Dysregulated Sonic hedgehog signaling and medulloblastoma consequent to IFN-alpha-stimulated STAT2-independent production of IFN-gamma in the brain (Q35243016)

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English	Dysregulated Sonic hedgehog signaling and medulloblastoma consequent to IFN-alpha-stimulated STAT2-independent production of IFN-gamma in the brain	scientific article

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scholarly article

1 reference

Europe PubMed Central

7 August 2017

Dysregulated Sonic hedgehog signaling and medulloblastoma consequent to IFN-alpha-stimulated STAT2-independent production of IFN-gamma in the brain (English)

1 reference

Europe PubMed Central

7 August 2017

medulloblastoma

0 references

author name string

Jianping Wang

1

1 reference

Europe PubMed Central

7 August 2017

Ngan Pham-Mitchell

2

1 reference

Europe PubMed Central

7 August 2017

Christian Schindler

3

1 reference

Europe PubMed Central

7 August 2017

Iain L Campbell

4

1 reference

Europe PubMed Central

7 August 2017

language of work or name

0 references

publication date

1 August 2003

1 reference

Europe PubMed Central

7 August 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

7 August 2017

112

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Europe PubMed Central

7 August 2017

4

1 reference

Europe PubMed Central

7 August 2017

535-543

1 reference

Europe PubMed Central

7 August 2017

Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

STAT1 deficiency unexpectedly and markedly exacerbates the pathophysiological actions of IFN-alpha in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-alpha-inducible genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

STAT2 acts as a host range determinant for species-specific paramyxovirus interferon antagonism and simian virus 5 replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Gli and hedgehog in cancer: tumours, embryos and stem cells.

1 reference

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27 July 2018

Stat proteins and oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Constitutive activation of Stat3alpha in brain tumors: localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

The WHO classification of tumors of the nervous system

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27 July 2018

Expression of human neurotropic polyomavirus JCV late gene product agnoprotein in human medulloblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Regulation of signal transducer and activator of transcription and suppressor of cytokine-signaling gene expression in the brain of mice with astrocyte-targeted production of interleukin-12 or experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Medulloblastoma: clinical and biologic aspects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Biologic consequences of Stat1-independent IFN signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

The developmental biology of brain tumors.

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27 July 2018

Mumps virus can suppress the effective augmentation of HPC-induced apoptosis by IFN-gamma through disruption of IFN signaling in U937 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Cytokines and STAT signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Catalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Structural and functional neuropathology in transgenic mice with CNS expression of IFN-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Sonic hedgehog regulates the growth and patterning of the cerebellum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

How cells respond to interferons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Interferon-alpha activates signal transducers and activators of transcription 5 and 6 in Daudi cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

STAT3 complements defects in an interferon-resistant cell line: evidence for an essential role for STAT3 in interferon signaling and biological activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Proteolytic processing yields two secreted forms of sonic hedgehog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Interferon-induced antiviral actions and their regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Intrathecal synthesis of interferon-alpha in infants with progressive familial encephalopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Medulloblastoma: tumor biological and clinical perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

Interferon-alpha in lupus psychosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

27 July 2018

An autoradiographic analysis of histogenesis in the mouse cerebellum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

26 September 2018

Induction of medulloblastomas in mice by sonic hedgehog, independent of Gli1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

26 September 2018

Polyomavirus and medulloblastoma: a smoking gun or guilt by association?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

26 September 2018

Regional hypomyelination and dysplasia in transgenic mice with astrocyte-directed expression of interferon-gamma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

26 September 2018

Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

26 September 2018

Viral inhibition of interferon signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

26 September 2018

Gli genes in development and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

26 September 2018

Interferons as a paradigm for cytokine signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

26 September 2018

Chemokines and the inflammatory response to viral infection in the central nervous system with a focus on lymphocytic choriomeningitis virus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

26 September 2018

Negative regulation of the JAK/STAT pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

26 September 2018

The role of Stat4 in species-specific regulation of Th cell development by type I IFNs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

26 September 2018

Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

26 September 2018

Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

26 September 2018

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171394

26 September 2018

Roles of IFN-gamma and IFN-alpha in IL-12-induced T helper cell-1 development

1 reference

https://pubmed.ncbi.nlm.nih.gov/12925694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neglected role of type I interferon in the T-cell response: implications for its clinical use

1 reference

https://pubmed.ncbi.nlm.nih.gov/12925694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted CNS expression of interferon-gamma in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar development

1 reference

https://pubmed.ncbi.nlm.nih.gov/12925694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measuring HIV-1 RNA and interferon-alpha in the cerebrospinal fluid of AIDS patients: insights into the pathogenesis of AIDS Dementia Complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/12925694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/12925694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune response in Stat2 knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12925694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox

1 reference

https://pubmed.ncbi.nlm.nih.gov/12925694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI200318637

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

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