Brain insulin action augments hepatic glycogen synthesis without suppressing glucose production or gluconeogenesis in dogs. (Q35187061)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21865644%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Brain insulin action augments hepatic glycogen synthesis without suppressing glucose production or gluconeogenesis in dogs (English)

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11 February 2020

1 reference

1 reference

Christopher J Ramnanan

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Dale S Edgerton

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Alan D Cherrington

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Tiffany D Farmer

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Ben Farmer

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11 February 2020

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Marta S Smith

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11 February 2020

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Doss Neal

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11 February 2020

author name string

Viswanathan Saraswathi

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11 February 2020

E Patrick Donahue

4

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11 February 2020

Philip E Williams

8

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Margaret Lautz

9

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Andrea Mari

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11 February 2020

language of work or name

English

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publication date

25 August 2011

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Journal of Clinical Investigation

11 February 2020

published in

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volume

121

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issue

9

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11 February 2020

page(s)

3713-3723

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Brain insulin controls adipose tissue lipolysis and lipogenesis

11 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Influence of insulin in the ventromedial hypothalamus on pancreatic glucagon secretion in vivo

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Molecular characterization of insulin-mediated suppression of hepatic glucose production in vivo

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

The hypothalamus bridges the gap between physiology and biochemistry in high-fat diet-induced hepatic insulin resistance

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Hypothalamic leptin signaling regulates hepatic insulin sensitivity via a neurocircuit involving the vagus nerve

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Targeting the CNS to treat type 2 diabetes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Regulation of hepatic glucose production and the role of gluconeogenesis in humans: is the rate of gluconeogenesis constant?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Function and expression of somatostatin receptors of the endocrine pancreas

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Insulin action on the liver in vivo

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Cytosolic phosphoenolpyruvate carboxykinase does not solely control the rate of hepatic gluconeogenesis in the intact mouse liver

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Insulin's direct effects on the liver dominate the control of hepatic glucose production

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

A brain-liver circuit regulates glucose homeostasis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Hypothalamic K(ATP) channels control hepatic glucose production

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Impaired tricarboxylic acid cycle activity in mouse livers lacking cytosolic phosphoenolpyruvate carboxykinase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Banting Lecture 1997. Control of glucose uptake and release by the liver in vivo

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Ethanol is a potent inhibitor of canine cerebrospinal fluid production: an acute and reversible effect

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Indirect effect of insulin to suppress endogenous glucose production is dominant, even with hyperglucagonemia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Regulation of glucose homeostasis in humans with denervated livers

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

New concepts in extracellular signaling for insulin action: the single gateway hypothesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Role of glucagon in maintenance of euglycemia in fed and fasted rats.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Neural control of the endocrine pancreas

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Effect of hyperglucagonemia on hepatic glycogenolysis and gluconeogenesis after a prolonged fast.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Effect of Cerebral Intraventricular Insulin on Pancreatic Insulin Secretion in the Dog

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Evidence for an important role of glucagon in the regulation of hepatic glucose production in normal man.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Control of hepatic glucose output by glucagon and insulin in the intact dog

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Concentrations of insulin and insulin receptors in the brain are independent of peripheral insulin levels. Studies of obese and streptozotocin-treated rodents

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Changes of glycogen content in liver, skeletal muscle, and heart from fasted rats

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Long-term intracerebroventricular infusion of insulin, but not glucose, modulates body weight and hepatic insulin sensitivity by modifying the hypothalamic insulin signaling pathway in type 2 diabetic rats

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

STAT3 sensitizes insulin signaling by negatively regulating glycogen synthase kinase-3 beta.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Role of hepatic STAT3 in brain-insulin action on hepatic glucose production

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Regulation of blood glucose by hypothalamic pyruvate metabolism

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

A circulatory model for calculating non-steady-state glucose fluxes. Validation and comparison with compartmental models

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Hypothalamic insulin signaling is required for inhibition of glucose production

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

Effect of hepatic denervation on peripheral insulin sensitivity in conscious dogs

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163950

The role of fatty acids in mediating the effects of peripheral insulin on hepatic glucose production in the conscious dog

27 September 2018

1 reference

12 December 2020

A comparison of the effects of selective increases in peripheral or portal insulin on hepatic glucose production in the conscious dog

1 reference

12 December 2020

Rapid Activation-Inactivation of Liver Uridine Diphosphate Glucose-Glycogen Transferase and Phosphorylase by Insulin and Glucagon in Vivo

1 reference

12 December 2020

Disposition of a mixed meal by the conscious dog

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI45472

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21865644%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21865644%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

21865644

1 reference