Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma (Q35135650)

24684846

6 August 2017

title

Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma (English)

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6 August 2017

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2

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12 June 2020

R. Kiplin Guy

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12 June 2020

Martine F Roussel

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12 June 2020

Giles W Robinson

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Marie Morfouace

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Marie Morfouace

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David Finkelstein

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12 June 2020

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Clinton F Stewart

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Amar Gajjar

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12 June 2020

author name string

Megan Jacus

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Burgess B Freeman

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David Turner

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12 June 2020

Sarah Robinson

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Frederique Zindy

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Yong-Dong Wang

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Olivier Ayrault

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Laure Bihannic

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Stephanie Puget

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12 June 2020

Xiao-Nan Li

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James M Olson

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12 June 2020

language of work or name

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27 March 2014

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6 August 2017

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12 June 2020

volume

25

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issue

4

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12 June 2020

page(s)

516-529

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Use of molecular biomarkers to quantify the spatial distribution of effects of anticancer drugs in solid tumors

12 June 2020

cites work

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Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.

13 July 2018

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13 July 2018

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Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

13 July 2018

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Phase 2 trial of pemetrexed in children and adolescents with refractory solid tumors: a Children's Oncology Group study

13 July 2018

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Novel mutations target distinct subgroups of medulloblastoma.

13 July 2018

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The clinical implications of medulloblastoma subgroups

13 July 2018

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Global gene expression profiling confirms the molecular fidelity of primary tumor-based orthotopic xenograft mouse models of medulloblastoma

13 July 2018

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Upfront association of carboplatin plus pemetrexed in patients with brain metastases of lung adenocarcinoma.

13 July 2018

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Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

13 July 2018

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A mouse model of the most aggressive subgroup of human medulloblastoma

13 July 2018

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Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations

13 July 2018

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An integrated in vitro and in vivo high-throughput screen identifies treatment leads for ependymoma.

13 July 2018

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The genetic landscape of the childhood cancer medulloblastoma

13 July 2018

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Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables

13 July 2018

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Medulloblastoma comprises four distinct molecular variants

13 July 2018

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Phase I study of decitabine with doxorubicin and cyclophosphamide in children with neuroblastoma and other solid tumors: a Children's Oncology Group study

13 July 2018

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Multiagent chemotherapy studied in a xenograft model of medulloblastoma/primitive neuroectodermal tumour: analysis of the VETOPEC regimen

13 July 2018

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DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.

13 July 2018

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13 July 2018

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H2AX phosphorylation marks gemcitabine-induced stalled replication forks and their collapse upon S-phase checkpoint abrogation

13 July 2018

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Pemetrexed: biochemical and cellular pharmacology, mechanisms, and clinical applications

13 July 2018

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Drug penetration in solid tumours

13 July 2018

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Review of the pemetrexed and gemcitabine combination in patients with advanced-stage non-small cell lung cancer

13 July 2018

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The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation

13 July 2018

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13 July 2018

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Phase I trial and pharmacokinetics of gemcitabine in children with advanced solid tumors

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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A multicenter phase II study of cisplatin, pemetrexed, and bevacizumab in patients with advanced malignant mesothelioma.

27 September 2018

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27 September 2018

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27 September 2018

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Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched.

27 September 2018

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Plasma and cerebrospinal fluid pharmacokinetics of 5-Aza-2'-deoxycytidine in rabbits and dogs

27 September 2018

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12 December 2020

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Cell cycle modulation by a multitargeted antifolate, LY231514, increases the cytotoxicity and antitumor activity of gemcitabine in HT29 colon carcinoma

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10.1016/J.CCR.2014.02.009

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12 June 2020

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24684846

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