Coordinated regulation of polycomb group complexes through microRNAs in cancer. (Q35167450)

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10 February 2020

title

Coordinated regulation of polycomb group complexes through microRNAs in cancer (English)

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10 February 2020

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6

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Bushra Ateeq

3

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Saravana M Dhanasekaran

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Irfan Asangani

5

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Nallasivam Palanisamy

19

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Zhaohui Steve Qin

20

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Sooryanarayana Varambally

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23

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Qi Cao

1

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ORCID Public Data File 2021

Arul Chinnaiyan

24

object named as

Arul M Chinnaiyan

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10 February 2020

22

Christopher A Maher

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18

Scott A Tomlins

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Xuhong Cao

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Robert J Lonigro

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9

Xiaojun Jing

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8

J Chad Brenner

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2

Ram-Shankar Mani

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13

Arun Dahiya

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Mithil Pandhi

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10 February 2020

author name string

Jung H Kim

7

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10 February 2020

Rui Wang

11

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Yong Li

12

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Lei Wang

14

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Yi-Mi Wu

17

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Jindan Yu

21

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publication date

1 August 2011

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10 February 2020

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10 February 2020

volume

20

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10 February 2020

issue

2

1 reference

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10 February 2020

page(s)

187-199

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Characterization of KRAS rearrangements in metastatic prostate cancer

10 February 2020

cites work

1 reference

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MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2

28 July 2018

1 reference

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Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA

28 July 2018

1 reference

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Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation

28 July 2018

1 reference

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Targeting microRNAs in cancer: rationale, strategies and challenges

28 July 2018

1 reference

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Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells

28 July 2018

1 reference

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MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion

28 July 2018

1 reference

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ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency

28 July 2018

1 reference

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Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

28 July 2018

1 reference

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MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1alpha/HIF-1beta

28 July 2018

1 reference

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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

28 July 2018

1 reference

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An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB

28 July 2018

1 reference

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Polycomb group proteins: navigators of lineage pathways led astray in cancer

28 July 2018

1 reference

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Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells

28 July 2018

1 reference

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Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells

28 July 2018

1 reference

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The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2.

28 July 2018

1 reference

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Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

28 July 2018

1 reference

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The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

28 July 2018

1 reference

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Repression of E-cadherin by the polycomb group protein EZH2 in cancer

28 July 2018

1 reference

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Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation

28 July 2018

1 reference

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The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

28 July 2018

1 reference

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shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development

28 July 2018

1 reference

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A skin microRNA promotes differentiation by repressing 'stemness'.

28 July 2018

1 reference

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MicroRNA-26a targets the histone methyltransferase Enhancer of Zeste homolog 2 during myogenesis

28 July 2018

1 reference

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CD44+ CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis

28 July 2018

1 reference

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let-7 regulates self renewal and tumorigenicity of breast cancer cells

28 July 2018

1 reference

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A polycomb repression signature in metastatic prostate cancer predicts cancer outcome

28 July 2018

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Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer

28 July 2018

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Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

28 July 2018

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Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs

28 July 2018

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Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

28 July 2018

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Isolation and functional characterization of murine prostate stem cells

28 July 2018

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Integrative molecular concept modeling of prostate cancer progression.

28 July 2018

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Expression of the enhancer of zeste homolog 2 is correlated with poor prognosis in human gastric cancer.

28 July 2018

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28 July 2018

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Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing

28 July 2018

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The Polycomb group protein EZH2 directly controls DNA methylation

28 July 2018

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Silencing of microRNAs in vivo with 'antagomirs'

28 July 2018

1 reference

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Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

28 July 2018

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BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing.

28 July 2018

1 reference

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Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer

28 July 2018

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Clinicopathological significance of EZH2 mRNA expression in patients with hepatocellular carcinoma

28 July 2018

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Down-regulation of human DAB2IP gene expression mediated by polycomb Ezh2 complex and histone deacetylase in prostate cancer

28 July 2018

1 reference

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RAS is regulated by the let-7 microRNA family

28 July 2018

1 reference

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Role of histone H2A ubiquitination in Polycomb silencing

28 July 2018

1 reference

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Stem cells and cancer; the polycomb connection

28 July 2018

1 reference

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EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

28 July 2018

1 reference

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EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

28 July 2018

1 reference

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In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

28 July 2018

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MethPrimer: designing primers for methylation PCRs

28 July 2018

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The polycomb group protein EZH2 is involved in progression of prostate cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157014

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

28 July 2018

1 reference

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The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

28 July 2018

1 reference

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The Polycomb complex PRC2 and its mark in life

28 July 2018

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Polycomb group proteins set the stage for early lineage commitment

27 September 2018

1 reference

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The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer

27 September 2018

1 reference

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PKCalpha mediated induction of miR-101 in human hepatoma HepG2 cells

27 September 2018

1 reference

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Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation

27 September 2018

1 reference

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

27 September 2018

1 reference

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Bmi1 regulates stem cells and proliferation and differentiation of committed cells in mammary epithelium.

27 September 2018

1 reference

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Linking miRNA regulation to BCR-ABL expression: the next dimension

27 September 2018

1 reference

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Role of histone H3 lysine 27 methylation in Polycomb-group silencing

27 September 2018

1 reference

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Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression

27 September 2018

1 reference

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Variability in the expression of polycomb proteins in different normal and tumoral tissues. A pilot study using tissue microarrays

16 November 2018

1 reference

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10.1016/J.CCR.2011.06.016

16 November 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21840484%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21840484%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference