Phosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury (Q35225599)

7 August 2017

title

Phosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury (English)

1 reference

7 August 2017

John Doukas

1

1 reference

7 August 2017

Wolfgang Wrasidlo

2

1 reference

7 August 2017

Glenn Noronha

3

1 reference

7 August 2017

Elena Dneprovskaia

4

1 reference

7 August 2017

Richard Fine

5

1 reference

7 August 2017

Sara Weis

6

1 reference

7 August 2017

John Hood

7

1 reference

7 August 2017

Anthony Demaria

8

1 reference

7 August 2017

Richard Soll

9

1 reference

7 August 2017

David Cheresh

10

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7 August 2017

language of work or name

English

0 references

publication date

15 December 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

7 August 2017

published in

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7 August 2017

volume

103

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7 August 2017

issue

52

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7 August 2017

page(s)

19866-19871

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The survival kinases Akt and Pim as potential pharmacological targets

7 August 2017

cites work

1 reference

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PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury

27 July 2018

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27 July 2018

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The mitochondrial death pathway and cardiac myocyte apoptosis

27 July 2018

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Essential role for the p110delta phosphoinositide 3-kinase in the allergic response

27 July 2018

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Myocardial protection at a crossroads: the need for translation into clinical therapy

27 July 2018

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Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction

27 July 2018

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New directions for protecting the heart against ischaemia-reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway

27 July 2018

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Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Early expression of angiogenesis factors in acute myocardial ischemia and infarction

27 July 2018

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Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells

27 July 2018

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Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart.

27 July 2018

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Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

27 July 2018

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27 July 2018

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Specific binding of vascular permeability factor to endothelial cells.

27 July 2018

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Ischemia reperfusion injury and histamine release in isolated and perfused guinea-pig heart: Pharmacological interventions

27 July 2018

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Intracoronary C5a induces myocardial ischemia by mechanisms independent of the neutrophil: leukocyte filters desensitize the myocardium to C5a.

27 July 2018

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Sephadex induced inflammation in rats (author's transl)

27 July 2018

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Leukotrienes D4 and E4 produced in myocardium impair coronary flow and ventricular function after two hours of global ischaemia in rat heart.

27 July 2018

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Inhibition of the tissue factor-thrombin pathway limits infarct size after myocardial ischemia-reperfusion injury by reducing inflammation

21 January 2018

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Phosphoinositide 3-kinase gamma is an essential amplifier of mast cell function

21 January 2018

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Involvement of phosphoinositide 3-kinases in neutrophil activation and the development of acute lung injury

21 January 2018

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Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-Akt pathway

21 January 2018

1 reference

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G protein-coupled receptor internalization signaling is required for cardioprotection in ischemic preconditioning

21 January 2018

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Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling

21 January 2018

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Opioid-induced cardioprotection occurs via glycogen synthase kinase beta inhibition during reperfusion in intact rat hearts

21 January 2018

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Ischemic preconditioning activates phosphatidylinositol-3-kinase upstream of protein kinase C

21 January 2018

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Phosphoinositide 3-kinase gamma-deficient hearts are protected from the PAF-dependent depression of cardiac contractility

21 January 2018

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Extraction of well-fitting substructures: root-mean-square deviation and the difference distance matrix

21 January 2018

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Resistance to thromboembolism in PI3Kgamma-deficient mice.

21 January 2018

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Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.

21 January 2018

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PI3Kgamma inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus

26 September 2018

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Phosphatidylinositol-3-kinase signaling is required for erythropoietin-mediated acute protection against myocardial ischemia/reperfusion injury

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1702529

Adrenomedullin infusion attenuates myocardial ischemia/reperfusion injury through the phosphatidylinositol 3-kinase/Akt-dependent pathway

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1702529

Vascular Endothelial Growth Factor Induction of the Angiogenic Phenotype Requires Ras Activation

26 September 2018

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Thromboxane and prostacyclin release from ischaemic myocardium in relation to arrhythmias

21 January 2018

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Human endothelial cells are target for platelet-activating factor. I. Platelet-activating factor induces changes in cytoskeleton structures

21 January 2018

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Wortmannin, a potent antineutrophil agent, exerts cardioprotective effects in myocardial ischemia/reperfusion

15 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17172449

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Production and Biologic Interactions of Prostacyclin and Platelet-Activating Factor in Acute Myocardial Ischemia in the Perfused Rabbit Heart

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17172449

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Hypoxia induces endothelial cells to increase their adherence for neutrophils: role of PAF

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17172449

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0606956103

1 reference

7 August 2017

0 references

1 reference

7 August 2017

1 reference