Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members (Q35250965)

7 August 2017

title

Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members (English)

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heparan sulfate proteoglycans

7 August 2017

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5

André Bensadoun

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7 August 2017

6

Joseph L Witztum

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7 August 2017

Jennifer M MacArthur

1

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7 August 2017

Joseph R Bishop

2

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7 August 2017

Kristin I Stanford

3

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7 August 2017

Lianchun Wang

4

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7 August 2017

Jeffrey D Esko

7

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7 August 2017

language of work or name

English

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publication date

1 January 2007

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Journal of Clinical Investigation

7 August 2017

published in

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7 August 2017

volume

117

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7 August 2017

issue

1

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7 August 2017

page(s)

153-164

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Isolation and characterization of low sulfated heparan sulfate sequences with affinity for lipoprotein lipase

7 August 2017

cites work

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27 July 2018

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27 July 2018

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Perlecan heparan sulfate proteoglycan: a novel receptor that mediates a distinct pathway for ligand catabolism

27 July 2018

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Binding of hepatic lipase to heparin. Identification of specific heparin-binding residues in two distinct positive charge clusters

27 July 2018

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27 July 2018

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27 July 2018

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Heparin is essential for the storage of specific granule proteases in mast cells

27 July 2018

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Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL

27 July 2018

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Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E

27 July 2018

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Chylomicron remnant uptake is regulated by the expression and function of heparan sulfate proteoglycan in hepatocytes

27 July 2018

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Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants

27 July 2018

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Heparan sulfate proteoglycans participate in hepatic lipaseand apolipoprotein E-mediated binding and uptake of plasma lipoproteins, including high density lipoproteins

27 July 2018

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Hepatic uptake of chylomicron remnants

27 July 2018

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Cell-surface heparan sulfate proteoglycans: dynamic molecules mediating ligand catabolism.

27 July 2018

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The syndecan family of proteoglycans. Novel receptors mediating internalization of atherogenic lipoproteins in vitro

27 July 2018

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Genetics and molecular biology of hepatic lipase

27 July 2018

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Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes

27 July 2018

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27 July 2018

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Variable heparan sulfate proteoglycan binding of apolipoprotein E variants may modulate the expression of type III hyperlipoproteinemia

27 July 2018

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Oligosaccharide sequences of endothelial cell surface heparan sulfate proteoglycan with affinity for lipoprotein lipase

27 July 2018

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Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4.

27 July 2018

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Role of heparan sulfate proteoglycans in the binding and uptake of apolipoprotein E-enriched remnant lipoproteins by cultured cells

27 July 2018

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Dominant expression of type III hyperlipoproteinemia. Pathophysiological insights derived from the structural and kinetic characteristics of ApoE-1 (Lys146-->Glu)

27 July 2018

1 reference

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Intracellular localization and metabolism of chylomicron remnants in the livers of low density lipoprotein receptor-deficient mice and apoE-deficient mice. Evidence for slow metabolism via an alternative apoE-dependent pathway

27 July 2018

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Hepatic uptake of chylomicron remnants in WHHL rabbits: a mechanism genetically distinct from the low density lipoprotein receptor

27 July 2018

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Apolipoprotein E localization in rat hepatocytes by immunogold labeling of cryothin sections

27 July 2018

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Chylomicron remnant clearance from the plasma is normal in familial hypercholesterolemic homozygotes with defined receptor defects

27 July 2018

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The unstirred water layer as a site of control of apolipoprotein B secretion

27 July 2018

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Identification and characterization of the endothelial cell surface lipoprotein lipase receptor

27 July 2018

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Endothelial heparan sulfate deficiency impairs L-selectin- and chemokine-mediated neutrophil trafficking during inflammatory responses

27 July 2018

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Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function

26 September 2018

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26 September 2018

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Hepatic catabolism of remnant lipoproteins: where the action is.

26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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Heparin-binding defective lipoprotein lipase is unstable and causes abnormalities in lipid delivery to tissues

26 September 2018

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Interaction of the N-terminal domain of apolipoprotein E4 with heparin

26 September 2018

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Sustained somatic gene inactivation by viral transfer of Cre recombinase.

26 September 2018

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Hepatic lipase is abundant on both hepatocyte and endothelial cell surfaces in the liver.

26 September 2018

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Enhanced binding and uptake of remnant lipoproteins by hepatic lipase-secreting hepatoma cells in culture.

26 September 2018

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Intravenous heparinase inhibits remnant lipoprotein clearance from the plasma and uptake by the liver: in vivo role of heparan sulfate proteoglycans

26 September 2018

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Heparin decreases the degradation rate of lipoprotein lipase in adipocytes

26 September 2018

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Lipoprotein lipase in liver. Release by heparin and immunocytochemical localization.

26 September 2018

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Two new monoclonal antibody-based enzyme-linked assays of apolipoprotein B

26 September 2018

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12 December 2020

Heparan sulfate proteoglycan-mediated uptake of apolipoprotein E-triglyceride-rich lipoprotein particles: a major pathway at physiological particle concentrations

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12 December 2020

Sensitive high-performance liquid chromatographic method with fluorometric detection for the determination of heparin and heparan sulfate in biological samples: application to human urinary heparan sulfate

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12 December 2020

A modified uronic acid carbazole reaction

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12 December 2020

Nitrocellulose Filter Binding to Assess Binding of Glycosaminoglycans to Proteins

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12 December 2020

Heparan sulfate structure in mice with genetically modified heparan sulfate production

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12 December 2020

Acetoacetylated lipoproteins used to distinguish fibroblasts from macrophages in vitro by fluorescence microscopy

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12 December 2020

Decreased activity of the heparan sulfate-modifying enzyme glucosaminyl N-deacetylase in hepatocytes from streptozotocin-diabetic rats

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12 December 2020

Glycosylphosphatidylinositol-anchored and core protein-intercalated heparan sulfate proteoglycans in rat ovarian granulosa cells have distinct secretory, endocytotic, and intracellular degradative pathways

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12 December 2020

Mechanisms by which lipoprotein lipase alters cellular metabolism of lipoprotein(a), low density lipoprotein, and nascent lipoproteins. Roles for low density lipoprotein receptors and heparan sulfate proteoglycans

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12 December 2020

Liver heparan sulfate structure. A novel molecular design

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12 December 2020

Lactoferrin binding to heparan sulfate proteoglycans and the LDL receptor-related protein. Further evidence supporting the importance of direct binding of remnant lipoproteins to HSPG

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12 December 2020

Mild dyslipidemia in mice following targeted inactivation of the hepatic lipase gene

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12 December 2020

Apolipoprotein E isoforms and rare mutations: parallel reduction in binding to cells and to heparin reflects severity of associated type III hyperlipoproteinemia

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12 December 2020

Differences in the mechanisms of uptake and endocytosis of small and large chylomicron remnants by rat liver

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12 December 2020

Role of the low density lipoprotein (LDL) receptor pathway in the metabolism of chylomicron remnants. A quantitative study in knockout mice lacking the LDL receptor, apolipoprotein E, or both

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12 December 2020

DNA excision in liver by an albumin-Cre transgene occurs progressively with age

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12 December 2020

Reduced Sulfation of Liver Heparan Sulfate in Experimentally Diabetic Rats

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12 December 2020

Enzyme-linked immunosorbent assay for rat hepatic triglyceride lipase

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12 December 2020

Density gradient ultracentrifugation of serum lipoproteins in a swinging bucket rotor

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12 December 2020

Isolation and characterization of apolipoprotein E

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12 December 2020

Preparation, characterization, and measurement of hepatic lipase

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12 December 2020

Identifiers

DOI

10.1172/JCI29154

1 reference

7 August 2017

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7 August 2017

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