The glutamatergic system and Alzheimer's disease: therapeutic implications (Q35163534)

6 August 2017

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title

The glutamatergic system and Alzheimer's disease: therapeutic implications (English)

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6 August 2017

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1

D Allan Butterfield

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6 August 2017

Chava B Pocernich

2

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PubMed ID

12828500

6 August 2017

language of work or name

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1 January 2003

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6 August 2017

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6 August 2017

17

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6 August 2017

641-652

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6 August 2017

9

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https://scigraph.springernature.com/pub.10.2165/00023210-200317090-00004

6 August 2017

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

WISDOM. Will Australian women participate?

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Memantine in moderate-to-severe Alzheimer's disease

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12 December 2020

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12 December 2020

Methionine residue 35 is important in amyloid beta-peptide-associated free radical oxidative stress.

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12 December 2020

D-cycloserine, a positive modulator of the N-methyl-D-aspartate receptor, enhances performance of learning tasks in rats.

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12 December 2020

Effect on memory processing by D-cycloserine, an agonist of the NMDA/glycine receptor

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12 December 2020

Protective effects of ifenprodil against glutamate-induced neurotoxicity in cultured retinal neurons.

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12 December 2020

Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1-40) in cultured hippocampal neurons

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12 December 2020

No interaction of memantine with acetylcholinesterase inhibitors approved for clinical use.

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12 December 2020

Enhancement of beta-amyloid peptide A beta(1-40)-mediated neurotoxicity by glutamine synthetase.

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12 December 2020

Estrogen enhances uptake of amyloid beta-protein by microglia derived from the human cortex

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12 December 2020

Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations

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12 December 2020

Neuron loss in APP transgenic mice

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12 December 2020

Advances in Alzheimer's disease

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12 December 2020

Elevation of brain glutathione by gamma-glutamylcysteine ethyl ester protects against peroxynitrite-induced oxidative stress

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12 December 2020

Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo

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12 December 2020

17Beta-estradiol attenuates oxidative impairment of synaptic Na+/K+-ATPase activity, glucose transport, and glutamate transport induced by amyloid beta-peptide and iron

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12 December 2020

Resource utilisation and cost analysis of memantine in patients with moderate to severe Alzheimer's disease

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12 December 2020

Milacemide and Other Drugs Active at Glutamate NMDA Receptors as Potential Treatment for Dementia

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12 December 2020

Abnormal cerebral metabolite concentrations in patients with probable Alzheimer disease

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12 December 2020

Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides

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12 December 2020

Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress.

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12 December 2020

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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12 December 2020

Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid beta-peptide (1-42) in a transgenic Caenorhabditis elegans model.

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12 December 2020

Excitatory amino acids and Alzheimer's disease

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12 December 2020

Glutamate-, glutaminase-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease

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12 December 2020

Amino-alkyl-cyclohexanes as a novel class of uncompetitive NMDA receptor antagonists

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12 December 2020

Postsynaptic signaling and plasticity mechanisms

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12 December 2020

Estrogen for Alzheimer's disease in women: randomized, double-blind, placebo-controlled trial

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12 December 2020

Signal-processing machines at the postsynaptic density

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12 December 2020

Amyloid beta-peptide (1-40)-mediated oxidative stress in cultured hippocampal neurons. Protein carbonyl formation, CK BB expression, and the level of Cu, Zn, and Mn SOD mRNA.

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12 December 2020

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

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12 December 2020

An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P

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12 December 2020

Animal models of Alzheimer's disease: glutamatergic denervation as an alternative approach to cholinergic denervation

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12 December 2020

The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42.

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12 December 2020

Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease

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12 December 2020

Estradiol attenuation of beta-amyloid-induced toxicity: a comparison o.

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12 December 2020

High-dose estradiol improves cognition for women with AD: results of a randomized study

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12 December 2020

Effects of injected Alzheimer beta-amyloid cores in rat brain.

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12 December 2020

Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation.

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12 December 2020

The Women’s Health Initiative Memory Study (WHIMS)

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12 December 2020

10.2165/00023210-200317090-00004

Identifiers

DOI

1 reference

PubMed ID

12828500

Dimensions Publication ID

6 August 2017

0 references

1 reference

PubMed ID

12828500