Connective tissue growth factor modulates adult β-cell maturity and proliferation to promote β-cell regeneration in mice (Q35220576)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392241%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

Connective tissue growth factor modulates adult β-cell maturity and proliferation to promote β-cell regeneration in mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392241%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

2

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22 February 2020

Jennifer Peek

4

1 reference

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22 February 2020

Pedro Luis Herrera

7

1 reference

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22 February 2020

author name string

Kimberly G Riley

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392241%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Matthew F Maulis

3

1 reference

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22 February 2020

Fabrizio Thorel

5

1 reference

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22 February 2020

David R Brigstock

6

1 reference

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22 February 2020

Maureen Gannon

8

1 reference

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22 February 2020

language of work or name

English

0 references

publication date

12 November 2014

1 reference

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22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392241%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

64

1 reference

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22 February 2020

issue

4

1 reference

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22 February 2020

page(s)

1284-1298

1 reference

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describes a project that uses

22 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4375083/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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BMP9 inhibits the bone metastasis of breast cancer cells by downregulating CCN2 (connective tissue growth factor, CTGF) expression

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Regulation of pancreatic function by connective tissue growth factor (CTGF, CCN2)

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Inactivation of the dual Bmp/Wnt inhibitor Sostdc1 enhances pancreatic islet function

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Pancreatic beta cells in very old mice retain capacity for compensatory proliferation

13 July 2018

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Differential regulation of embryonic and adult β cell replication

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PDGF signalling controls age-dependent proliferation in pancreatic β-cells

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Connective tissue growth factor acts within both endothelial cells and beta cells to promote proliferation of developing beta cells

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MafA and MafB regulate genes critical to beta-cells in a unique temporal manner

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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Connective-tissue growth factor modulates WNT signalling and interacts with the WNT receptor complex

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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26 September 2018

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Growth and regeneration of adult beta cells does not involve specialized progenitors.

26 September 2018

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Transforming growth factor-beta receptor type I-dependent fibrogenic gene program is mediated via activation of Smad1 and ERK1/2 pathways.

26 September 2018

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Lineage tracing evidence for in vitro dedifferentiation but rare proliferation of mouse pancreatic beta-cells.

26 September 2018

1 reference

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Connective tissue growth factor (CTGF/CCN2) is a downstream mediator for TGF-beta1-induced extracellular matrix production in osteoblasts.

26 September 2018

1 reference

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The FoxM1 transcription factor is required to maintain pancreatic beta-cell mass.

26 September 2018

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Very slow turnover of beta-cells in aged adult mice

26 September 2018

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TGF-beta1-induced connective tissue growth factor (CCN2) expression in human renal proximal tubule epithelial cells requires Ras/MEK/ERK and Smad signalling.

26 September 2018

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26 September 2018

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Connective tissue growth factor is a regulator for fibrosis in human chronic pancreatitis

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25392241

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2337/DB14-1195

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392241%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392241%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference