Genetically determined phenotype covariation networks control bone strength (Q35157836)

6 August 2017

title

Genetically determined phenotype covariation networks control bone strength (English)

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6 August 2017

1 reference

Hayden-William Courtland

series ordinal

2

object named as

Hayden-William Courtland

1 reference

6 August 2017

Karl J Jepsen

1

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6 August 2017

Joseph H Nadeau

series ordinal

3

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6 August 2017

publication date

1 July 2010

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Journal of Bone and Mineral Research

6 August 2017

published in

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6 August 2017

volume

25

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6 August 2017

issue

7

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6 August 2017

page(s)

1581-1593

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Interindividual variation in functionally adapted trait sets is established during postnatal growth and predictable based on bone robustness

6 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

A delay in pubertal onset affects the covariation of body weight, estradiol, and bone size

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Choice of study phenotype in osteoporosis genetic research

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Genetic factors for resistance to diet-induced obesity and associated metabolic traits on mouse chromosome 17.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Phenotypic integration of skeletal traits during growth buffers genetic variants affecting the slenderness of femora in inbred mouse strains

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Phenotypic integration among trabecular and cortical bone traits establishes mechanical functionality of inbred mouse vertebrae

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Fourier transform infrared imaging microspectroscopy and tissue-level mechanical testing reveal intraspecies variation in mouse bone mineral and matrix composition.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Prediction of incident hip fracture risk by femur geometry variables measured by hip structural analysis in the study of osteoporotic fractures

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Complex genetic regulation of bone mineral density and insulin-like growth factor-I in C57BL/6J-Chr #A/J/NaJ chromosome substitution strains

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

A close examination of genes within quantitative trait loci of bone mineral density in whole mouse genome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Identification of quantitative trait loci affecting murine long bone length in a two-generation intercross of LG/J and SM/J Mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Biological co-adaptation of morphological and composition traits contributes to mechanical functionality and skeletal fragility

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Bivariate linkage study of proximal hip geometry and body size indices: the Framingham study

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Genetic randomization reveals functional relationships among morphologic and tissue-quality traits that contribute to bone strength and fragility

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Construction of the femoral neck during growth determines its strength in old age.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Quantitative trait loci for BMD and bone strength in an intercross between domestic and wildtype chickens

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Molecular genetic studies of gene identification for osteoporosis: a 2004 update

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Variability, compensation and homeostasis in neuron and network function

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Who's afraid of the big bad Wolff?: "Wolff's law" and bone functional adaptation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Low width of tubular bones is associated with increased risk of fragility fracture in elderly men--the MINOS study.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Epistatic pleiotropy and the genetic architecture of covariation within early and late-developing skull trait complexes in mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Quantitative trait loci analysis of structural and material skeletal phenotypes in C57BL/6J and DBA/2 second-generation and recombinant inbred mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Integration and modularity of quantitative trait locus effects on geometric shape in the mouse mandible

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Mapping quantitative trait loci that influence serum insulin-like growth factor binding protein-5 levels in F2 mice (MRL/MpJ X SJL/J).

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Mapping quantitative trait loci that influence femoral cross-sectional area in mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Epidemiology and outcomes of osteoporotic fractures

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Map Manager QTX, cross-platform software for genetic mapping

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Bone strength and related traits in HcB/Dem recombinant congenic mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

From genotype to phenotype: buffering mechanisms and the storage of genetic information

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Analysing complex genetic traits with chromosome substitution strains

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Hsp90 as a capacitor for morphological evolution

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Confidence intervals in QTL mapping by bootstrapping

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Empirical threshold values for quantitative trait mapping

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Bone "mass" and the "mechanostat": a proposal.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

POSTMENOPAUSAL OSTEOPOROSIS

13 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FJBMR.41

Developmental Integration and the Evolution of Pleiotropy

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FJBMR.41

Short-term exercise in mice increases tibial post-yield mechanical properties while two weeks of latency following exercise increases tissue-level strength.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Cardiac mass and cardiomyocyte size are governed by different genetic loci on either autosomes or chromosome Y in recombinant inbred mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Accretion of bone quantity and quality in the developing mouse skeleton

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Genetic effects on bone mechanotransduction in congenic mice harboring bone size and strength quantitative trait loci

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Genetic dissection of complex traits with chromosome substitution strains of mice.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Brittle IV mouse model for osteogenesis imperfecta IV demonstrates postpubertal adaptations to improve whole bone strength

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Congenic mice reveal sex-specific genetic regulation of femoral structure and strength.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

FEMORAL EXPANSION IN AGING WOMEN: IMPLICATIONS FOR OSTEOPOROSIS AND FRACTURES.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Developmental integration in a complex morphological structure: how distinct are the modules in the mouse mandible?

