Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action (Q33768316)

29 July 2017

Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action (English)

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29 July 2017

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3

Domenico Accili

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29 July 2017

Haruka Okamoto

1

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29 July 2017

Silvana Obici

series ordinal

2

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29 July 2017

Luciano Rossetti

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4

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29 July 2017

language of work or name

English

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publication date

1 May 2005

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Journal of Clinical Investigation

29 July 2017

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29 July 2017

115

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29 July 2017

5

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29 July 2017

1314-1322

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describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1087162/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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22 June 2018

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22 June 2018

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Targeted disruption of the insulin receptor gene in the mouse results in neonatal lethality

22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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30 October 2018

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30 October 2018

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Hypothalamic insulin signaling is required for inhibition of glucose production

30 October 2018

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30 October 2018

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Selective tonic inhibition of G-6-Pase catalytic subunit, but not G-6-P transporter, gene expression by insulin in vivo

30 October 2018

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Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

30 October 2018

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Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue.

30 October 2018

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Basal hepatic glucose production is regulated by the portal vein insulin concentration.

30 October 2018

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Role of glucokinase and glucose-6-phosphatase in the acute and chronic regulation of hepatic glucose fluxes by insulin.

30 October 2018

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Early neonatal death in mice homozygous for a null allele of the insulin receptor gene

30 October 2018

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12 December 2020

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

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12 December 2020

Hepatic overexpression of insulin-like growth factor-II in adulthood increases basal and insulin-stimulated glucose disposal in conscious mice

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12 December 2020

Quantitation of hepatic glucose fluxes and pathways of hepatic glycogen synthesis in conscious mice

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12 December 2020

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles

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12 December 2020

Fatty acids mediate the acute extrahepatic effects of insulin on hepatic glucose production in humans

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12 December 2020

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

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12 December 2020

Identifiers

DOI

10.1172/JCI200523096

1 reference

29 July 2017

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29 July 2017

1 reference