Regulation of pancreatic function by connective tissue growth factor (CTGF, CCN2) (Q27012580)

Crossref

David R. Brigstock

series ordinal

2

1 reference

Crossref

language of work or name

1 reference

February 2013

1 reference

Cytokine and Growth Factor Reviews

published in

1 reference

volume

24

1 reference

issue

1

1 reference

page(s)

59-68

1 reference

Connective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesis

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Functions and mechanisms of action of CCN matricellular proteins

21 March 2017

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The matricellular protein CCN1 is essential for cardiac development

21 March 2017

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Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development

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Proposal for a unified CCN nomenclature

21 March 2017

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CYR61 (CCN1) is essential for placental development and vascular integrity

21 March 2017

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neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

21 March 2017

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Gene expression profiling of a mouse model of pancreatic islet dysmorphogenesis

21 March 2017

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Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets

21 March 2017

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Connective tissue growth factor CCN2 interacts with and activates the tyrosine kinase receptor TrkA

21 March 2017

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Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development

21 March 2017

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Connective tissue growth factor is involved in pancreatic repair and tissue remodeling in human and rat acute necrotizing pancreatitis

21 March 2017

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Pulmonary hypoplasia in the connective tissue growth factor (Ctgf) null mouse

21 March 2017

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TGF-beta signaling and the fibrotic response

21 March 2017

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Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

7 April 2017

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Differential regulation of embryonic and adult β cell replication

7 April 2017

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Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma

28 September 2017

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Connective tissue growth factor acts within both endothelial cells and beta cells to promote proliferation of developing beta cells

28 September 2017

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CCN1/CYR61: the very model of a modern matricellular protein.

28 September 2017

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The fibrosis of chronic pancreatitis: new insights into the role of pancreatic stellate cells

28 September 2017

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Pancreas organogenesis: from bud to plexus to gland

28 September 2017

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The CCN family: a new class of inflammation modulators?

28 September 2017

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Transcript profiling identifies novel key players mediating the growth inhibitory effect of NS-398 on human pancreatic cancer cells.

28 September 2017

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The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF.

28 September 2017

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28 September 2017

Islet cell development.

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The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth

28 September 2017

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Identification of phylogenetically conserved enhancer elements implicated in pancreas development in the WISP1 and CTGF orthologs

28 September 2017

1 reference

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Analysis of CCN2 promoter activity in PANC-1 cells: regulation by ras/MEK/ERK

28 September 2017

1 reference

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Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) gene

28 September 2017

1 reference

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Pancreatic cancer-associated stroma production

28 September 2017

1 reference

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Transforming growth factor-beta and fibrosis

28 September 2017

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Inhibitory effects of interferon-gamma on activation of rat pancreatic stellate cells are mediated by STAT1 and involve down-regulation of CTGF expression

28 September 2017

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Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression

28 September 2017

1 reference

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A novel integrin alpha5beta1 binding domain in module 4 of connective tissue growth factor (CCN2/CTGF) promotes adhesion and migration of activated pancreatic stellate cells

28 September 2017

1 reference

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Structural and functional properties of CCN proteins

28 September 2017

1 reference

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The role of connective tissue growth factor, a multifunctional matricellular protein, in fibroblast biology

28 September 2017

1 reference

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Signaling and transcriptional control of pancreatic organogenesis

28 September 2017

1 reference

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Exploring the host desmoplastic response to pancreatic carcinoma: gene expression of stromal and neoplastic cells at the site of primary invasion

28 September 2017

1 reference

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Invasion-specific genes in malignancy: serial analysis of gene expression comparisons of primary and passaged cancers.

28 September 2017

1 reference

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Activation of pancreatic stellate cells in human and experimental pancreatic fibrosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508350

Mutations in the CCN gene family member WISP3 cause progressive pseudorheumatoid dysplasia.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508350

The connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed (CCN) family

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3508350

The CCN family of angiogenic regulators: the integrin connection

28 September 2017

1 reference

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Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture.

28 September 2017

1 reference

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Increased expression of transforming growth factor beta s after acute oedematous pancreatitis in rats suggests a role in pancreatic repair

28 September 2017

1 reference

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Tumor-suppressive pathways in pancreatic carcinoma.

