Forced dimerization increases the activity of ΔEGFR/EGFRvIII and enhances its oncogenicity (Q35218835)

7 August 2017

title

Forced dimerization increases the activity of ΔEGFR/EGFRvIII and enhances its oncogenicity (English)

1 reference

7 August 2017

Oliver Bogler

4

0 references

author name string

Yeohyeon Hwang

series ordinal

1

1 reference

7 August 2017

Vaibhav Chumbalkar

series ordinal

2

1 reference

7 August 2017

Khatri Latha

series ordinal

3

1 reference

7 August 2017

publication date

20 July 2011

1 reference

Molecular Cancer Research

7 August 2017

published in

1 reference

7 August 2017

volume

9

1 reference

7 August 2017

issue

9

1 reference

7 August 2017

page(s)

1199-1208

1 reference

Glioma Specific Extracellular Missense Mutations in the First Cysteine Rich Region of Epidermal Growth Factor Receptor (EGFR) Initiate Ligand Independent Activation

7 August 2017

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13 July 2018

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13 July 2018

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Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma

13 July 2018

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Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma

13 July 2018

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Requirement of Tyr-992 and Tyr-1173 in phosphorylation of the epidermal growth factor receptor by ionizing radiation and modulation by SHP2.

13 July 2018

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Alix/AIP1 antagonizes epidermal growth factor receptor downregulation by the Cbl-SETA/CIN85 complex.

13 July 2018

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Role of the Grb2-associated binder 1/SHP-2 interaction in cell growth and transformation

13 July 2018

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13 July 2018

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Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization

13 July 2018

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Ligand-induced, receptor-mediated dimerization and activation of EGF receptor

13 July 2018

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Epidermal growth factor receptor vIII enhances tumorigenicity in human breast cancer

13 July 2018

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Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers

13 July 2018

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A G-CSF receptor-gyrase B fusion gene: A new type of molecular switch for expansion of genetically modified hematopoietic cells

13 July 2018

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Activation and functional analysis of Janus kinase 2 in BA/F3 cells using the coumermycin/gyrase B system

13 July 2018

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Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificity

13 July 2018

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Small-molecule control of insulin and PDGF receptor signaling and the role of membrane attachment

13 July 2018

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Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor

13 July 2018

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Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII)

13 July 2018

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The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling

13 July 2018

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A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis

13 July 2018

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Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway

13 July 2018

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Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization.

13 July 2018

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Transformational and altered signal transduction by a naturally occurring mutant EGF receptor

13 July 2018

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A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

13 July 2018

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Controlling Signal Transduction with Synthetic Ligands

13 July 2018

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Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification

13 July 2018

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Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

13 July 2018

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Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails

13 July 2018

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Quantitative comparison of IMAC and TiO2 surfaces used in the study of regulated, dynamic protein phosphorylation

13 July 2018

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Prognostic effect of epidermal growth factor receptor and EGFRvIII in glioblastoma multiforme patients.

26 September 2018

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Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion

26 September 2018

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26 September 2018

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12 December 2020

Signal transduction and growth control in normal and cancer cells

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12 December 2020

Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors

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12 December 2020

Epidermal growth factor receptor and Ink4a/Arf

1 reference

12 December 2020

10.1158/1541-7786.MCR-11-0229

Identifiers

DOI

1 reference

release_ciswv6oy4jcctmj4cqegfjuk6e

7 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ciswv6oy4jcctmj4cqegfjuk6e

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3175255

1 reference

7 August 2017

1 reference