of dihydroceramide

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Ataxia telangiectasia-mutated gene product inhibits DNA damage-induced apoptosis via ceramide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Accumulation of glucosylceramides in multidrug-resistant cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Lactosylceramide mediates shear-induced endothelial superoxide production and intercellular adhesion molecule-1 expression

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Sphingolipids in atherosclerosis and vascular biology

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Gangliosides shed by tumor cells enhance tumor formation in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Inhibition of glycolipid shedding rescues recognition of a CD1+ T cell lymphoma by natural killer T (NKT) cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Dietary sphingolipids in colorectal cancer prevention.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Tamoxifen retards glycosphingolipid metabolism in human cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

cis-4-Methylsphingosine decreases sphingolipid biosynthesis by specifically interfering with serine palmitoyltransferase activity in primary cultured neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Oxidative stress: role of mitochondria and protection by glutathione

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Molecular cloning and characterization of a human mitochondrial ceramidase

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Human acid ceramidase is overexpressed but not mutated in prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Rapid reactive oxygen species production by mitochondria in endothelial cells exposed to tumor necrosis factor-alpha is mediated by ceramide

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Differential insulin-like growth factor (IGF)-independent interactions of IGF binding protein-3 and IGF binding protein-5 on apoptosis in human breast cancer cells. Involvement of the mitochondria.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Direct interaction of GD3 ganglioside with mitochondria generates reactive oxygen species followed by mitochondrial permeability transition, cytochrome c release, and caspase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

GD3 recruits reactive oxygen species to induce cell proliferation and apoptosis in human aortic smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Apoptotic death by ceramide: will the real killer please stand up?

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

A new procedure for synthesis of 3-keto derivatives of sphingolipids and its application for study of fatty acid composition of brain ceramides and cerebrosides containing dihydrosphingosine of sphingosine.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

The antiproliferative effects of biologically active isomers of conjugated linoleic acid on human colorectal and prostatic cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Enantioselective depletion of mitochondrial glutathione concentrations by (S)- and (R)-3-hydroxy-4-pentenoate

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Glutathionyl transferase catalyzed addition of glutathione to COMC: a new hypothesis for antitumor activity

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Occurrence of ceramides and neutral glycolipids with unusual long-chain base composition in purified rat liver mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Synthetic phytoceramides induce apoptosis with higher potency than ceramides.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Phytosphingosine as a specific inhibitor of growth and nutrient import in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Human placenta sphingomyelinase, an exogenous acidic pH-optimum sphingomyelinase, induces oxidative stress, glutathione depletion, and apoptosis in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

A novel inhibitor of ceramide trafficking from the endoplasmic reticulum to the site of sphingomyelin synthesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Induction of apoptotic DNA fragmentation and cell death by natural ceramide

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Metabolic effects of short-chain ceramide and glucosylceramide on sphingolipids and protein kinase C.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Effect of aromatic short-chain analogues of ceramide on axonal growth in hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Synthesis and biological evaluation of ceramide analogues with substituted aromatic rings or an allylic fluoride in the sphingoid moiety.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Synthesis of new trans double-bond sphingolipid analogues: Delta(4,6) and Delta(6) ceramides

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Synthesis and apoptogenic activity of fluorinated ceramide and dihydroceramide analogues.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Design, synthesis, and characterization of the antitumor activity of novel ceramide analogues

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

A novel approach towards studying non-genotoxic enediynes as potential anticancer therapeutics.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Glucosphingolipids as sites of action in the chemotherapy of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Chemotherapy by slowing glucosphingolipid synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Regulation of phospholipase C-gamma activity by glycosphingolipids

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Improved inhibitors of glucosylceramide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Glycosphingolipid depletion in fabry disease lymphoblasts with potent inhibitors of glucosylceramide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Treatment of Gaucher disease with an enzyme inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

The relationship between the structure of the headgroup of sphingolipids and their ability to form complex high axial ratio microstructures

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Continuous and highly variable rate controlled release of model drugs from sphingolipid-based complex high axial ratio microstructures.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Stimulation in vitro of galactocerebroside galactosidase by N-decanoyl 2-amino-2-methylpropanol

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Synthetic inhibitors of galactocerebroside biosynthesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Synthetic inhibitors of glucocerebroside β-glucosidase

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Glycosyltransferases of rat brain that make cerebrosides: substrate specificity, inhibitors, and abnormal products

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Short chain ceramides as substrates for glucocerebroside synthetase. Differences between liver and brain enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Analogs of ceramide that inhibit glucocerebroside synthetase in mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Bcl-2 antagonizes apoptotic cell death induced by two new ceramide analogues.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Comparison of the metabolism of L-erythro- and L-threo-sphinganines and ceramides in cultured cells and in subcellular fractions.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Regulation of mitogenesis by kinins in arterial smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Doxorubicin-induced persistent oxidative stress to cardiac myocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Protein kinase Cdelta amplifies ceramide formation via mitochondrial signaling in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Regulation of UDP-glucose:ceramide glucosyltransferase-1 by ceramide

