Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation (Q35208373)

7 August 2017

Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation. (English)

1 reference

7 August 2017

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10

Michael Karin

1 reference

7 August 2017

6

Hilde Cheroutre

1 reference

7 August 2017

Monica Guma

1

1 reference

7 August 2017

Dariusz Stepniak

2

1 reference

7 August 2017

Helena Shaked

3

1 reference

7 August 2017

Martina E Spehlmann

4

1 reference

7 August 2017

Steve Shenouda

5

1 reference

7 August 2017

Ildelfonso Vicente-Suarez

7

1 reference

7 August 2017

Lars Eckmann

8

1 reference

7 August 2017

Martin F Kagnoff

9

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7 August 2017

language of work or name

English

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publication date

8 August 2011

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Journal of Experimental Medicine

7 August 2017

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7 August 2017

208

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7 August 2017

1889-1900

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7 August 2017

9

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IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ

7 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

The nuclear factor NF-kappaB pathway in inflammation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Inflammatory bowel disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor-dependent cell proliferation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

The first decade of biologic TNF antagonists in clinical practice: lessons learned, unresolved issues and future directions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Regulation of tissue homeostasis by NF-kappaB signalling: implications for inflammatory diseases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

CXCR2-dependent mucosal neutrophil influx protects against colitis-associated diarrhea caused by an attaching/effacing lesion-forming bacterial pathogen.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Nuclear factor-kappa B in intestinal protection and destruction

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Targeting the NF-kappaB pathway in asthma and chronic obstructive pulmonary disease.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Utility of the Citrobacter rodentium infection model in laboratory mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Chromatin immunoprecipitation and microarray-based analysis of protein location

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

NF-kappa B activation as a pathological mechanism of septic shock and inflammation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Differential expression of phosphorylated NF-kappaB/RelA in normal and psoriatic epidermis and downregulation of NF-kappaB in response to treatment with etanercept

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Intestinal mucosal responses to microbial infection

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

IkappaB-kinasebeta-dependent NF-kappaB activation provides radioprotection to the intestinal epithelium

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

NF-kappaB regulation in the immune system

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Missing pieces in the NF-kappaB puzzle

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

NF-kappaB at the crossroads of life and death

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

The NF-kappa B activation pathway: a paradigm in information transfer from membrane to nucleus

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Mechanisms of epithelial barrier impairment in HIV infection

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

NF-kappaB: a key role in inflammatory diseases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Predictive value of nuclear factor kappaB activity and plasma cytokine levels in patients with sepsis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Role of NFkappaB in the mortality of sepsis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

IkappaBalpha deficiency results in a sustained NF-kappaB response and severe widespread dermatitis in mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Epithelial cell I kappa B-kinase beta has an important protective role in Clostridium difficile toxin A-induced mucosal injury

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Expression pattern of Wnt signaling components in the adult intestine.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

Inhibitor of nuclear factor kappaB kinase beta is a key regulator of synovial inflammation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3171091

TRIF Signaling Stimulates Translation of TNF- mRNA via Prolonged Activation of MK2

26 September 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20110242

TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNF in LPS-stimulated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20110242

Hereditary vascular dementia linked to notch 3 mutations. CADASIL in British families

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20110242

Cyclooxygenase-selective inhibition of prostanoid formation: transducing biochemical selectivity into clinical read-outs

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20110242

Epithelial NEMO links innate immunity to chronic intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20110242

Association of the NFKBIA gene polymorphisms with susceptibility to autoimmune and inflammatory diseases: a meta-analysis

21 January 2018

1 reference

12 December 2020

The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion

1 reference

12 December 2020

Nuclear factor-kappa B in rheumatoid synovium. Localization of p50 and p65

1 reference

12 December 2020

Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice

1 reference

12 December 2020

RWJ 67657, a potent, orally active inhibitor of p38 mitogen-activated protein kinase

1 reference

12 December 2020

Anti-CD3 induces bi-phasic apoptosis in murine intestinal epithelial cells: possible involvement of the Fas/Fas ligand system in different T cell compartments

1 reference

12 December 2020

Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20110242

1 reference

7 August 2017

1 reference

7 August 2017

1 reference