Overexpression of PAK1 promotes cell survival in inflammatory bowel diseases and colitis-associated cancer (Q35136001)

6 August 2017

title

Overexpression of PAK1 promotes cell survival in inflammatory bowel diseases and colitis-associated cancer (English)

1 reference

inflammatory bowel diseases

6 August 2017

main subject

0 references

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25569743%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Vineeta Khare

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25569743%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Kyle Dammann

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25569743%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Mario Asboth

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25569743%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Anita Krnjic

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25569743%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Manuela Jambrich

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25569743%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

publication date

1 February 2015

1 reference

Inflammatory Bowel Diseases

6 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25569743%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

21

1 reference

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13 June 2020

issue

2

1 reference

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13 June 2020

page(s)

287-296

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25569743%20AND%20SRC:MED&resulttype=core&format=json

Tracing PAKs from GI inflammation to cancer.

13 June 2020

cites work

1 reference

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28 July 2018

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Antioxidant properties of mesalamine in colitis inhibit phosphoinositide 3-kinase signaling in progenitor cells

28 July 2018

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p-21-Activated kinase 1 mediates gastrin-stimulated proliferation in the colorectal mucosa via multiple signaling pathways

28 July 2018

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28 July 2018

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Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1

28 July 2018

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28 July 2018

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PAK1-dependent MAPK pathway activation is required for colorectal cancer cell proliferation

28 July 2018

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5-Aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer.

28 July 2018

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P-21 activated kinase 1 knockdown inhibits β-catenin signalling and blocks colorectal cancer growth.

28 July 2018

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p21-activated kinase 1: PAK'ed with potential

28 July 2018

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Interaction of mesalasine (5-ASA) with translational initiation factors eIF4 partially explains 5-ASA anti-inflammatory and anti-neoplastic activities

28 July 2018

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Systematic review: molecular chemoprevention of colorectal malignancy by mesalazine.

28 July 2018

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Mesalamine inhibits epithelial beta-catenin activation in chronic ulcerative colitis

28 July 2018

1 reference

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PAK1 interacts with beta-catenin and is required for the regulation of the beta-catenin signalling pathway by gastrins

28 July 2018

1 reference

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p21-activated kinase 1 is activated through the mammalian target of rapamycin/p70 S6 kinase pathway and regulates the replication of hepatitis C virus in human hepatoma cells

28 July 2018

1 reference

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Protein phosphatase 2A is required for mesalazine-dependent inhibition of Wnt/beta-catenin pathway activity

28 July 2018

1 reference

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mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

28 July 2018

1 reference

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A nuclear transport signal in mammalian target of rapamycin is critical for its cytoplasmic signaling to S6 kinase 1.

28 July 2018

1 reference

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Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: a systematic review and metaanalysis of observational studies

28 July 2018

1 reference

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Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma

28 July 2018

1 reference

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

28 July 2018

1 reference

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Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors.

28 July 2018

1 reference

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Pak-1 expression increases with progression of colorectal carcinomas to metastasis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4345971

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

28 July 2018

1 reference

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Stimulation of NFkappa B activity by multiple signaling pathways requires PAK1.

28 July 2018

1 reference

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

28 July 2018

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Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

28 July 2018

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Phosphorylation of β-catenin at serine 663 regulates its transcriptional activity.

28 July 2018

1 reference

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Single nucleotide polymorphisms that increase expression of the guanosine triphosphatase RAC1 are associated with ulcerative colitis

27 September 2018

1 reference

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P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways

27 September 2018

1 reference

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5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint

27 September 2018

1 reference

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The PAK1 autoregulatory domain is required for interaction with NIK in Helicobacter pylori-induced NF-kappaB activation

27 September 2018

1 reference

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Hypoxic macrophages impair autophagy in epithelial cells through Wnt1: relevance in IBD

27 September 2018

1 reference

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p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease

16 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25569743

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1097/MIB.0000000000000281

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25569743%20AND%20SRC:MED&resulttype=core&format=json

release_sbvfaoufsjbj5awwhq2itcghzm

13 June 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/sbvfaoufsjbj5awwhq2itcghzm

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25569743%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference