Prolyl peptidases: a serine protease subfamily with high potential for drug discovery. (Q35206949)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941425%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

review article

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title

Prolyl peptidases: a serine protease subfamily with high potential for drug discovery (English)

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7 November 2019

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1

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7 November 2019

author name string

John W Kozarich

series ordinal

2

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7 November 2019

publication date

1 August 2003

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Current Opinion in Chemical Biology

7 November 2019

published in

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7 November 2019

volume

7

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7 November 2019

issue

4

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7 November 2019

page(s)

496-504

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Dipeptidyl peptidase IV substrates. An update on in vitro peptide hydrolysis by human DPPIV

7 November 2019

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Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog

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NVP-DPP728 (1-[[[2-[(5-cyanopyridin-2-yl)amino]ethyl]amino]acetyl]-2-cyano-(S)- pyrrolidine), a slow-binding inhibitor of dipeptidyl peptidase IV

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Inhibition of dipeptidyl peptidase IV improves metabolic control over a 4-week study period in type 2 diabetes

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Chronic inhibition of circulating dipeptidyl peptidase IV by FE 999011 delays the occurrence of diabetes in male zucker diabetic fatty rats

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Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice

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7 January 2021

Long-term treatment with the dipeptidyl peptidase IV inhibitor P32/98 causes sustained improvements in glucose tolerance, insulin sensitivity, hyperinsulinemia, and beta-cell glucose responsiveness in VDF (fa/fa) Zucker rats

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Long-term treatment with dipeptidyl peptidase IV inhibitor improves hepatic and peripheral insulin sensitivity in the VDF Zucker rat: a euglycemic-hyperinsulinemic clamp study

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Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats.

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Clustered charged amino acids of human adenosine deaminase comprise a functional epitope for binding the adenosine deaminase complexing protein CD26/dipeptidyl peptidase IV.

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Dipeptidyl peptidase IV expression in endometrial endometrioid adenocarcinoma and its inverse correlation with tumor grade

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Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts

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DPPIV and seprase in cancer invasion and angiogenesis

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Regulation of fibroblast migration on collagenous matrix by a cell surface peptidase complex

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Stromal antigen targeting by a humanised monoclonal antibody: an early phase II trial of sibrotuzumab in patients with metastatic colorectal cancer

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Hematopoietic stimulation by a dipeptidyl peptidase inhibitor reveals a novel regulatory mechanism and therapeutic treatment for blood cell deficiencies

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7 January 2021

Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8

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7 January 2021

Identification and characterization of human DPP9, a novel homologue of dipeptidyl peptidase IV

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Vesicular localization and characterization of a novel post-proline-cleaving aminodipeptidase, quiescent cell proline dipeptidase

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7 January 2021

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7 January 2021

Rump white inversion in the mouse disrupts dipeptidyl aminopeptidase-like protein 6 and causes dysregulation of Kit expression

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7 January 2021

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Attractin (DPPT-L), a member of the CUB family of cell adhesion and guidance proteins, is secreted by activated human T lymphocytes and modulates immune cell interactions

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7 January 2021

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12941425%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

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