A review and assessment of potential sources of ethnic differences in drug responsiveness (Q35217493)

7 August 2017

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title

A review and assessment of potential sources of ethnic differences in drug responsiveness (English)

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7 August 2017

Thorir D Bjornsson

1

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7 August 2017

John A Wagner

2

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7 August 2017

Stephen R Donahue

3

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7 August 2017

Dawn Harper

4

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7 August 2017

Aziz Karim

5

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7 August 2017

Marlene S Khouri

6

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7 August 2017

William R Murphy

7

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7 August 2017

Kristin Roman

8

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7 August 2017

Dennis Schneck

9

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7 August 2017

Daryl S Sonnichsen

10

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7 August 2017

Dennis J Stalker

11

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7 August 2017

Stephen D Wise

12

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7 August 2017

Stuart Dombey

13

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7 August 2017

Caroline Loew

14

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7 August 2017

1 September 2003

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The Journal of Clinical Pharmacology

7 August 2017

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7 August 2017

43

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7 August 2017

9

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7 August 2017

943-967

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Ethnic differences in drug disposition and responsiveness

7 August 2017

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https://api.crossref.org/works/10.1177%2F0091270003256065

Molecular basis of ethnic differences in drug disposition and response

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270003256065

Differences in plasma binding of drugs between Caucasians and Chinese subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Racial differences in propranolol enantiomer kinetics following simultaneous i.v. and oral administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Biochemistry and molecular biology of the human CYP2C subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Cytochrome P4502C9: an enzyme of major importance in human drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Allelic variants of human cytochrome P450 2C9: baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity, and prochiral selectivity of the wild-type and I359L mutant forms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Frequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Pharmacokinetics of chlorpheniramine, phenytoin, glipizide and nifedipine in an individual homozygous for the CYP2C9*3 allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Genetic polymorphism of cytochrome P450s, CYP2C19, and CYP2C9 in a Japanese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Incidence of S-mephenytoin hydroxylation deficiency in a Korean population and the interphenotypic differences in diazepam pharmacokinetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Molecular mechanisms of genetic polymorphisms of drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Genetic polymorphism of drug metabolising enzymes in African populations: implications for the use of neuroleptics and antidepressants

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Frequent occurrence of CYP2D6 gene duplication in Saudi Arabians

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Cytochrome P-450 3A4: regulation and role in drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

In vitro and in vivo drug interactions involving human CYP3A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Biotransformation of caffeine and theophylline in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Polymorphisms of CYP2A6 and its practical consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

The significance of the homozygous CYP2A6 deletion on nicotine metabolism: a new genotyping method of CYP2A6 using a single PCR-RFLP

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Deficient cotinine formation from nicotine is attributed to the whole deletion of the CYP2A6 gene in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Role of polymorphic and monomorphic human arylamine N-acetyltransferases in determining sulfamethoxazole metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Disease and Acetylation Polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Effect of acetylator phenotype on the rate at which procainamide induces antinuclear antibodies and the lupus syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Predominance of slow acetylators of N-acetyltransferase in a Hmong population residing in the United States.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Clinical pharmacokinetics and pharmacodynamics of celecoxib: a selective cyclo-oxygenase-2 inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Celecoxib: a new option in the treatment of arthropathies and familial adenomatous polyposis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Inter-subject and ethnic differences in paracetamol metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Interindividual and interethnic differences in the demethylation and glucuronidation of codeine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

A comparison of the pharmacokinetics of codeine and its metabolites in healthy Chinese and Caucasian extensive hydroxylators of debrisoquine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Biotransformation of pethidine: a comparative study of 24 h urine in three ethnic groups.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Pharmacogenetics and psychopharmacotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Ethnicity, culture, and neuropsychiatry

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Asian/non-Asian transcultural tricyclic antidepressant psychopharmacology: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Desipramine pharmacokinetics in Chinese and Caucasian volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

The impact of the CYP2D6 and CYP2C19 genotypes on venlafaxine pharmacokinetics in a Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Ethnic differences in the neuroleptic treatment of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

An investigation of ethnic and gender differences in the pharmacodynamics of haloperidol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Haloperidol and reduced haloperidol plasma levels in Chinese vs. non-Chinese psychiatric patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Differences in diazepam pharmacokinetics in Chinese and white Caucasians--relation to body lipid stores.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Diazepam effects and kinetics in Caucasians and Orientals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Diazepam metabolism in native Chinese poor and extensive hydroxylators of S-mephenytoin: interethnic differences in comparison with white subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

CYP3A activity in European American and Japanese men using midazolam as an in vivo probe

