Hydrolytic nucleoside and nucleotide deamination, and genetic instability: a possible link between RNA-editing enzymes and cancer? (Q35119646)

6 August 2017

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title

Hydrolytic nucleoside and nucleotide deamination, and genetic instability: a possible link between RNA-editing enzymes and cancer? (English)

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6 August 2017

Shrikant Anant

1

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PubMed ID

12727140

6 August 2017

Nicholas O Davidson

series ordinal

2

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PubMed ID

12727140

6 August 2017

language of work or name

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1 April 2003

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Trends in Molecular Medicine

6 August 2017

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6 August 2017

9

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6 August 2017

4

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6 August 2017

147-152

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RNA editing by base deamination: more enzymes, more targets, new mysteries

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Development. Survival is impossible without an editor.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

A-to-I editing: new and old sites, functions and speculations

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Underediting of glutamate receptor GluR-B mRNA in malignant gliomas

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Recent progress in understanding apolipoprotein B.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Functions and mechanisms of RNA editing

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Inosine exists in mRNA at tissue-specific levels and is most abundant in brain mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

RED2, a brain-specific member of the RNA-specific adenosine deaminase family

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Purification and molecular cloning of a novel essential component of the apolipoprotein B mRNA editing enzyme-complex

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Molecular cloning of an apolipoprotein B messenger RNA editing protein

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Molecular mechanisms of apolipoprotein B mRNA editing

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

APOLIPOPROTEIN B: mRNA editing, lipoprotein assembly, and presecretory degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Mutagenesis of apobec-1 complementation factor reveals distinct domains that modulate RNA binding, protein-protein interaction with apobec-1, and complementation of C to U RNA-editing activity

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Intracellular trafficking determinants in APOBEC-1, the catalytic subunit for cytidine to uridine editing of apolipoprotein B mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Inhibition of the apolipoprotein B mRNA editing enzyme-complex by hnRNP C1 protein and 40S hnRNP complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

A 40 kilodalton rat liver nuclear protein binds specifically to apolipoprotein B mRNA around the RNA editing site

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Cloning of an Apobec-1-binding protein that also interacts with apolipoprotein B mRNA and evidence for its involvement in RNA editing

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Apolipoprotein B mRNA editing is associated with UV crosslinking of proteins to the editing site

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Hyperediting of multiple cytidines of apolipoprotein B mRNA by APOBEC-1 requires auxiliary protein(s) but not a mooring sequence motif

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

eIF4G: a multipurpose ribosome adapter?

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

A new translational regulator with homology to eukaryotic translation initiation factor 4G

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Protein synthesis initiation factor 4G.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Essential role of NAT1/p97/DAP5 in embryonic differentiation and the retinoic acid pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Low expression of the apolipoprotein B mRNA-editing transgene in mice reduces LDL levels but does not cause liver dysplasia or tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Regulatable liver expression of the rabbit apolipoprotein B mRNA-editing enzyme catalytic polypeptide 1 (APOBEC-1) in mice lacking endogenous APOBEC-1 leads to aberrant hyperediting

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

NF1 tumor suppressor gene function: narrowing the GAP

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

The neurofibromatosis type I messenger RNA undergoes base-modification RNA editing

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

C-->U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein B mRNA-editing enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Evolutionary origins of apoB mRNA editing: catalysis by a cytidine deaminase that has acquired a novel RNA-binding motif at its active site

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

An AU-rich sequence element (UUUN[A/U]U) downstream of the edited C in apolipoprotein B mRNA is a high-affinity binding site for Apobec-1: binding of Apobec-1 to this motif in the 3' untranslated region of c-myc increases mRNA stability

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Escherichia coli cytidine deaminase provides a molecular model for ApoB RNA editing and a mechanism for RNA substrate recognition

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Secondary structure for the apolipoprotein B mRNA editing site. Au-binding proteins interact with a stem loop

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

AU-rich elements: characterization and importance in mRNA degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: the functional sequence within AU-rich elements may be UUAUUUA(U/A)(U/A).

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

The role of cyclooxygenases in inflammation, cancer, and development

1 reference

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7 January 2021

Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells

1 reference

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7 January 2021

Cyclooxygenase-2: a therapeutic target

1 reference

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7 January 2021

A selective cyclooxygenase 2 inhibitor suppresses the growth of H-ras-transformed rat intestinal epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Prostaglandin levels in human colorectal mucosa: effects of sulindac in patients with familial adenomatous polyposis

1 reference

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7 January 2021

COX-2: a target for colon cancer prevention

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

An alternatively spliced form of apobec-1 messenger RNA is overexpressed in human colon cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Absence of APOBEC-1 mediated mRNA editing in human carcinomas.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Apobec-1 transcription in rat colon cancer: decreased apobec-1 protein production through alterations in polysome distribution and mRNA translation associated with upstream AUGs

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

APOBEC-2, a cardiac- and skeletal muscle-specific member of the cytidine deaminase supergene family

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

ARCD-1, an apobec-1-related cytidine deaminase, exerts a dominant negative effect on C to U RNA editing

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

RNA Editing of the Glutamate Receptor Subunits GluR2 and GluR6 in Human Brain Tissue

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900032-7

7 January 2021

10.1016/S1471-4914(03)00032-7

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12727140