PAK1-dependent MAPK pathway activation is required for colorectal cancer cell proliferation (Q39410909)

11 September 2017

title

PAK1-dependent MAPK pathway activation is required for colorectal cancer cell proliferation (English)

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11 September 2017

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Haitao Qing

1

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11 September 2017

Wei Gong

2

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11 September 2017

Yufang Che

3

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11 September 2017

Xinying Wang

4

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11 September 2017

Liang Peng

5

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11 September 2017

Yan Liang

6

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11 September 2017

Weifei Wang

7

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11 September 2017

Qiliang Deng

8

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11 September 2017

Hongquan Zhang

9

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11 September 2017

Bo Jiang

10

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11 September 2017

publication date

18 January 2012

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11 September 2017

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11 September 2017

volume

33

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11 September 2017

issue

4

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11 September 2017

page(s)

985-994

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Randomized phase III study of 5-fluorouracil plus high dose folinic acid versus 5-fluorouracil plus folinic acid plus methyl-lomustine for patients with advanced colorectal cancer

11 September 2017

cites work

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Regulation of microfilament reorganization and invasiveness of breast cancer cells by kinase dead p21-activated kinase-1

21 January 2018

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Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1

21 January 2018

1 reference

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p21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

P21-activated kinase is required for mitotic progression and regulates Plk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

p21-activated Kinase-1 Signaling Mediates Cyclin D1 Expression in Mammary Epithelial and Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

PAK1 hyperactivation is sufficient for mammary gland tumor formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Phosphorylated Pak1 level in the cytoplasm correlates with shorter survival time in patients with glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Combined array comparative genomic hybridization and tissue microarray analysis suggest PAK1 at 11q13.5-q14 as a critical oncogene target in ovarian carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

P21-activated kinase 5 is overexpressed during colorectal cancer progression and regulates colorectal carcinoma cell adhesion and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Regulation of PTEN by Rho small GTPases

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

The MAPK signalling pathways and colorectal cancer

21 January 2018

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Targeting JNK for therapeutic benefit: from junk to gold?

21 January 2018

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Physical interaction of the retinoblastoma protein with human D cyclins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Differential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Hypo-phosphorylation of the retinoblastoma protein (pRb) by cyclin D:Cdk4/6 complexes results in active pRb

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Extracellular signal-regulated protein kinase/Jun kinase cross-talk underlies vascular endothelial cell growth factor-induced endothelial cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

CDK4 regulation by TNFR1 and JNK is required for NF-kappaB-mediated epidermal growth control

21 January 2018

1 reference

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AP-1 in cell proliferation and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Signal transduction by the JNK group of MAP kinases

21 January 2018

1 reference

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Inhibition of c-Jun-N-terminal-kinase sensitizes tumor cells to CD95-induced apoptosis and induces G2/M cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

c-Jun N-terminal kinase is essential for growth of human T98G glioblastoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

PAK interacts with NCK and MLK2 to regulate the activation of jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Tumor necrosis factor-alpha induced expression of matrix metalloproteinase-9 through p21-activated kinase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Pak protein kinases and their role in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Caspase activation and disruption of mitochondrial membrane potential during UV radiation-induced apoptosis of human keratinocytes requires activation of protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

p21-activated Kinase 1 (Pak1)-dependent phosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylation of BAD, and Bcl-2 association

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

5-Fluorouracil: mechanisms of action and clinical strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Differential growth inhibition by 5-fluorouracil in human colorectal carcinoma cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and p53 status

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-012-0327-1

Gene expression profiling-based prediction of response of colon carcinoma cells to 5-fluorouracil and camptothecin.

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22252525

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fluorouracil and folinic acid in colon cancer. IMPACT Investigators

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22252525

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Modulation of p21-activated kinase 1 alters the behavior of renal cell carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22252525

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S13277-012-0327-1

1 reference

11 September 2017

1 reference