Gsα enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice. (Q35187105)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21804192%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Gsα enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice (English)

1 reference

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9 February 2020

0 references

9

1 reference

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9 February 2020

Natalie A. Sims

10

1 reference

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9 February 2020

3

Murat Bastepe

1 reference

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9 February 2020

author name string

Joy Y Wu

1

1 reference

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9 February 2020

Piia Aarnisalo

2

1 reference

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9 February 2020

Partha Sinha

4

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9 February 2020

Keertik Fulzele

5

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9 February 2020

Martin K Selig

6

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9 February 2020

Min Chen

7

1 reference

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9 February 2020

Ingrid J Poulton

8

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9 February 2020

Lee S Weinstein

11

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9 February 2020

Henry M Kronenberg

12

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9 February 2020

language of work or name

English

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publication date

1 August 2011

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Journal of Clinical Investigation

9 February 2020

published in

1 reference

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9 February 2020

volume

121

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9 February 2020

issue

9

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9 February 2020

page(s)

3492-3504

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Targeted overexpression of Dkk1 in osteoblasts reduces bone mass but does not impair the anabolic response to intermittent PTH treatment in mice

9 February 2020

cites work

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Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis

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Suppression of Wnt signaling by Dkk1 attenuates PTH-mediated stromal cell response and new bone formation

13 July 2018

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Extralarge XL(alpha)s (XXL(alpha)s), a variant of stimulatory G protein alpha-subunit (Gs(alpha)), is a distinct, membrane-anchored GNAS product that can mimic Gs(alpha).

13 July 2018

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Intermittent PTH stimulates periosteal bone formation by actions on post-mitotic preosteoblasts

13 July 2018

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Parathyroid hormone signaling through low-density lipoprotein-related protein 6

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Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways

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Time lapse imaging techniques for comparison of mineralization dynamics in primary murine osteoblasts and the late osteoblast/early osteocyte-like cell line MLO-A5.

13 July 2018

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Control of bone mass and remodeling by PTH receptor signaling in osteocytes

13 July 2018

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Osteocytes, mechanosensing and Wnt signaling

13 July 2018

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Osteoblast expression of an engineered Gs-coupled receptor dramatically increases bone mass

13 July 2018

1 reference

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CBP/p300-interacting protein CITED1 modulates parathyroid hormone regulation of osteoblastic differentiation

13 July 2018

1 reference

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Control of the SOST bone enhancer by PTH using MEF2 transcription factors

13 July 2018

1 reference

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Molecular and cellular mechanisms of the anabolic effect of intermittent PTH

13 July 2018

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SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation

13 July 2018

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E11/gp38 selective expression in osteocytes: regulation by mechanical strain and role in dendrite elongation

13 July 2018

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Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia

13 July 2018

1 reference

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Genetic diseases associated with heterotrimeric G proteins

13 July 2018

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Parathyroid hormone increases beta-catenin levels through Smad3 in mouse osteoblastic cells

13 July 2018

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Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase

13 July 2018

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13 July 2018

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Increased glucose tolerance and reduced adiposity in the absence of fasting hypoglycemia in mice with liver-specific Gs alpha deficiency

13 July 2018

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Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis

13 July 2018

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Effects of parathyroid hormone on Wnt signaling pathway in bone

13 July 2018

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SOST is a target gene for PTH in bone

13 July 2018

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Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation

13 July 2018

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Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis

13 July 2018

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Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

13 July 2018

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Essential role of beta-catenin in postnatal bone acquisition

13 July 2018

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Deficiency of the G-protein alpha-subunit G(s)alpha in osteoblasts leads to differential effects on trabecular and cortical bone

13 July 2018

1 reference

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Leptin regulation of bone resorption by the sympathetic nervous system and CART

13 July 2018

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Stimulatory G protein directly regulates hypertrophic differentiation of growth plate cartilage in vivo.

13 July 2018

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Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects

13 July 2018

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Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

13 July 2018

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Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair

13 July 2018

1 reference

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Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation

13 July 2018

1 reference

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Endocrine manifestations of stimulatory G protein alpha-subunit mutations and the role of genomic imprinting

13 July 2018

1 reference

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Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis

13 July 2018

1 reference

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Activated parathyroid hormone/parathyroid hormone-related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone

13 July 2018

1 reference

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Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis 1

13 July 2018

1 reference

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Activation of osteocalcin transcription involves interaction of protein kinase A- and protein kinase C-dependent pathways

13 July 2018

1 reference

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Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

13 July 2018

1 reference

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Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormone

13 July 2018

1 reference

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Generalized lacZ expression with the ROSA26 Cre reporter strain

13 July 2018

1 reference

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The parathyroid hormone/parathyroid hormone-related peptide receptor coordinates endochondral bone development by directly controlling chondrocyte differentiation

13 July 2018

1 reference

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Is all bone the same? Distinctive distributions and properties of non-collagenous matrix proteins in lamellar vs. woven bone imply the existence of different underlying osteogenic mechanisms

13 July 2018

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Parathyroid hormone regulates the rat collagenase-3 promoter in osteoblastic cells through the cooperative interaction of the activator protein-1 site and the runt domain binding sequence

13 July 2018

1 reference

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Reproduction of human fibrous dysplasia of bone in immunocompromised mice by transplanted mosaics of normal and Gsalpha-mutated skeletal progenitor cells.

13 July 2018

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Parathyroid hormone exerts disparate effects on osteoblast differentiation depending on exposure time in rat osteoblastic cells

13 July 2018

1 reference

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Parathyroid hormone induces c-fos promoter activity in osteoblastic cells through phosphorylated cAMP response element (CRE)-binding protein binding to the major CRE.

13 July 2018

1 reference

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PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth

13 July 2018

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Prostaglandin E receptor subtypes in mouse osteoblastic cell line

13 July 2018

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Cloned, stably expressed parathyroid hormone (PTH)/PTH-related peptide receptors activate multiple messenger signals and biological responses in LLC-PK1 kidney cells

13 July 2018

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A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia

13 July 2018

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PB76: a novel surface glycoprotein preferentially expressed on mouse pre-B cells and plasma cells detected by the monoclonal antibody G-5-2.

13 July 2018

1 reference

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Parathyroid hormone-related peptide represses chondrocyte hypertrophy through a protein phosphatase 2A/histone deacetylase 4/MEF2 pathway

13 July 2018

1 reference

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A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism

27 September 2018

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Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors.

27 September 2018

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Perinatal testosterone surge is required for normal adult bone size but not for normal bone remodeling.

27 September 2018

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Comparison of the action of transient and continuous PTH on primary osteoblast cultures expressing differentiation stage-specific GFP.

27 September 2018

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Use of type I collagen green fluorescent protein transgenes to identify subpopulations of cells at different stages of the osteoblast lineage.

27 September 2018

1 reference

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Osteoprogenitor cell frequency in rat bone marrow stromal populations: role for heterotypic cell-cell interactions in osteoblast differentiation

27 September 2018

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12 December 2020

Chondrocyte-specific knockout of the G protein G(s)alpha leads to epiphyseal and growth plate abnormalities and ectopic chondrocyte formation

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12 December 2020

Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction

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12 December 2020

The E11 osteoblastic lineage marker is differentially expressed during fracture healing

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12 December 2020

TSH Is a Negative Regulator of Skeletal Remodeling

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12 December 2020

Identifiers

DOI

10.1172/JCI46406

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21804192%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21804192%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference