Gene therapy for arthritis (Q35122176)

6 August 2017

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title

Gene therapy for arthritis. (English)

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6 August 2017

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Robbins PD

1

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PubMed ID

12732875

6 August 2017

Evans CH

series ordinal

2

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PubMed ID

12732875

6 August 2017

Chernajovsky Y

series ordinal

3

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6 August 2017

1 May 2003

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6 August 2017

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6 August 2017

10

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6 August 2017

10

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6 August 2017

902-911

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3302040

6 August 2017

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cites work

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A multicenter, double-blind, dose-ranging, randomized, placebo-controlled study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis: radiologic progression and correlation of Genant and Larsen scores

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Gene therapy for rheumatoid arthritis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Antigen-specific T cell-mediated gene therapy in collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Pathogenic lymphoid cells engineered to express TGF beta 1 ameliorate disease in a collagen-induced arthritis model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Efficacy of interleukin-10 gene electrotransfer into skeletal muscle in mice with collagen-induced arthritis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Adenoviral-mediated gene transfer to rabbit synovium in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Amelioration of collagen-induced arthritis by CD95 (Apo-1/Fas)-ligand gene transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Therapy and prevention of arthritis by recombinant adeno-associated virus vector with delivery of interleukin-1 receptor antagonist

21 January 2018

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Adeno-associated virus mediates long-term gene transfer and delivery of chondroprotective IL-4 to murine synovium.

21 January 2018

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In vivo gene delivery to synovium by lentiviral vectors.

21 January 2018

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Direct gene delivery strategies for the treatment of rheumatoid arthritis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Successful gene therapy via intraarticular injection of adenovirus vector containing CTLA4IgG in a murine model of type II collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

IL-4 adenoviral gene therapy reduces inflammation, proinflammatory cytokines, vascularization, and bony destruction in rat adjuvant-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Interleukin-13 gene therapy reduces inflammation, vascularization, and bony destruction in rat adjuvant-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Gene therapy for established murine collagen-induced arthritis by local and systemic adenovirus-mediated delivery of interleukin-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Endogenous regulation of a therapeutic transgene restores homeostasis in arthritic joints

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis: comparison of efficacy in animal models with human clinical data

21 January 2018

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Intraarticular expression of biologically active interleukin 1-receptor-antagonist protein by ex vivo gene transfer

21 January 2018

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Suppression of experimental arthritis by gene transfer of interleukin 1 receptor antagonist cDNA.

21 January 2018

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Prevention of murine collagen-induced arthritis in the knee and ipsilateral paw by local expression of human interleukin-1 receptor antagonist protein in the knee

21 January 2018

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In vivo transfer of interleukin-1 receptor antagonist gene in osteoarthritic rabbit knee joints: prevention of osteoarthritis progression

21 January 2018

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In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Plasmid DNA encoding transforming growth factor-beta1 suppresses chronic disease in a streptococcal cell wall-induced arthritis model

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

NF-kappa B as a target for anti-inflammatory gene therapy: suppression of inflammatory responses in monocytic and stromal cells by stable gene transfer of I kappa B alpha cDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Inhibitor of nuclear factor kappaB kinase beta is a key regulator of synovial inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Suppressed severity of collagen-induced arthritis by in vivo transfection of nuclear factor kappaB decoy oligodeoxynucleotides as a gene therapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Suppression of arthritic bone destruction by adenovirus-mediated csk gene transfer to synoviocytes and osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Molecular lysis of synovial lining cells by in vivo herpes simplex virus-thymidine kinase gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Feasibility of adenovirus-mediated nonsurgical synovectomy in collagen-induced arthritis-affected rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Induction of apoptosis in the rheumatoid synovium by Fas ligand gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Gene transfer of p53 to arthritic joints stimulates synovial apoptosis and inhibits inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Induction of the p16INK4a senescence gene as a new therapeutic strategy for the treatment of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Adenoviral transfer of cyclin-dependent kinase inhibitor genes suppresses collagen-induced arthritis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Endostatin gene transfer inhibits joint angiogenesis and pannus formation in inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Angiostatin gene transfer as an effective treatment strategy in murine collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

A two-component expression system that responds to inflammatory stimuli in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

