Directed evolution of polymerase function by compartmentalized self-replication (Q35272411)

7 August 2017

Directed evolution of polymerase function by compartmentalized self-replication (English)

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7 August 2017

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Ghadessy FJ

1

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7 August 2017

Ong JL

series ordinal

2

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7 August 2017

Holliger P

series ordinal

3

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7 August 2017

language of work or name

English

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publication date

27 March 2001

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Proceedings of the National Academy of Sciences of the United States of America

7 August 2017

6

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based on heuristic

inferred from page(s)

published in

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7 August 2017

98

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7 August 2017

8

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7 August 2017

4552-4557

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Mutators and sex in bacteria: conflict between adaptive strategies

7 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

An open and closed case for all polymerases.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

DNA polymerases: structural diversity and common mechanisms

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Man-made cell-like compartments for molecular evolution.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Molecular evolution by staggered extension process (StEP) in vitro recombination

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

DNA shuffling of a family of genes from diverse species accelerates directed evolution

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Allele identification using immobilized mismatch binding protein: detection and identification of antibiotic-resistant bacteria and determination of sheep susceptibility to scrapie

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

RNA virus mutations and fitness for survival

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Evolution of high mutation rates in experimental populations of E. coli

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

The thioredoxin binding domain of bacteriophage T7 DNA polymerase confers processivity on Escherichia coli DNA polymerase I

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Thermostable DNA polymerases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Random mutagenesis of Thermus aquaticus DNA polymerase I: concordance of immutable sites in vivo with the crystal structure

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Structure of Taq polymerase with DNA at the polymerase active site

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

High-level expression, purification, and enzymatic characterization of full-length Thermus aquaticus DNA polymerase and a truncated form deficient in 5' to 3' exonuclease activity.

27 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

27 July 2018

https://api.crossref.org/works/10.1073%2FPNAS.071052198

Function and structure relationships in DNA polymerases

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Amplification and detection of lentiviral DNA inside cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Nucleoside diphosphate kinase from Myxococcus xanthus. I. Cloning and sequencing of the gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Purification of Thermus aquaticus DNA polymerase expressed in Escherichia coli.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Prevention of pre-PCR mis-priming and primer dimerization improves low-copy-number amplifications

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

The fidelity of Taq polymerase catalyzing PCR is improved by an N-terminal deletion.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

In-cell PCR from mRNA: amplifying and linking the rearranged immunoglobulin heavy and light chain V-genes within single cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

The concept of cellular evolution

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

The hypercycle. A principle of natural self-organization. Part A: Emergence of the hypercycle

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

A method for the selection of catalytic activity using phage display and proximity coupling.

27 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.071052198

Hypermutagenic PCR involving all four transitions and a sizeable proportion of transversions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.071052198

Deoxynucleoside triphosphate and pyrophosphate binding sites in the catalytically competent ternary complex for the polymerase reaction catalyzed by DNA polymerase I (Klenow fragment).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.071052198

The gene for nucleoside diphosphate kinase functions as a mutator gene in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.071052198

The effect of high-frequency random mutagenesis on in vitro protein evolution: a study on TEM-1 beta-lactamase

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31872

Use of the tetracycline promoter for the tightly regulated production of a murine antibody fragment in Escherichia coli

26 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.071052198

Production of RNA by a polymerase protein encapsulated within phospholipid vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.071052198

Thermus aquaticus DNA polymerase I mutants with altered fidelity. Interacting mutations in the O-helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.071052198

Polymerase chain reaction in liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.071052198

Effect of heparin on polymerase chain reaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.071052198

21 January 2018

Identifiers

DOI

10.1073/PNAS.071052198

1 reference

7 August 2017

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1 reference

7 August 2017

1 reference