Translation initiation: a critical signalling node in cancer (Q37586472)

21 August 2017

1 reference

title

Translation initiation: a critical signalling node in cancer (English)

1 reference

21 August 2017

Francis Robert

1

1 reference

PubMed ID

19705976

21 August 2017

Jerry Pelletier

series ordinal

2

1 reference

PubMed ID

19705976

21 August 2017

language of work or name

English

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publication date

1 November 2009

1 reference

Expert Opinion on Therapeutic Targets

21 August 2017

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21 August 2017

13

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21 August 2017

11

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21 August 2017

1279-1293

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21 August 2017

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The genomic landscapes of human breast and colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Comparative lesion sequencing provides insights into tumor evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Cancer risks among BRCA1 and BRCA2 mutation carriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Targeting the mTOR signaling network for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Dissociation of double-stranded polynucleotide helical structures by eukaryotic initiation factors, as revealed by a novel assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

A region rich in aspartic acid, arginine, tyrosine, and glycine (DRYG) mediates eukaryotic initiation factor 4B (eIF4B) self-association and interaction with eIF3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The expression of proto-oncogene eIF4E in laryngeal squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Prospective study of eukaryotic initiation factor 4E protein elevation and breast cancer outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Progression of eIF4e gene amplification and overexpression in benign and malignant tumors of the head and neck.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Expression of the eukaryotic translation initiation factors 4E and 2alpha in non-Hodgkin's lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Upregulation of protein synthesis initiation factor eIF-4E is an early event during colon carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Combined analysis of eIF4E and 4E-binding protein expression predicts breast cancer survival and estimates eIF4E activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

4E-binding protein 1: a key molecular "funnel factor" in human cancer with clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Translational control of programmed cell death: eukaryotic translation initiation factor 4E blocks apoptosis in growth-factor-restricted fibroblasts with physiologically expressed or deregulated Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Translation factor eIF4E rescues cells from Myc-dependent apoptosis by inhibiting cytochrome c release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Ras, PI(3)K and mTOR signalling controls tumour cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Ras mediates translation initiation factor 4E-induced malignant transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Translational control of the antiapoptotic function of Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Hyperactivation of protein kinase B and ERK have discrete effects on survival, proliferation, and cytokine expression in Nf1-deficient myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

TORC1 is essential for NF1-associated malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The NF1 tumor suppressor critically regulates TSC2 and mTOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Transcriptional regulation by MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The role of c-myc in cellular growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The role of c-myc in regulation of translation initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

An essential E box in the promoter of the gene encoding the mRNA cap-binding protein (eukaryotic initiation factor 4E) is a target for activation by c-myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

c-Myc and eIF4F are components of a feedforward loop that links transcription and translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Transcription-independent functions of MYC: regulation of translation and DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Translational control and metastatic progression: enhanced activity of the mRNA cap-binding protein eIF-4E selectively enhances translation of metastasis-related mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Phosphorylation of the cap-binding protein eIF4E by the MAPK-activated protein kinase Mnk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Chromatographic resolution of in vivo phosphorylated and nonphosphorylated eukaryotic translation initiation factor eIF-4E: increased cap affinity of the phosphorylated form

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Dissecting eIF4E action in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

TGF-beta-induced epithelial to mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Cell size and invasion in TGF-beta-induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Raptor-rictor axis in TGFbeta-induced protein synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Expression profiling of epithelial plasticity in tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The Wnt signaling pathway in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Wnt and beyond Wnt: multiple mechanisms control the transcriptional property of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The tuberin-hamartin complex negatively regulates beta-catenin signaling activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Active Src elevates the expression of beta-catenin by enhancement of cap-dependent translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Notch signaling: cell fate control and signal integration in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Activated Notch1 inhibits p53-induced apoptosis and sustains transformation by human papillomavirus type 16 E6 and E7 oncogenes through a PI3K-PKB/Akt-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Notch signalling regulates stem cell numbers in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Opposite effects of Notch-1 and Notch-2 on mesothelioma cell survival under hypoxia are exerted through the Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Missing pieces in the NF-kappaB puzzle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Transcriptional regulation of PIK3CA oncogene by NF-kappaB in ovarian cancer microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Regulation of mammalian target of rapamycin activity in PTEN-inactive prostate cancer cells by I kappa B kinase alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-kappaB activation and cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Protein kinase C-delta and phosphatidylinositol 3-kinase/Akt activate mammalian target of rapamycin to modulate NF-kappaB activation and intercellular adhesion molecule-1 (ICAM-1) expression in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The biochemistry of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Mechanisms and consequences of activation of protein kinase B/Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

PI3K: downstream AKTion blocks apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Translational regulation in cell stress and apoptosis. Roles of the eIF4E binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Lost in translation: dysregulation of cap-dependent translation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Life, death and E2F: linking proliferation control and DNA damage signaling via E2F1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

mTORC1 promotes survival through translational control of Mcl-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Tumorigenic activity and therapeutic inhibition of Rheb GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Targeting AKT signaling sensitizes cancer to cellular immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Interleukin-6 contributes to Mcl-1 up-regulation and TRAIL resistance via an Akt-signaling pathway in cholangiocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The anti-apoptotic role of interleukin-6 in human cervical cancer is mediated by up-regulation of Mcl-1 through a PI 3-K/Akt pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The phosphotidyl inositol 3-kinase/Akt signal pathway is involved in interleukin-6-mediated Mcl-1 upregulation and anti-apoptosis activity in basal cell carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Over-expression of interleukin-6 enhances cell survival and transformed cell growth in human malignant cholangiocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Inhibition of mTOR enhances chemosensitivity in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The dual PI3 kinase/mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Inhibition of mTOR restores cisplatin sensitivity through down-regulation of growth and anti-apoptotic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Translation initiation factor 4E blocks endoplasmic reticulum-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Met acts on Mdm2 via mTOR to signal cell survival during development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

eIF4E is a central node of an RNA regulon that governs cellular proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

MNK1 and EIF4E are downstream effectors of MEKs in the regulation of the nuclear export of HDM2 mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

p53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

IAP-targeted therapies for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Targeting inhibitor of apoptosis proteins (IAPs) for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Tumor resistance to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Tumor-specific RNAi targeting eIF4E suppresses tumor growth, induces apoptosis and enhances cisplatin cytotoxicity in human breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

IL-6 activates serum and glucocorticoid kinase via p38alpha mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Translational regulation of x-linked inhibitor of apoptosis protein by interleukin-6: a novel mechanism of tumor cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

CCL2, survivin and autophagy: new links with implications in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

BCR/ABL and other kinases from chronic myeloproliferative disorders stimulate single-strand annealing, an unfaithful DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Cell cycle, CDKs and cancer: a changing paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

TOR, a central controller of cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Eukaryotic translation initiation factor 4E regulates expression of cyclin D1 at transcriptional and post-transcriptional levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

eIF4E knockdown decreases breast cancer cell growth without activating Akt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Growth inhibition of head and neck squamous carcinoma cells by small interfering RNAs targeting eIF4E or cyclin D1 alone or combined with cisplatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

UVA-induced cell cycle progression is mediated by a disintegrin and metalloprotease/epidermal growth factor receptor/AKT/Cyclin D1 pathways in keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Regulation of cyclin D1 expression by mTORC1 signaling requires eukaryotic initiation factor 4E-binding protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Heterogeneous nuclear ribonucleoprotein A1 regulates cyclin D1 and c-myc internal ribosome entry site function through Akt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

LY294002 and rapamycin co-operate to inhibit T-cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

mTORC1 activation regulates beta-cell mass and proliferation by modulation of cyclin D2 synthesis and stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Evidence for cyclin D3 as a novel target of rapamycin in human T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Cyclin D3 is down-regulated by rapamycin in HER-2-overexpressing breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Rapamycin inhibits human renal epithelial cell proliferation: effect on cyclin D3 mRNA expression and stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Negative regulation of TSC1-TSC2 by mammalian D-type cyclins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Expression of constitutively active 4EBP-1 enhances p27Kip1 expression and inhibits proliferation of MCF7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The DNA damage response pathways: at the crossroad of protein modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

DNA damage checkpoints and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

DNA-damaging agents cause inactivation of translational regulators linked to mTOR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Chromium(III) triggers the DNA-damaged checkpoint of the cell cycle and induces a functional increase of 4E-BP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Hypoxia and DNA-damaging agent bleomycin both increase the cellular level of the protein 4E-BP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Translational regulation of ribonucleotide reductase by eukaryotic initiation factor 4E links protein synthesis to the control of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

A translationally regulated Tousled kinase phosphorylates histone H3 and confers radioresistance when overexpressed

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The radioresistance kinase TLK1B protects the cells by promoting repair of double strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

TLK1B promotes repair of UV-damaged DNA through chromatin remodeling by Asf1

21 January 2018

1 reference

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Cadherins in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Cadherins and catenins in breast cancer

21 January 2018

1 reference

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Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions. Evidence for the association of phosphatidylinositol 3-kinase with the E-cadherin adhesion complex.

21 January 2018

1 reference

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Roles of phosphatidylinositol 3'-kinase and mammalian target of rapamycin/p70 ribosomal protein S6 kinase in K-Ras-mediated transformation of intestinal epithelial cells

21 January 2018

1 reference

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Integrins: versatility, modulation, and signaling in cell adhesion

21 January 2018

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Roles of integrins in tumor angiogenesis and lymphangiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Integrin-dependent translational control: Implication in cancer progression

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903241625

Integrin-dependent activation of the p70 ribosomal S6 kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Association of focal adhesion kinase with tuberous sclerosis complex 2 in the regulation of s6 kinase activation and cell growth

21 January 2018

1 reference

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Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival

21 January 2018

1 reference

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Progress in matrix metalloproteinase research

21 January 2018

1 reference

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Extracellular matrix proteases - cytokine regulation role in cancer and pregnancy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The ADAMs: signalling scissors in the tumour microenvironment

21 January 2018

1 reference

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Meprin metalloprotease expression and regulation in kidney, intestine, urinary tract infections and cancer.

21 January 2018

1 reference

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VEGF and the quest for tumour angiogenesis factors

21 January 2018

1 reference

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Vascular endothelial growth factor signaling pathways: therapeutic perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Akt mediates an angiogenic switch in transformed keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

ADAM17 promotes breast cancer cell malignant phenotype through EGFR-PI3K-AKT activation

21 January 2018

1 reference

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Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab

21 January 2018

1 reference

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Vascular endothelial growth factor: basic science and clinical progress

21 January 2018

1 reference

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CXCR6 induces prostate cancer progression by the AKT/mammalian target of rapamycin signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

RANTES: a versatile and controversial chemokine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

The unexpected pleiotropic activities of RANTES.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

CCL5 increases lung cancer migration via PI3K, Akt and NF-kappaB pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

CCL5/CCR5 axis promotes the motility of human oral cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

eIF4E activation is commonly elevated in advanced human prostate cancers and significantly related to reduced patient survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903241625

Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells

21 January 2018

1 reference

3 January 2024

https://opencitations.net/index/api/v1/citations/10.1158/0008-5472.CAN-05-4281

Identifiers

DOI

10.1517/14728220903241625

1 reference

21 August 2017

1 reference

PubMed ID

19705976