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Phenytoin disposition and toxicity: role of pharmacogenetic and interethnic factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Why are diazepam metabolism and polymorphic S-mephenytoin hydroxylation associated with each other in white and Korean populations but not in Chinese populations?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Phenytoin: pharmacogenetic polymorphism of 4'-hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Population pharmacokinetics of carbamazepine in Singapore epileptic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Racial differences in propranolol pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Influence of race or ethnicity on pharmacokinetics of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Steady state relative bioavailability and pharmacokinetics of oral propranolol in black and white North Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Use of beta-adrenergic receptor blockers in blacks

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Racial differences in drug response: isoproterenol effects before and after propranolol

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Hypertension: possible differential risk for blacks in Beta-Blocker Heart Attack Trial (BHAT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Racial differences in drug response. Altered sensitivity to and clearance of propranolol in men of Chinese descent as compared with American whites

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Attenuation of isoproterenol-mediated vasodilatation in blacks

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Vasodilation in black Americans: attenuated nitric oxide-mediated responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Nitroglycerin absorption from transdermal systems: formulation effects and metabolite concentrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Race and sex influence clearance of nifedipine: results of a population study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Factors affecting the absolute bioavailability of nifedipine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Ethnic differences in the pharmacokinetics of oral nifedipine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Does Chinese ethnicity affect the pharmacokinetics and pharmacodynamics of angiotensin-converting enzyme inhibitors?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Fosinopril: pharmacokinetics and pharmacodynamics in Chinese subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Comparison of the pharmacokinetics and pharmacodynamics of oral doses of perindopril in normotensive Chinese and Caucasian volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Factors determining the maintenance dose of warfarin in Chinese patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Racial background is a determinant of average warfarin dose required to maintain the INR between 2.0 and 3.0.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Heparin therapy in the Chinese--lower doses are required.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Pharmacodynamic effects of dopamine stratified by race

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Stereoselective steady state disposition and action of propafenone in Chinese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Racial background and lidocaine pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Pharmacokinetics of tolbutamide in ethnic Chinese

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Pharmacokinetics and pharmacodynamics of gliclazide in Caucasians and Australian Aborigines with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Insulin sensitivity differs among ethnic groups with a compensatory response in beta-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Body fat distribution and insulin resistance in healthy Asian Indians and Caucasians

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Plasma levels and pharmacokinetics of ethynyl estrogens in various populations. I. Ethynylestradiol

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Pharmacokinetics of ethinyl estradiol and mestranol

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Chromatographic patterns of urinary ethynyl estrogen metabolites in various populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Pharmacology of contraceptive steroids: a brief review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Inter-ethnic comparisons of the pharmacokinetics of the HMG-CoA reductase inhibitor cerivastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Pharmacokinetics of bambuterol during oral administration to asthmatic children

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Theophylline disposition in Korean patients with congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Gender-dependent racial difference in disposition of cyclosporine among healthy African American and white volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Neoral pharmacokinetics in Latino and Caucasian pediatric renal transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Cyclosporine bioavailability of Neoral and Sandimmune in white and black de novo renal transplant recipients. Neoral Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

The pharmacokinetics and metabolic disposition of tacrolimus: a comparison across ethnic groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Allelotype frequency of the thiopurine methyltransferase (TPMT) gene in Japanese

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Ethnic and genetic determinants of omeprazole disposition and effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Comparison of aminoglycoside pharmacokinetics in Asian, Hispanic, and Caucasian patients by using population pharmacokinetic methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Aminoglycoside pharmacokinetics in African-Americans with normal renal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Effect of ethnic origin on ampicillin bioavailability in healthy Sudanese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

The disposition of chloroquine in healthy Nigerians after single intravenous and oral doses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Pharmacokinetics of primaquine in man. II. Comparison of acute vs chronic dosage in Thai subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Race-linked differences in serum concentrations of dapsone, monoacetyldapsone and pyrimethamine during malaria prophylaxis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Ethnic differences in gastric sigma-alcohol dehydrogenase activity and ethanol first-pass metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Variation in ethanol pharmacokinetics and perceived gender and ethnic differences in alcohol elimination

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Drug, meal and formulation interactions influencing drug absorption after oral administration. Clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Role of tobacco smoking in pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Culture and psychopharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Pharmacodynamics and pharmacokinetics of intravenous glibenclamide in Caucasian and Chinese patients with type-2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

Triazolam pharmacokinetics and pharmacodynamics in Caucasians and Southern Asians: ethnicity and CYP3A activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256065

21 January 2018

Identifiers

DOI

10.1177/0091270003256065

1 reference

7 August 2017

1 reference