The microtubule stabilizer patupilone (epothilone B) is a potent radiosensitizer in medulloblastoma cells (Q35170345)

6 August 2017

title

The microtubule stabilizer patupilone (epothilone B) is a potent radiosensitizer in medulloblastoma cells (English)

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6 August 2017

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ChEBI release 2020-05-28

6

Stefan Rutkowski

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6 August 2017

Christoph Oehler

1

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6 August 2017

André O von Bueren

2

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6 August 2017

Polina Furmanova

3

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6 August 2017

Angela Broggini-Tenzer

4

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6 August 2017

Katrin Orlowski

5

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6 August 2017

Karl Frei

7

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6 August 2017

Michael A Grotzer

8

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6 August 2017

Martin Pruschy

9

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6 August 2017

publication date

9 July 2011

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6 August 2017

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6 August 2017

volume

13

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6 August 2017

issue

9

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6 August 2017

page(s)

1000-1010

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Defective autophagy associated with LC3 puncta in epothilone-resistant cancer cells

6 August 2017

cites work

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Role of the microenvironment for radiosensitization by patupilone

13 July 2018

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RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells

13 July 2018

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Mechanism of G1-like arrest by low concentrations of paclitaxel: next cell cycle p53-dependent arrest with sub G1 DNA content mediated by prolonged mitosis

13 July 2018

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The 2007 WHO classification of tumours of the central nervous system

13 July 2018

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Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells

13 July 2018

1 reference

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In vivo evaluation of ixabepilone (BMS247550), a novel epothilone B derivative, against pediatric cancer models

13 July 2018

1 reference

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Patupilone acts as radiosensitizing agent in multidrug-resistant cancer cells in vitro and in vivo.

13 July 2018

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Role of cell cycle in mediating sensitivity to radiotherapy

13 July 2018

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Vascular targeting agents as cancer therapeutics

13 July 2018

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Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

13 July 2018

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EPO906 (epothilone B): a promising novel microtubule stabilizer

13 July 2018

1 reference

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Adult medulloblastoma: multiagent chemotherapy

13 July 2018

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Epothilones and related structures--a new class of microtubule inhibitors with potent in vivo antitumor activity

13 July 2018

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Metastasis stage, adjuvant treatment, and residual tumor are prognostic factors for medulloblastoma in children: conclusions from the Children's Cancer Group 921 randomized phase III study.

13 July 2018

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Modern treatment strategies in medulloblastoma

13 July 2018

1 reference

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Neuropsychological sequelae of the treatment of children with medulloblastoma

13 July 2018

1 reference

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Cyclic x-ray responses in mammalian cells in vitro

13 July 2018

1 reference

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Improved survival with the use of adjuvant chemotherapy in the treatment of medulloblastoma

13 July 2018

1 reference

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Whole-brain irradiation and decline in intelligence: the influence of dose and age on IQ score

13 July 2018

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Three- and four-year cognitive outcome in children with noncortical brain tumors treated with whole-brain radiotherapy

13 July 2018

1 reference

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Infrequent p53 gene mutations in medulloblastomas.

13 July 2018

1 reference

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Dose reductions of vincristine in children with medulloblastoma treated in the maintenance arm of the prospective multicenter trial HIT'91.

28 July 2018

1 reference

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Phase I trial using patupilone (epothilone B) and concurrent radiotherapy for central nervous system malignancies

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158010

Safety and efficacy of patupilone in patients with advanced ovarian, primary fallopian, or primary peritoneal cancer: a phase I, open-label, dose-escalation study.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158010

Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158010

Patupilone induced vascular disruption in orthotopic rodent tumor models detected by magnetic resonance imaging and interstitial fluid pressure

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158010

Attention and memory functioning among pediatric patients with medulloblastoma.

27 September 2018

1 reference

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Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs.

27 September 2018

1 reference

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Treatment of children with medulloblastomas with reduced-dose craniospinal radiation therapy and adjuvant chemotherapy: A Children's Cancer Group Study.

27 September 2018

1 reference

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Neurobehavioral and Neurologic Outcome in Long-Term Survivors of Posterior Fossa Brain Tumors: Role of Age and Perioperative Factors

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158010

27 September 2018

Identifiers

DOI

10.1093/NEUONC/NOR069

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6 August 2017

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6 August 2017

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