Genetic and Epigenetic Mosaicism in Cancer Precursor Tissues (Q35118470)

6 August 2017

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title

Genetic and epigenetic mosaicism in cancer precursor tissues (English)

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6 August 2017

Genetic and Epigenetic Mosaicism in Cancer Precursor Tissues (English)

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

history and philosophy of science

29 December 2023

main subject

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

29 December 2023

author name string

Benjamin Tycko

1

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6 August 2017

language of work or name

English

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publication date

1 March 2003

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full work available at URL

6 August 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1749-6632.2003.tb05961.x

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

https://nyaspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1749-6632.2003.tb05961.x

29 December 2023

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Annals of the New York Academy of Sciences

29 December 2023

published in

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6 August 2017

983

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6 August 2017

43-54

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hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis

6 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2003.TB05961.X

CpG island methylation in colorectal adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2003.TB05961.X

CpG island methylation in aberrant crypt foci of the colorectum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2003.TB05961.X

Aberrant methylation of preproenkephalin and p16 genes in pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2003.TB05961.X

Allelic loss is often the first hit in the biallelic inactivation of the p53 and DPC4 genes during pancreatic carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2003.TB05961.X

Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2003.TB05961.X

Human Cancer Syndromes: Clues to the Origin and Nature of Cancer

21 January 2018

1

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Measurement of in vivo mutations in human lymphocytes

29 December 2023

2

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Spectrum of somatic mutation at the hypoxanthine phosphoribosyltransferase (hprt) gene of healthy people.

29 December 2023

3

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Interindividual variation in mitotic recombination

29 December 2023

4

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Loss of heterozygosity induced by a chromosomal double-strand break

29 December 2023

6

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Loss of heterozygosity or: how I learned to stop worrying and love mitotic recombination

29 December 2023

7

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Colorectal goblet cell sialomucin heterogeneity: its relation to malignant disease

29 December 2023

8

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Racial variation in the O-acetylation phenotype of human colonic mucosa.

29 December 2023

9

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Unicryptal loss of heterozygosity in hereditary non-polyposis colorectal cancer

29 December 2023

10

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Human colonic stem cell mutation frequency with and without irradiation

29 December 2023

11

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

High frequency in vivo loss of heterozygosity is primarily a consequence of mitotic recombination

29 December 2023

12

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Mitotic recombination produces the majority of recessive fibroblast variants in heterozygous mice.

29 December 2023

13

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Mitotic recombination is suppressed by chromosomal divergence in hybrids of distantly related mouse strains

29 December 2023

14

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Differential effects of base-pair mismatch on intrachromosomal versus extrachromosomal recombination in mouse cells

29 December 2023

15

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Genetic mosaicism in normal tissues of Wilms' tumour patients

29 December 2023

17

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Genomic imprinting and Wilms' tumor

29 December 2023

18

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

"Mistakes happen": somatic mutation and disease

29 December 2023

19

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Loss of heterozygosity in normal tissue adjacent to breast carcinomas.

29 December 2023

20

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Loss of heterozygosity at 3p in benign lesions preceding invasive breast cancer

29 December 2023

21

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Loss of heterozygosity in tumour-adjacent normal tissue of breast and bladder cancer

29 December 2023

22

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Microsatellite analysis of endometriosis reveals loss of heterozygosity at candidate ovarian tumor suppressor gene loci

29 December 2023

24

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Genetic and epigenetic alterations in normal bladder epithelium in patients with metachronous bladder cancer

29 December 2023

25

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Clonal genetic alterations in the lungs of current and former smokers

29 December 2023

26

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints

29 December 2023

27

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Loss of chromosome arms 3p and 9p and inactivation ofP16INK4a in normal epithelium of patients with primary lung cancer

29 December 2023

28

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

The fundamental role of epigenetic events in cancer

29 December 2023

29

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Epigenetic gene silencing in cancer

29 December 2023

30

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Increase in the frequency of p16INK4 gene inactivation by hypermethylation in lung cancer during the process of metastasis and its relation to the status of p53

29 December 2023

34

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Mechanisms of p16INK4A inactivation in non small-cell lung cancers

29 December 2023

35

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Extensive methylation of hMLH1 promoter region predominates in proximal colon cancer with microsatellite instability.

29 December 2023

36

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.

29 December 2023

38

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Not hMSH2 but hMLH1 is frequently silenced by hypermethylation in endometrial cancer but rarely silenced in pancreatic cancer with microsatellite instability

29 December 2023

42

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers

29 December 2023

43

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Aberrant promoter methylation of multiple genes in bronchial brush samples from former cigarette smokers

29 December 2023

45

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis

29 December 2023

46

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis

29 December 2023

47

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Serrated route to colorectal cancer: back street or super highway?

29 December 2023

50

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Aberrant crypt foci in the human colon: frequency and histologic patterns in patients with colorectal cancer or diverticular disease.

29 December 2023

51

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Pancreatic intraepithelial neoplasia and infiltrating adenocarcinoma: analysis of progression and recurrence by DPC4 immunohistochemical labeling

29 December 2023

53

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Imprinting of a genomic domain of 11p15 and loss of imprinting in cancer: an introduction

29 December 2023

56

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Epigenetic lesions at the H19 locus in Wilms' tumour patients

29 December 2023

57

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Epigenetic changes encompassing the IGF2/H19 locus associated with relaxation of IGF2 imprinting and silencing of H19 in Wilms tumor

29 December 2023

58

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Multipoint analysis of human chromosome 11p15/mouse distal chromosome 7: inclusion of H19/IGF2 in the minimal WT2 region, gene specificity of H19 silencing in Wilms' tumorigenesis and methylation hyper-dependence of H19 imprinting

29 December 2023

59

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Genomic imprinting and cancer

29 December 2023

60

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Tumor development in the Beckwith-Wiedemann syndrome is associated with a variety of constitutional molecular 11p15 alterations including imprinting defects of KCNQ1OT1.

29 December 2023

61

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Epigenotype-phenotype correlations in Beckwith-Wiedemann syndrome

29 December 2023

62

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Epigenetic alterations of H19 and LIT1 distinguish patients with Beckwith-Wiedemann syndrome with cancer and birth defects

29 December 2023

63

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

Inactivation of WT1 in nephrogenic rests, genetic precursors to Wilms' tumour

29 December 2023

64

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https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05961.X

29 December 2023

Identifiers

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6 August 2017

1 reference