Resistance to the translation initiation inhibitor silvestrol is mediated by ABCB1/P-glycoprotein overexpression in acute lymphoblastic leukemia cells (Q35176904)

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English	Resistance to the translation initiation inhibitor silvestrol is mediated by ABCB1/P-glycoprotein overexpression in acute lymphoblastic leukemia cells	scientific article

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scholarly article

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Europe PubMed Central

6 August 2017

Resistance to the translation initiation inhibitor silvestrol is mediated by ABCB1/P-glycoprotein overexpression in acute lymphoblastic leukemia cells (English)

1 reference

Europe PubMed Central

6 August 2017

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based on heuristic

inferred from title

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based on heuristic

inferred from title

lymphoblastic leukemia

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based on heuristic

inferred from title

10

object named as

John C Byrd

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Europe PubMed Central

6 August 2017

6

object named as

Nyla A Heerema

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Europe PubMed Central

6 August 2017

Michael R Grever

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object named as

Michael R Grever

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Europe PubMed Central

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object named as

Mitch A Phelps

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Europe PubMed Central

6 August 2017

Gerard Lozanski

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object named as

Gerard Lozanski

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Europe PubMed Central

6 August 2017

Melanie L Davis

3

object named as

Melanie E Davis

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Europe PubMed Central

6 August 2017

9

object named as

David Jarjoura

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Europe PubMed Central

6 August 2017

7

object named as

Amy Lehman

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Europe PubMed Central

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1

object named as

Sneha V Gupta

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Europe PubMed Central

6 August 2017

author name string

Ellen J Sass

2

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Europe PubMed Central

6 August 2017

Ryan B Edwards

4

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Europe PubMed Central

6 August 2017

Xiaoli Zhang

8

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Europe PubMed Central

6 August 2017

Li Pan

11

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Europe PubMed Central

6 August 2017

Kenneth K Chan

12

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Europe PubMed Central

6 August 2017

A Douglas Kinghorn

13

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Europe PubMed Central

6 August 2017

David M Lucas

16

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Europe PubMed Central

6 August 2017

language of work or name

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publication date

4 May 2011

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Europe PubMed Central

6 August 2017

The AAPS Journal

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Europe PubMed Central

6 August 2017

13

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Europe PubMed Central

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3

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Europe PubMed Central

6 August 2017

357-364

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Europe PubMed Central

6 August 2017

https://scigraph.springernature.com/pub.10.1208/s12248-011-9276-7

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Dissecting the role of mTOR: lessons from mTOR inhibitors

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13 July 2018

Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

Translation initiation: a critical signalling node in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

Optimal targeting of the mTORC1 kinase in human cancer

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13 July 2018

The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

Silvestrol, a potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

Mcl-1 is a relevant therapeutic target in acute and chronic lymphoid malignancies: down-regulation enhances rituximab-mediated apoptosis and complement-dependent cytotoxicity

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13 July 2018

Prognostic significance of multidrug resistance-related proteins in childhood acute lymphoblastic leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

Chemoresistance to depsipeptide FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)-ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8,7,6]-tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible MDR1 induction in human cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

Efflux of depsipeptide FK228 (FR901228, NSC-630176) is mediated by P-glycoprotein and multidrug resistance-associated protein 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

MDR1, chemotherapy and chromatin remodeling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

Signalling pathways influencing basal and H2O2‐induced P‐glycoprotein expression in endothelial cells derived from the blood–brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

Translation initiation in cancer: a novel target for therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

Translational control of malignancy: the mRNA cap-binding protein, eIF-4E, as a central regulator of tumor formation, growth, invasion and metastasis

1 reference

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13 July 2018

Arsenic induces apoptosis of multidrug-resistant human myeloid leukemia cells that express Bcr-Abl or overexpress MDR, MRP, Bcl-2, or Bcl-x(L)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

Up-regulation of multidrug resistance P-glycoprotein via nuclear factor-kappaB activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosis

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13 July 2018

Upregulation of protein synthesis initiation factor eIF-4E is an early event during colon carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

Altered methylation of the human MDR1 promoter is associated with acquired multidrug resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

Quantification of P-glycoprotein in chronic lymphocytic leukemia by flow cytometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3160166

13 July 2018

Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute drug screen.

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Generation of a drug resistance profile by quantitation of mdr-1/P-glycoprotein in the cell lines of the National Cancer Institute Anticancer Drug Screen

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Two new acute lymphoblastic leukemia cell lines with early B-cell phenotypes

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Localization of the human multiple drug resistance gene, MDR1, to 7q21.1

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ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells

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Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

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27 September 2018

Silvestrol regulates G2/M checkpoint genes independent of p53 activity.

1 reference

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27 September 2018

Depsipeptide (FR901228) induces histone acetylation and inhibition of histone deacetylase in chronic lymphocytic leukemia cells concurrent with activation of caspase 8-mediated apoptosis and down-regulation of c-FLIP protein

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12 December 2020

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10.1208/S12248-011-9276-7

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Europe PubMed Central

6 August 2017

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Europe PubMed Central

6 August 2017

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Europe PubMed Central

6 August 2017

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