The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease (Q35155012)

6 August 2017

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease (English)

1 reference

6 August 2017

0 references

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Monica Bodogai

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Dongin Kim

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

Thirumala-Devi Kanneganti

3 June 2020

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Peter A Crawford

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

author name string

Yun-Hee Youm

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Kim Y Nguyen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Emily L Goldberg

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Dominic D'Agostino

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Noah Planavsky

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Christopher Lupfer

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Seokwon Kang

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Tamas L Horvath

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Tarek M Fahmy

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Arya Biragyn

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Emad Alnemri

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Vishwa Deep Dixit

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

language of work or name

English

0 references

publication date

16 February 2015

1 reference

6 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

page(s)

263-269

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

3 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4352123/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nm.3804

0 references

cites work

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352123

Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes

13 July 2018

1 reference

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Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis

13 July 2018

1 reference

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Ketone bodies as signaling metabolites.

13 July 2018

1 reference

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Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging

13 July 2018

1 reference

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Mechanisms of NOD-like receptor-associated inflammasome activation

13 July 2018

1 reference

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K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter

13 July 2018

1 reference

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13 July 2018

1 reference

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Activation and regulation of the inflammasomes

13 July 2018

1 reference

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Impact of peripheral ketolytic deficiency on hepatic ketogenesis and gluconeogenesis during the transition to birth.

13 July 2018

1 reference

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Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile

13 July 2018

1 reference

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Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352123

Ketone body metabolism and cardiovascular disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352123

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

13 July 2018

1 reference

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The ketogenic diet: metabolic influences on brain excitability and epilepsy

13 July 2018

1 reference

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Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352123

Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling

13 July 2018

1 reference

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Pathogen-associated molecular patterns on biomaterials: a paradigm for engineering new vaccines

13 July 2018

1 reference

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The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352123

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

13 July 2018

1 reference

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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

13 July 2018

1 reference

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Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis

13 July 2018

1 reference

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Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity.

13 July 2018

1 reference

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The inflammasomes: guardians of the body

13 July 2018

1 reference

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The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352123

Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352123

Gout-associated uric acid crystals activate the NALP3 inflammasome

13 July 2018

1 reference

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Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.

13 July 2018

1 reference

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(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.

13 July 2018

1 reference

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Blunted febrile response to intravenous endotoxin in starved rats

13 July 2018

1 reference

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Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352123

Noncanonical inflammasome activation by intracellular LPS independent of TLR4.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352123

The ketone body β-hydroxybutyric acid influences agouti-related peptide expression via AMP-activated protein kinase in hypothalamic GT1-7 cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352123

Ketone bodies stimulate chaperone-mediated autophagy

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352123

NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.3804

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NM.3804

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

3 June 2020

1050004883

0 references

Fatcat ID

release_tdzduma6mjfeplu3jte66wffky

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tdzduma6mjfeplu3jte66wffky

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25686106%20AND%20SRC:MED&resulttype=core&format=json