The conserved protein EF4 (LepA) modulates the elongation cycle of protein synthesis (Q35239754)

7 August 2017

title

The conserved protein EF4 (LepA) modulates the elongation cycle of protein synthesis (English)

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7 August 2017

1

Hanqing Liu

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7 August 2017

Chunlai Chen

2

1 reference

7 August 2017

Haibo Zhang

3

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7 August 2017

Jaskiran Kaur

4

1 reference

7 August 2017

Yale E Goldman

5

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7 August 2017

Barry S Cooperman

6

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7 August 2017

language of work or name

English

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publication date

19 September 2011

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7 August 2017

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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7 August 2017

volume

108

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7 August 2017

issue

39

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7 August 2017

page(s)

16223-16228

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Single-molecule fluorescence measurements of ribosomal translocation dynamics.

7 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

Elongation factor 4 (EF4/LepA) accelerates protein synthesis at increased Mg2+ concentrations

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

Structure and dynamics of a processive Brownian motor: the translating ribosome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

Interrupted catalysis: the EF4 (LepA) effect on back-translocation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

Translation factor LepA contributes to tellurite resistance in Escherichia coli but plays no apparent role in the fidelity of protein synthesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

What recent ribosome structures have revealed about the mechanism of translation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

Synthesis and functional activity of tRNAs labeled with fluorescent hydrazides in the D-loop

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

The structure of LepA, the ribosomal back translocase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

Kinetically competent intermediates in the translocation step of protein synthesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

A "silent" polymorphism in the MDR1 gene changes substrate specificity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

The highly conserved LepA is a ribosomal elongation factor that back-translocates the ribosome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

The cryo-EM structure of a translation initiation complex from Escherichia coli

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

tRNA dynamics on the ribosome during translation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

EF-G-independent reactivity of a pre-translocation-state ribosome complex with the aminoacyl tRNA substrate puromycin supports an intermediate (hybrid) state of tRNA binding

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

Translation is a non-uniform process. Effect of tRNA availability on the rate of elongation of nascent polypeptide chains

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

lep operon proximal gene is not required for growth or secretion by Escherichia coli

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

The efficiency of folding of some proteins is increased by controlled rates of translation in vivo. A hypothesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

Transient ribosomal attenuation coordinates protein synthesis and co-translational folding.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

Spontaneous reverse movement of mRNA-bound tRNA through the ribosome.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

Reverse translocation of tRNA in the ribosome.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

Conformational changes of the small ribosomal subunit during elongation factor G-dependent tRNA-mRNA translocation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

An elongation factor G-induced ribosome rearrangement precedes tRNA-mRNA translocation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

Rapid kinetic analysis of EF-G-dependent mRNA translocation in the ribosome

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182707

Deletion of the elongation factor 4 gene (lepA) in Streptomyces coelicolor enhances the production of the calcium-dependent antibiotic

26 September 2018

1 reference

12 December 2020

Distribution of rare triplets along mRNA and their relation to protein folding

1 reference

12 December 2020

Synonymous codon substitutions affect ribosome traffic and protein folding during in vitro translation

1 reference

12 December 2020

Regulation of the in vivo synthesis of the polypeptide chain elongation factors in Escherichia coli

1 reference

12 December 2020

Puromycin reaction of the A-site bound peptidyl-tRNA

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1103820108

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7 August 2017

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7 August 2017

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