INGN-225: a dendritic cell-based p53 vaccine (Ad.p53-DC) in small cell lung cancer: observed association between immune response and enhanced chemotherapy effect (Q35136043)

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English	INGN-225: a dendritic cell-based p53 vaccine (Ad.p53-DC) in small cell lung cancer: observed association between immune response and enhanced chemotherapy effect	scientific article

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scholarly article

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Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

INGN-225: a dendritic cell-based p53 vaccine (Ad.p53-DC) in small cell lung cancer: observed association between immune response and enhanced chemotherapy effect (English)

1 reference

Europe PubMed Central

6 August 2017

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based on heuristic

inferred from title

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based on heuristic

inferred from title

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based on heuristic

inferred from title

William Janssen

3

object named as

William E Janssen

1 reference

Europe PubMed Central

6 August 2017

author name string

Alberto A Chiappori

1

1 reference

Europe PubMed Central

6 August 2017

Hatem Soliman

2

1 reference

Europe PubMed Central

6 August 2017

Scott J Antonia

4

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Europe PubMed Central

6 August 2017

Dmitry I Gabrilovich

5

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Europe PubMed Central

6 August 2017

language of work or name

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publication date

1 June 2010

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Europe PubMed Central

6 August 2017

Expert Opinion on Biological Therapy

1 reference

Europe PubMed Central

6 August 2017

10

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Europe PubMed Central

6 August 2017

6

1 reference

Europe PubMed Central

6 August 2017

983-991

1 reference

Europe PubMed Central

6 August 2017

A common gain of function of p53 cancer mutants in inducing genetic instability

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Activated CD4+ T cells dramatically enhance chemotherapeutic tumor responses in vitro and in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Combined modality immunotherapy and chemotherapy: a new perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Paradigm shifts in cancer vaccine therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Cancer statistics, 2008

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Combining Vaccines with Conventional Therapies for Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Tremelimumab (CP-675,206), a cytotoxic T lymphocyte associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancer

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13 July 2018

Cancer vaccines: moving beyond current paradigms

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Enhancing efficacy of therapeutic vaccinations by combination with other modalities

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13 July 2018

Clinical activity and immune modulation in cancer patients treated with CP-870,893, a novel CD40 agonist monoclonal antibody.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

All-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

A randomized phase II study of concurrent docetaxel plus vaccine versus vaccine alone in metastatic androgen-independent prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Unexpected association between induction of immunity to the universal tumor antigen CYP1B1 and response to next therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Topotecan in the treatment of recurrent small cell lung cancer: an update

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Mechanisms and functional significance of tumour-induced dendritic-cell defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Treatment of recurrent small cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Full-length dominant-negative survivin for cancer immunotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

All-trans-retinoic acid eliminates immature myeloid cells from tumor-bearing mice and improves the effect of vaccination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Small cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Immature myeloid cells and cancer-associated immune suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Management of small cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Gain-of-function mutations in the tumor suppressor gene p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Management of small cell lung cancer: current state of the art.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Generation of anti-p53 cytotoxic T lymphocytes from human peripheral blood using autologous dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

The sequence alteration associated with a mutational hotspot in p53 protects cells from lysis by cytotoxic T lymphocytes specific for a flanking peptide epitope

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

A phase II study of paclitaxel in heavily pretreated patients with small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Dendritic cells retrovirally transduced with a model antigen gene are therapeutically effective against established pulmonary metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Dendritic cells transduced with an adenoviral vector encoding a model tumor-associated antigen for tumor vaccination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Tumor eradication by wild-type p53-specific cytotoxic T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Antitumor activity of a monoclonal antibody directed against gastrin-releasing peptide in patients with small cell lung cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Virus-mediated delivery of antigenic epitopes into dendritic cells as a means to induce CTL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Interferon maintenance therapy for small cell lung cancer: improvement in long-term survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Gene therapy for cancer: what have we done and where are we going?

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Interferon alpha-2a and combined chemotherapy as first line treatment in SCLC patients: a randomized trial

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Therapy of murine tumors with p53 wild-type and mutant sequence peptide-based vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Use of recombinant adenovirus for metabolic engineering of mammalian cells.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Minimal epitopes expressed in a recombinant polyepitope protein are processed and presented to CD8+ cytotoxic T cells: implications for vaccine design

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-[3-benzo(b)thienyl]-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

High frequency of somatically acquired p53 mutations in small-cell lung cancer cell lines and tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

13 July 2018

Clinical responsiveness of glioblastoma multiforme to chemotherapy after vaccination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

27 September 2018

An effective immunization and cancer treatment with activated dendritic cells transduced with full-length wild-type p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

27 September 2018

Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

27 September 2018

A wild-type sequence p53 peptide presented by HLA-A24 induces cytotoxic T lymphocytes that recognize squamous cell carcinomas of the head and neck.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146364

27 September 2018

Adjunctive interferon-alpha-2c in stage IIIB/IV small-cell lung cancer: a phase III trial

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27 September 2018

Interleukin-2 activity in patients with extensive small-cell lung cancer: a phase II trial of Cancer and Leukemia Group B.

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27 September 2018

Dendritic cells transduced with wild-type p53 gene elicit potent anti-tumour immune responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20420527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor efficacy of wild-type p53-specific CD4(+) T-helper cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20420527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20420527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic cells transduced with full-length wild-type p53 generate antitumor cytotoxic T lymphocytes from peripheral blood of cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20420527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High efficiency adenovirus-mediated gene transfer to human dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20420527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunization with wild-type p53 gene sequences coadministered with Flt3 ligand induces an antigen-specific type 1 T-cell response

1 reference

https://pubmed.ncbi.nlm.nih.gov/20420527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination of p53 cancer vaccine with chemotherapy in patients with extensive stage small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20420527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of mutant p53 proteins in lung cancer correlates with the class of p53 gene mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20420527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1517/14712598.2010.484801

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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