28 September 2017

1 reference

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Progression of alcoholic acute to chronic pancreatitis

28 September 2017

1 reference

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The modular architecture of a new family of growth regulators related to connective tissue growth factor

28 September 2017

1 reference

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Accumulation of extracellular matrix and developmental dysregulation in the pancreas by transgenic production of transforming growth factor-beta 1.

28 September 2017

1 reference

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NOV/CCN3 upregulates CCL2 and CXCL1 expression in astrocytes through beta1 and beta5 integrins

28 September 2017

1 reference

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Connective tissue growth factor production by activated pancreatic stellate cells in mouse alcoholic chronic pancreatitis

31 May 2018

1 reference

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Expression of connective tissue growth factor in pancreatic cancer cell lines

31 May 2018

1 reference

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Desmoplastic reaction influences pancreatic cancer growth behavior

31 May 2018

1 reference

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K-ras mutations in pancreatic ductal proliferative lesions

31 May 2018

1 reference

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Ethanol-mediated expression of connective tissue growth factor (CCN2) in mouse pancreatic stellate cells

31 May 2018

1 reference

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Molecular insights into connective tissue growth factor action in rat pancreatic stellate cells

28 November 2018

1 reference

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High glucose increases extracellular matrix production in pancreatic stellate cells by activating the renin-angiotensin system

28 November 2018

1 reference

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Connective tissue growth factor (CCN2) in rat pancreatic stellate cell function: integrin alpha5beta1 as a novel CCN2 receptor

28 November 2018

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Low density lipoprotein receptor-related protein (LRP) is a heparin-dependent adhesion receptor for connective tissue growth factor (CTGF) in rat activated hepatic stellate cells

28 November 2018

1 reference

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Selective β-Cell Loss and α-Cell Expansion in Patients with Type 2 Diabetes Mellitus in Korea

28 November 2018

1 reference

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Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis

28 November 2018

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12 December 2020

Hyperglycemia and hyperinsulinemia have additive effects on activation and proliferation of pancreatic stellate cells: possible explanation of islet-specific fibrosis in type 2 diabetes mellitus

1 reference

12 December 2020

Immunohistochemical localization of connective tissue growth factor (CTGF) in the mouse embryo between days 7.5 and 14.5 of gestation

1 reference

12 December 2020

The influence of transforming growth factor beta 1 on the expression of genes coding for matrix metalloproteinases and tissue inhibitors of metalloproteinases during regeneration from cerulein-induced pancreatitis

1 reference

12 December 2020

Extracellular matrix is reduced by inhibition of transforming growth factor beta1 in pancreatitis in the rat

1 reference

12 December 2020

Expression and differential regulation of connective tissue growth factor in pancreatic cancer cells

1 reference

12 December 2020

Connective tissue growth factor-specific antibody attenuates tumor growth, metastasis, and angiogenesis in an orthotopic mouse model of pancreatic cancer

1 reference

12 December 2020

Effects of fibrogenic mediators on the development of pancreatic fibrosis in a TGF-beta1 transgenic mouse model

1 reference

12 December 2020

Establishment of a novel collagenase perfusion method to isolate rat pancreatic stellate cells and investigation of their gene expression of TGF-beta1, type I collagen, and CTGF in primary culture or freshly isolated cells

1 reference

12 December 2020

Transforming growth factor beta promotes development of fibrosis after repeated courses of acute pancreatitis in mice

1 reference

12 December 2020

Comparison of epidermal growth factor and transforming growth factor-beta1 expression in hormone-induced acute pancreatitis in rats

1 reference

12 December 2020

Connective tissue growth factor is a regulator for fibrosis in human chronic pancreatitis

1 reference

12 December 2020

Enhanced expression of TGF-betas and their receptors in human acute pancreatitis

1 reference

12 December 2020

Stromal SPARC expression and patient survival after chemoradiation for non-resectable pancreatic adenocarcinoma

1 reference

12 December 2020

10.1016/J.CYTOGFR.2012.07.001

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24 November 2022