Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes (Q24339219)

25 June 2017

Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes (English)

1 reference

25 June 2017

1 reference

PYD and CARD domain containing

1 reference

Caspase 1

1 reference

NLR family pyrin domain containing 3

1 reference

identical protein binding

1 reference

1 reference

Gunnar F Schröder

7

0 references

Edward H Egelman

object named as

Edward H Egelman

10

0 references

Alvin Lu

object named as

Alvin Lu

1

0 references

author name string

Venkat Giri Magupalli

2

1 reference

25 June 2017

Jianbin Ruan

3

1 reference

25 June 2017

Qian Yin

4

1 reference

25 June 2017

Maninjay K Atianand

5

1 reference

25 June 2017

Matthijn R Vos

6

1 reference

25 June 2017

Katherine A Fitzgerald

8

1 reference

25 June 2017

Hao Wu

9

1 reference

25 June 2017

language of work or name

English

0 references

publication date

1 March 2014

1 reference

25 June 2017

1 reference

25 June 2017

156

1 reference

25 June 2017

1193-1206

1 reference

25 June 2017

6

1 reference

Mutations in NALP12 cause hereditary periodic fever syndromes

25 June 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Regulation of inflammasome signaling

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Helical assembly in the death domain (DD) superfamily

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Structural architecture of the CARMA1/Bcl10/MALT1 signalosome: nucleation-induced filamentous assembly

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Crystal structure of NLRC4 reveals its autoinhibition mechanism

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Structure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Crystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome Assembly

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Structure and Interdomain Dynamics of Apoptosis-associated Speck-like Protein Containing a CARD (ASC)

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Crystal Structure of Procaspase-1 Zymogen Domain Reveals Insight into Inflammatory Caspase Autoactivation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Innate immune recognition: mechanisms and pathways

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

7 April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Inflammasomes in health and disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Higher-order assemblies in a new paradigm of signal transduction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Apoptosome structure, assembly, and procaspase activation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Inflammasomes and their roles in health and disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Sensing and reacting to microbes through the inflammasomes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Direct electron detection yields cryo-EM reconstructions at resolutions beyond 3/4 Nyquist frequency

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Atomic resolution cryo electron microscopy of macromolecular complexes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Combining efficient conformational sampling with a deformable elastic network model facilitates structure refinement at low resolution

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Infevers: an evolving mutation database for auto-inflammatory syndromes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

A robust algorithm for the reconstruction of helical filaments using single-particle methods

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Site-specific N-terminal labeling of proteins using sortase-mediated reactions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Leginon: a system for fully automated acquisition of 1000 electron micrographs a day.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000066

Pyrin N-terminal homology domain- and caspase recruitment domain-dependent oligomerization of ASC

30 May 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24630722

12 December 2020

inferred from PubMed ID database lookup

F-actin is a helix with a random variable twist

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24630722

12 December 2020

inferred from PubMed ID database lookup

Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24630722

12 December 2020

inferred from PubMed ID database lookup

Improved side-chain torsion potentials for the Amber ff99SB protein force field

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

1H, 13C and 15N resonance assignments of the pyrin domain from human PYNOD

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

A versatile plasmid expression vector for the production of biotinylated proteins by site-specific, enzymatic modification in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

Determining the 3D structure of human ASC2 protein involved in apoptosis and inflammation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

Death Domain Assembly Mechanism Revealed by Crystal Structure of the Oligomeric PIDDosome Core Complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

The NLRP12 Pyrin Domain: Structure, Dynamics, and Functional Insights

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

Filaments from Ignicoccus hospitalis show diversity of packing in proteins containing N-terminal type IV pilin helices

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

EMAN2: an extensible image processing suite for electron microscopy

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

Ab initio resolution measurement for single particle structures

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

Reconstruction of helical filaments and tubes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

Accurate determination of local defocus and specimen tilt in electron microscopy

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

Structural and Functional Analysis of the NLRP4 Pyrin Domain

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

Version 1.2 of the Crystallography and NMR system

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

Cross-validation in cryo-EM-based structural modeling

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

Three-dimensional Structure of the NLRP7 Pyrin Domain: INSIGHT INTO PYRIN-PYRIN-MEDIATED EFFECTOR DOMAIN SIGNALING IN INNATE IMMUNITY

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

Structure and dynamics of ASC2, a pyrin domain-only protein that regulates inflammatory signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

Coot: model-building tools for molecular graphics

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

PHENIX: a comprehensive Python-based system for macromolecular structure solution

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2014.02.008

7 January 2021

10.1016/J.CELL.2014.02.008

Identifiers

DOI

1 reference

OpenCitations bibliographic resource ID

25 June 2017

331782

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference