A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens. (Q35186717)

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7 February 2020

title

A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens (English)

1 reference

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7 February 2020

0 references

1 reference

9

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Ki-Bum Lee

10

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Shuang Hou

14

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R Michael van Dam

26

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Linda Liau

29

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Thomas Graeber

34

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Harley I Kornblum

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7 February 2020

author name string

Jing Sun

1

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7 February 2020

Michael D Masterman-Smith

2

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7 February 2020

Nicholas A Graham

3

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7 February 2020

Jing Jiao

4

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7 February 2020

Jack Mottahedeh

5

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7 February 2020

Dan R Laks

6

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Minori Ohashi

7

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Jason DeJesus

8

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7 February 2020

Hao Wang

11

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Zeta T F Yu

12

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Yi-Tsung Lu

13

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Keyu Li

15

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7 February 2020

Max Liu

16

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7 February 2020

Nangang Zhang

17

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Brigitte Angenieux

19

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Eduard Panosyan

20

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Eric R Samuels

21

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Jun Park

22

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7 February 2020

Dirk Williams

23

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Vera Konkankit

24

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David Nathanson

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Michael E Phelps

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Hong Wu

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Paul S Mischel

30

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Jorge A Lazareff

31

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William H Yong

33

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Hsian-Rong Tseng

35

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Shutao Wang

18

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7 February 2020

language of work or name

English

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publication date

14 July 2010

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7 February 2020

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7 February 2020

volume

70

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7 February 2020

issue

15

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7 February 2020

page(s)

6128-6138

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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

7 February 2020

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Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations

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Neurosphere formation is an independent predictor of clinical outcome in malignant glioma

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Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis

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Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma

13 July 2018

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Malignant astrocytic glioma: genetics, biology, and paths to treatment

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Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma

13 July 2018

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Microfluidic chips for detecting the t(4;14) translocation and monitoring disease during treatment using reverse transcriptase-polymerase chain reaction analysis of IgH-MMSET hybrid transcripts

13 July 2018

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13 July 2018

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Single-cell quantification of molecules and rates using open-source microscope-based cytometry

13 July 2018

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Counting low-copy number proteins in a single cell

13 July 2018

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Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells

13 July 2018

1 reference

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The role of companion diagnostics in the development and use of mutation-targeted cancer therapies

13 July 2018

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13 July 2018

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Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling

13 July 2018

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Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

13 July 2018

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Assessment of the HER2 status in breast cancer by fluorescence in situ hybridization: a technical review with interpretive guidelines

13 July 2018

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DNA-microarray analysis of brain cancer: molecular classification for therapy

13 July 2018

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Single cell profiling of potentiated phospho-protein networks in cancer cells.

13 July 2018

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13 July 2018

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Cancerous stem cells can arise from pediatric brain tumors

13 July 2018

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PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

13 July 2018

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Clustering of the SOM easily reveals distinct gene expression patterns: results of a reanalysis of lymphoma study

13 July 2018

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Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry

13 July 2018

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Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation

13 July 2018

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Cluster analysis and display of genome-wide expression patterns

13 July 2018

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Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails

13 July 2018

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An integrated microfluidic culture device for quantitative analysis of human embryonic stem cells

13 July 2018

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Mapping normal and cancer cell signalling networks: towards single-cell proteomics

27 September 2018

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Predominant expression of mutant EGFR (EGFRvIII) is rare in primary glioblastomas

27 September 2018

1 reference

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Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events

27 September 2018

1 reference

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Analysis of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma patients in vivo

27 September 2018

1 reference

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Influence of unrecognized molecular heterogeneity on randomized clinical trials

27 September 2018

1 reference

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Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival.

27 September 2018

1 reference

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PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme.

27 September 2018

1 reference

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10.1158/0008-5472.CAN-10-0076

27 September 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20631065%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20631065%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

20631065

1 reference