Hyperhomocysteinemia increases permeability of the blood-brain barrier by NMDA receptor-dependent regulation of adherens and tight junctions (Q35172510)

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English	Hyperhomocysteinemia increases permeability of the blood-brain barrier by NMDA receptor-dependent regulation of adherens and tight junctions	scientific article

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scholarly article

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Europe PubMed Central

6 August 2017

Hyperhomocysteinemia increases permeability of the blood-brain barrier by NMDA receptor-dependent regulation of adherens and tight junctions (English)

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Europe PubMed Central

6 August 2017

blood–brain barrier

1 reference

based on heuristic

inferred from title

author name string

Richard S Beard

1

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Europe PubMed Central

6 August 2017

Jason J Reynolds

2

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Europe PubMed Central

6 August 2017

Shawn E Bearden

3

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Europe PubMed Central

6 August 2017

language of work or name

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publication date

24 June 2011

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Europe PubMed Central

6 August 2017

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Europe PubMed Central

6 August 2017

118

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Europe PubMed Central

6 August 2017

2007-2014

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Europe PubMed Central

6 August 2017

7

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Europe PubMed Central

6 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3158726/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Effects of NMDA receptor modulators on a blood-brain barrier in vitro model.

1 reference

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13 July 2018

Vascular complications of cystathionine β-synthase deficiency: future directions for homocysteine-to-hydrogen sulfide research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Blood-brain barrier and cerebral small vessel disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Extracellular transsulfuration generates hydrogen sulfide from homocysteine and protects endothelium from redox stress

1 reference

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13 July 2018

The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis

1 reference

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13 July 2018

Glutamate receptors, neurotoxicity and neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Coupling of the NMDA receptor to neuroprotective and neurodestructive events

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13 July 2018

Oxidative stress upregulates the NMDA receptor on cerebrovascular endothelium

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13 July 2018

VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

The blood-brain barrier in brain homeostasis and neurological diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Wnt/beta-catenin signaling controls development of the blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Diabetes, cognitive function, and the blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Murine models of hyperhomocysteinemia and their vascular phenotypes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Association of plasma total homocysteine levels with subclinical brain injury: cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study

1 reference

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13 July 2018

Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation

1 reference

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13 July 2018

NMDA-receptor activation induces calpain-mediated beta-catenin cleavages for triggering gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond

1 reference

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13 July 2018

Homocysteine causes cerebrovascular leakage in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Elevated levels of homocysteine compromise blood-brain barrier integrity in mice

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Total homocysteine is associated with white matter hyperintensity volume: the Northern Manhattan Study

1 reference

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13 July 2018

Human Neuroepithelial Cells Express NMDA Receptors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Structure of cerebral arterioles in cystathionine beta-synthase-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Homocysteine, silent brain infarcts, and white matter lesions: The Rotterdam Scan Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Pores in the wall: claudins constitute tight junction strands containing aqueous pores

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Neuroprotective concentrations of the N-methyl-D-aspartate open-channel blocker memantine are effective without cytoplasmic vacuolation following post-ischemic administration and do not block maze learning or long-term potentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Fluorescein spectrophotofluorometry: a sensitive quantitative method for evaluating the blood brain barrier.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Fine structural localization of a blood-brain barrier to exogenous peroxidase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

13 July 2018

Effects of blockade of ionotropic glutamate receptors on blood-brain barrier disruption in focal cerebral ischemia

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27 September 2018

The NR1 subunit of NMDA receptor regulates monocyte transmigration through the brain endothelial cell barrier

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

27 September 2018

Blood-brain barrier permeability is increased in normal-appearing white matter in patients with lacunar stroke and leucoaraiosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

27 September 2018

Lacunar stroke is associated with diffuse blood-brain barrier dysfunction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

27 September 2018

Homocysteine and its relationship to stroke subtypes in a UK black population: the south London ethnicity and stroke study

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

27 September 2018

mRNA expression levels of tight junction protein genes in mouse brain capillary endothelial cells highly purified by magnetic cell sorting.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

27 September 2018

The NMDA and AMPA/KA receptors are involved in glutamate-induced alterations of occludin expression and phosphorylation in brain endothelial cells.

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27 September 2018

Identification of a homocysteine receptor in the peripheral endothelium and its role in proliferation

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27 September 2018

Memantine improves spatial learning in a transgenic mouse model of Alzheimer's disease.

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27 September 2018

Cerebral vascular dysfunction mediated by superoxide in hyperhomocysteinemic mice.

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27 September 2018

Serum total homocysteine concentrations and risk of stroke and its subtypes in Japanese

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27 September 2018

Transference of recombinant VE-cadherin cytoplasmic domain alters endothelial junctional integrity and porcine microvascular permeability.

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27 September 2018

Homocysteine is a risk factor for cerebral small vessel disease, acting via endothelial dysfunction

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158726

27 September 2018

Glutamate causes a loss in human cerebral endothelial barrier integrity through activation of NMDA receptor

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27 September 2018

Vitamin B12-B6-folate treatment improves blood-brain barrier function in patients with hyperhomocysteinaemia and mild cognitive impairment

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27 September 2018

Modulation of blood-brain barrier dysfunction and neurological deficits during acute experimental allergic encephalomyelitis by the N-methyl-D-aspartate receptor antagonist memantine

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27 September 2018

Association of plasma homocysteine concentration with atherosclerotic carotid plaques and lacunar infarction

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Expression of glutamate receptors on cultured cerebral endothelial cells.

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Reduction of edema and infarction by Memantine and MK-801 after focal cerebral ischaemia and reperfusion in rat

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12 December 2020

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10.1182/BLOOD-2011-02-338269

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Europe PubMed Central

6 August 2017

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Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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