C3-Tat/HIV-regulated intraarticular human interleukin-1 receptor antagonist gene therapy results in efficient inhibition of collagen-induced arthritis superior to cytomegalovirus-regulated expression of the same transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

A novel doxycycline inducible autoregulatory plasmid which displays "on"/"off" regulation suited to gene therapy applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Soluble complement receptor 1 (CD35) delivered by retrovirally infected syngeneic cells or by naked DNA injection prevents the progression of collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Gene therapy of rheumatoid arthritis via cytokine regulation: future perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Prevention of collagen-induced arthritis by gene delivery of soluble p75 tumour necrosis factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Engineering mouse T lymphocytes specific to type II collagen by transduction with a chimeric receptor consisting of a single chain Fv and TCR zeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Syngeneic fibroblasts transfected with a plasmid encoding interleukin-4 as non-viral vectors for anti-inflammatory gene therapy in collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Collagen II-pulsed antigen-presenting cells genetically modified to secrete IL-4 down-regulate collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Modulation of proinflammatory cytokine production in tumour necrosis factor-alpha (TNF-alpha)-transgenic mice by treatment with cells engineered to secrete IL-4, IL-10 or IL-13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Encapsulation in hollow fibres of xenogeneic cells engineered to secrete IL-4 or IL-13 ameliorates murine collagen-induced arthritis (CIA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Amelioration of collagen-induced arthritis and suppression of interferon-gamma, interleukin-12, and tumor necrosis factor alpha production by interferon-beta gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Expression of an efficient small molecular weight tumour necrosis factor/lymphotoxin antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Systemic gene therapy for arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Cutting edge: a murine, IL-12-independent pathway of IFN-gamma induction by gram-negative bacteria based on STAT4 activation by Type I IFN and IL-18 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Signaling crosstalk between RANKL and interferons in osteoclast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Amelioration of established collagen induced arthritis by systemic IL-10 gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Transcription factor decoy for NFkappaB inhibits cytokine and adhesion molecule expressions in synovial cells derived from rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Treatment of murine collagen-induced arthritis by ex vivo extracellular superoxide dismutase gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Amelioration of antigen-induced arthritis in rats by transfer of extracellular superoxide dismutase and catalase genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Paradoxical effects of tissue inhibitor of metalloproteinases 1 gene transfer in collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Anti-cytokine therapy for rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Gene transfer of cytokine inhibitors into human synovial fibroblasts in the SCID mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Rheumatoid arthritis and p53: how oxidative stress might alter the course of inflammatory diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Advances in understanding the genetic basis of rheumatoid arthritis and osteoarthritis: implications for therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

p53 in rheumatoid arthritis: friend or foe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Gene therapy for rheumatoid arthritis. Theoretical considerations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Stem cells for repair of cartilage and bone: the next challenge in osteoarthritis and rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Adenovirus-mediated gene transfer of CTLA-4Ig fusion protein in the suppression of experimental autoimmune arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

7 January 2021

Effective treatment of established murine collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express IL-4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

7 January 2021

Effective treatment of established mouse collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express FasL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

7 January 2021

Adenoviral mediated delivery of FAS ligand to arthritic joints causes extensive apoptosis in the synovial lining

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

7 January 2021

[Antigen-specific T cells transduced with interleukin-10 ameliorate experimentally induced arthritis without impairing the systemic immune response to the antigen]

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

7 January 2021

The type II decoy receptor of IL-1 inhibits murine collagen-induced arthritis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

7 January 2021

Viral IL-10 gene transfer inhibits DTH responses to soluble antigens: evidence for involvement of genetically modified dendritic cells and macrophages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

7 January 2021

The contralateral effect conferred by intra-articular adenovirus-mediated gene transfer of viral IL-10 is specific to the immunizing antigen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

7 January 2021

Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

7 January 2021

Novel therapeutic strategies involving animals, arthritis, and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

7 January 2021

Gene therapy for rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

7 January 2021

Viral IL-10 and soluble TNF receptor act synergistically to inhibit collagen-induced arthritis following adenovirus-mediated gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

7 January 2021

Vasoactive intestinal peptide prevents experimental arthritis by downregulating both autoimmune and inflammatory components of the disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

7 January 2021

IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302040

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302040

1 reference

6 August 2017

1 reference

PubMed ID

12732875