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Quantitative trait loci for femoral size and shape in a genetically heterogeneous mouse population

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Genetic dissection of femur breaking strength in a large population (MRL/MpJ x SJL/J) of F2 Mice: single QTL effects, epistasis, and pleiotropy

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Activity, climate, and postcranial robusticity: implications for modern human origins and scenarios of adaptive change

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Genetic loci influencing natural variations in femoral bone morphometry in mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Prediction of hip fractures from pelvic radiographs: the study of osteoporotic fractures. The Study of Osteoporotic Fractures Research Group

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154000

Ground reaction forces, bone characteristics, and tibial stress fracture in male runners

27 September 2018

1 reference

12 December 2020

Bone brittleness varies with genetic background in A/J and C57BL/6J inbred mice

1 reference

12 December 2020

Quantitative trait loci for periosteal circumference (PC): identification of single loci and epistatic effects in F2 MRL/SJL mice

1 reference

12 December 2020

Genetic Effects for Femoral Biomechanics, Structure, and Density in C57BL/6J and C3H/HeJ Inbred Mouse Strains

1 reference

12 December 2020

Structural and biomechanical basis of sexual dimorphism in femoral neck fragility has its origins in growth and aging

1 reference

12 December 2020

Chromosome substitution strains: some quantitative considerations for genome scans and fine mapping

1 reference

12 December 2020

Quantitative trait loci that modulate femoral mechanical properties in a genetically heterogeneous mouse population

1 reference

12 December 2020

Varying contributions of growth and ageing to racial and sex differences in femoral neck structure and strength in old age

1 reference

12 December 2020

Whole-genome scan for linkage to bone strength and structure in inbred Fischer 344 and Lewis rats

1 reference

12 December 2020

Genetic variation in bone growth patterns defines adult mouse bone fragility

1 reference

12 December 2020

A simple regression method for mapping quantitative trait loci in line crosses using flanking markers

1 reference

12 December 2020

The influence of collagen fiber orientation and other histocompositional characteristics on the mechanical properties of equine cortical bone

1 reference

12 December 2020

Femur mechanical properties in the F2 progeny of an NZB/B1NJ x RF/J cross are regulated predominantly by genetic loci that regulate bone geometry

1 reference

12 December 2020

The contribution of epistatic pleiotropy to the genetic architecture of covariation among polygenic traits in mice

1 reference

12 December 2020

Genetics of osteoporosis

1 reference

12 December 2020

Fine mapping dissects pleiotropic growth quantitative trait locus into linked loci

1 reference

12 December 2020

Quantitative trait loci that determine mouse tibial nanoindentation properties in an F2 population derived from C57BL/6J x C3H/HeJ

1 reference

12 December 2020

Recombinant inbred strain panels: a tool for systems genetics

1 reference

12 December 2020

The area moment of inertia of the tibia: a risk factor for stress fractures

1 reference

12 December 2020

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1 reference

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Cortical thickness and diaphysial diameter of the metacarpal bones from the age of three months to eleven years

1 reference

12 December 2020

Effects of differences in mineralization on the mechanical properties of bone

1 reference

12 December 2020

Bone mineral content in children with fractures

1 reference

12 December 2020

Type I and type II error rates for quantitative trait loci (QTL) mapping studies using recombinant inbred mouse strains

1 reference

12 December 2020

An edited linkage map for the AXB and BXA recombinant inbred mouse strains

1 reference

12 December 2020

Identifiers

DOI

10.1002/JBMR.41

1 reference

6 August 2017

1 reference

6 August 2017

1 reference