Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation (Q35200617)

7 August 2017

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title

Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation (English)

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7 August 2017

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Lin-Feng Chen

1

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PubMed ID

12920522

7 August 2017

Warner C Greene

series ordinal

2

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7 August 2017

15 August 2003

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Journal of Molecular Medicine

7 August 2017

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7 August 2017

81

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7 August 2017

9

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7 August 2017

549-557

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https://scigraph.springernature.com/pub.10.1007/s00109-003-0469-0

7 August 2017

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cites work

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Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)

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Control of Smad7 stability by competition between acetylation and ubiquitination

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p65-NFkappaB synergizes with Notch to activate transcription by triggering cytoplasmic translocation of the nuclear receptor corepressor N-CoR.

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12 December 2020

The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase gcn5p

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Transcriptional activation by NF-kappaB requires multiple coactivators

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Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA

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12 December 2020

The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation

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12 December 2020

The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1

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12 December 2020

Interaction between acetylated MyoD and the bromodomain of CBP and/or p300

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12 December 2020

Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.

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12 December 2020

The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators

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12 December 2020

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

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12 December 2020

Silencing mediator of retinoic acid and thyroid hormone receptors, as a novel transcriptional corepressor molecule of activating protein-1, nuclear factor-kappaB, and serum response factor

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12 December 2020

Enhancement of nuclear factor-kappa B acetylation by coactivator p300 and HIV-1 Tat proteins.

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12 December 2020

Regulation of the homeodomain CCAAT displacement/cut protein function by histone acetyltransferases p300/CREB-binding protein (CBP)-associated factor and CBP

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12 December 2020

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

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12 December 2020

Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

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12 December 2020

Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain

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12 December 2020

Roles of histone acetyltransferases and deacetylases in gene regulation

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12 December 2020

Acetylation and chromosomal functions.

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12 December 2020

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

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12 December 2020

Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

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12 December 2020

Regulation of E2F1 activity by acetylation

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12 December 2020

Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes

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12 December 2020

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

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12 December 2020

The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter.

1 reference

12 December 2020

Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor kappaB-mediated transactivations

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12 December 2020

The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression

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12 December 2020

Acetylation control of the retinoblastoma tumour-suppressor protein

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12 December 2020

The NF-kappa B and I kappa B proteins: new discoveries and insights

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12 December 2020

The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

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12 December 2020

Gene activation by histone and factor acetyltransferases

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12 December 2020

Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase

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12 December 2020

CD40 regulates the processing of NF-kappaB2 p100 to p52

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12 December 2020

Structure and ligand of a histone acetyltransferase bromodomain

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12 December 2020

Acetylation of HMG I(Y) by CBP turns off IFN beta expression by disrupting the enhanceosome

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12 December 2020

Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A

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12 December 2020

Acetylation of general transcription factors by histone acetyltransferases

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12 December 2020

BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

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12 December 2020

Transcription factor-dependent regulation of CBP and P/CAF histone acetyltransferase activity

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12 December 2020

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

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12 December 2020

Acetylation of adenovirus E1A regulates binding of the transcriptional corepressor CtBP.

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12 December 2020

p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

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12 December 2020

DNA damage activates p53 through a phosphorylation-acetylation cascade

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12 December 2020

RAC-3 is a NF-kappa B coactivator

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12 December 2020

The IKK/NF-kappa B pathway

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12 December 2020

The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3

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12 December 2020

Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha

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12 December 2020

Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65

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12 December 2020

Acetylation of histones and transcription-related factors

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12 December 2020

Nuclear localization of I kappa B alpha promotes active transport of NF-kappa B from the nucleus to the cytoplasm.

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12 December 2020

Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein

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12 December 2020

IkappaBalpha and p65 regulate the cytoplasmic shuttling of nuclear corepressors: cross-talk between Notch and NFkappaB pathways

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12 December 2020

Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR

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12 December 2020

NF-kappaB in cancer: from innocent bystander to major culprit

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12 December 2020

IkappaB-NF-kappaB structures: at the interface of inflammation control

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12 December 2020

Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II

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12 December 2020

Duration of nuclear NF-kappaB action regulated by reversible acetylation

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12 December 2020

CREB-binding protein/p300 are transcriptional coactivators of p65

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12 December 2020

A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity

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12 December 2020

Regulation of activity of the transcription factor GATA-1 by acetylation

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12 December 2020

Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator

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12 December 2020

Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-kappaB and inhibitors of deacetylases: potential perspectives for the development of therapeutic strategies

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12 December 2020

HATs on and beyond chromatin

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12 December 2020

Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B.

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12 December 2020

Up-regulation of p300 binding and p50 acetylation in tumor necrosis factor-alpha-induced cyclooxygenase-2 promoter activation

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12 December 2020

The histone deacetylase-3 complex contains nuclear receptor corepressors

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12 December 2020

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

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12 December 2020

10.1007/S00109-003-0469-0

Identifiers

DOI

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7 August 2017

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PubMed ID

12920522