A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport (Q35182991)

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English	A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport	scientific article

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6 February 2020

A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport (English)

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6 February 2020

transmembrane transport

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transmembrane protein

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neurotransmitter

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inferred from title

16

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6 February 2020

Sergei Y Noskov

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Louis J. De Felice

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L Keith Henry

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Hideki Iwamoto

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Julie R Field

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Kristian Kaufmann

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Eric S Dawson

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Miriam T Jacobs

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Chelsea Adams

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Bruce Felts

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Igor Zdravkovic

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6 February 2020

Vanessa Armstrong

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Steven Combs

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6 February 2020

Gary Rudnick

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Randy D Blakely

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5 July 2011

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Journal of Biological Chemistry

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6 February 2020

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6 February 2020

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6 February 2020

30823-30836

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6 February 2020

The mechanism of sodium and substrate release from the binding pocket of vSGLT

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Reconstructing a chloride-binding site in a bacterial neurotransmitter transporter homologue

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A glutamine residue conserved in the neurotransmitter:sodium:symporters is essential for the interaction of chloride with the GABA transporter GAT-1

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Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1

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Transmembrane domain 6 of the human serotonin transporter contributes to an aqueously accessible binding pocket for serotonin and the psychostimulant 3,4-methylene dioxymethamphetamine

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Molecular basis of transport and regulation in the Na(+)/betaine symporter BetP

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Structural determinants of species-selective substrate recognition in human and Drosophila serotonin transporters revealed through computational docking studies

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The Crystal Structure of a Sodium Galactose Transporter Reveals Mechanistic Insights into Na+/Sugar Symport

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Contribution of the Na-K-Cl cotransporter on GABA(A) receptor-mediated presynaptic depolarization in excitatory nerve terminals.

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Interactions of tryptamine derivatives with serotonin transporter species variants implicate transmembrane domain I in substrate recognition

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Patch-clamp and amperometric recordings from norepinephrine transporters: channel activity and voltage-dependent uptake

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Amino acid residues that control pH modulation of transport-associated current in mammalian serotonin transporters.

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Single-channel currents produced by the serotonin transporter and analysis of a mutation affecting ion permeation

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A cocaine-sensitive Drosophila serotonin transporter: cloning, expression, and electrophysiological characterization

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Uptake of Serotonin in Blood Platelets in vitro. I: The Effects of Chloride

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Expression of mRNA (D2) encoding a protein involved in amino acid transport in S3 proximal tubule

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An [Na+ + K+]coupled L-glutamate transporter purified from rat brain is located in glial cell processes

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GABA efflux from synaptosomes: effects of membrane potential, and external GABA and cations

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21 January 2018

Serotonin transporter function and pharmacology are sensitive to expression level: evidence for an endogenous regulatory factor

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21 January 2018

Dopamine transporter-mediated conductances increase excitability of midbrain dopamine neurons.

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Serotonin and cocaine-sensitive inactivation of human serotonin transporters by methanethiosulfonates targeted to transmembrane domain I.

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21 January 2018

Ionic interactions in the Drosophila serotonin transporter identify it as a serotonin channel

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21 January 2018

Molecular mechanism of substrate specificity in the bacterial neutral amino acid transporter LeuT.

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21 January 2018

Evidence that NADP+ is the physiological cofactor of ADP-L-glycero-D-mannoheptose 6-epimerase

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21 January 2018

Structure and function of extracellular loop 4 of the serotonin transporter as revealed by cysteine-scanning mutagenesis

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21 January 2018

The cytoplasmic substrate permeation pathway of serotonin transporter

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21 January 2018

Conducting states of a mammalian serotonin transporter.

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21 January 2018

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21 January 2018

High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol

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21 January 2018

Potential of mean force and pKa profile calculation for a lipid membrane-exposed arginine side chain

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21 January 2018

Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport.

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21 January 2018

Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter.

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27 September 2018

Mechanism of Transport and Storage of Neurotransmitter

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21 January 2018

Stabilization of the Catalytic Thiolate in a Mammalian Glutaredoxin: Structure, Dynamics and Electrostatics of Reduced Pig Glutaredoxin and its Mutants

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21 January 2018

Determination of Electrostatic Parameters for a Polarizable Force Field Based on the Classical Drude Oscillator

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21 January 2018

A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function

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12 December 2020

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The role of chloride ion in platelet serotonin transport

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12 December 2020

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External cysteine residues in the serotonin transporter

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12 December 2020

based on heuristic

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10.1074/JBC.M111.250308

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6 February 2020

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6 February 2020

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6 February 2020

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