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Inhibition of cell proliferation, invasion, tumor growth and metastasis by an oral non-antimicrobial tetracycline analog (COL-3) in a metastatic prostate cancer model

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

CMT-3, a chemically modified tetracycline, inhibits bony metastases and delays the development of paraplegia in a rat model of prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Sequential operation of ceramide synthesis and ICE cascade in CPT-11-initiated apoptotic death signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Cell cycle-independent induction of apoptosis by the anti-tumor drug Flavopiridol in endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

The cyclin-dependent kinase inhibitor flavopiridol induces apoptosis in human leukemia cells (U937) through the mitochondrial rather than the receptor-mediated pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Growth inhibition and apoptosis of myeloma cells by the CDK inhibitor flavopiridol

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Baicalin is a major component of PC-SPES which inhibits the proliferation of human cancer cells via apoptosis and cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Chemoprevention of colonic aberrant crypt foci by an inducible nitric oxide synthase-selective inhibitor.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Curcumin, a natural plant phenolic food additive, inhibits cell proliferation and induces cell cycle changes in colon adenocarcinoma cell lines by a prostaglandin-independent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Ciprofloxacin induces apoptosis and inhibits proliferation of human colorectal carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

De novo-synthesized ceramide is involved in cannabinoid-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Metabolism of delta 9-tetrahydrocannabinol by cytochrome P450 isozymes purified from hepatic microsomes of monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Induction of apoptosis by arachidonic acid in human retinoblastoma Y79 cells: involvement of oxidative stress.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Synthesis and pharmacology of a hybrid cannabinoid

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

3-(1',1'-Dimethylbutyl)-1-deoxy-delta8-THC and related compounds: synthesis of selective ligands for the CB2 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Involvement of sphingomyelin hydrolysis and the mitogen-activated protein kinase cascade in the Delta9-tetrahydrocannabinol-induced stimulation of glucose metabolism in primary astrocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Increased basal glucose production in type 1 Gaucher's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Differential effects of enzyme supplementation therapy on manifestations of type 1 Gaucher disease

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Clinical use of selective estrogen receptor modulators

1 reference

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7 January 2021

Selective estrogen receptor modulation: the search for an ideal hormonal therapy for breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Lactosylceramide is essential for the osteoclastogenesis mediated by macrophage-colony-stimulating factor and receptor activator of nuclear factor-kappa B ligand.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Tumor necrosis factor-alpha supports the survival of osteoclasts through the activation of Akt and ERK.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

1 alpha,25-dihydroxyvitamin D3 increases TGF beta 1 binding to human osteoblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

NAD(P)H (quinone acceptor) oxidoreductase (DT-diaphorase)-mediated two-electron reduction of anthraquinone-based antitumour agents and generation of hydroxyl radicals

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Daunorubicin- and mitoxantrone-triggered phosphatidylcholine hydrolysis: implication in drug-induced ceramide generation and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Functions of 1alpha,25-dihydroxyvitamin D(3) in mammary gland: from normal development to breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

1Alpha,25-dihydroxyvitamin D3 protects human keratinocytes from apoptosis by the formation of sphingosine-1-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Structure-activity studies of antitumor agent irofulven (hydroxymethylacylfulvene) and analogues

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Enhanced antitumor activity of irofulven in combination with thiotepa or mitomycin C.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Dexamethasone modulates rat renal brush border membrane phosphate transporter mRNA and protein abundance and glycosphingolipid composition

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Rapid kidney changes resulting from glycosphingolipid depletion by treatment with a glucosyltransferase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

A role for glycosphingolipid accumulation in the renal hypertrophy of streptozotocin-induced diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Ipso-substitution by cytochrome P450 with conversion of p-hydroxybenzene derivatives to hydroquinone: evidence for hydroperoxo-iron as the active oxygen species

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Immunochemical visualization and identification of rat liver proteins adducted by 2,6-di-tert-butyl-4-methylphenol (BHT)

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Characterization of a new endogenous vitamin A metabolite

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Activation of neutral sphingomyelinase participates in ethanol-induced apoptosis in Hep G2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Selective hydrolysis of a mitochondrial pool of sphingomyelin induces apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Silencing of pi-class glutathione S-transferase in MDA PCa 2a and MDA PCa 2b cells

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

Preneoplastic prostate lesions: an opportunity for prostate cancer prevention

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2802%2900609-0

7 January 2021

10.1016/S0968-0896(02)00609-0

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12713822