A nonerythropoietic peptide that mimics the 3D structure of erythropoietin reduces organ injury/dysfunction and inflammation in experimental hemorrhagic shock. (Q35287077)

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English	A nonerythropoietic peptide that mimics the 3D structure of erythropoietin reduces organ injury/dysfunction and inflammation in experimental hemorrhagic shock.	scientific article

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A nonerythropoietic peptide that mimics the 3D structure of erythropoietin reduces organ injury/dysfunction and inflammation in experimental hemorrhagic shock (English)

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Nimesh S A Patel

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Anthony Cerami

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Kiran K Nandra

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Massimo Collino

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Ws Fred Wong

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Amar Kapoor

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Elisa Benetti

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Fera Y Goh

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Roberto Fantozzi

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Christoph Thiemermann

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13 May 2011

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2 February 2020

Molecular Medicine

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9-10

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883-892

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2 February 2020

https://scigraph.springernature.com/pub.10.2119/molmed.2011.00053

0 references

Cardioprotection by a nonerythropoietic, tissue-protective peptide mimicking the 3D structure of erythropoietin

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12 July 2018

Pharmacologic resuscitation promotes survival and attenuates hemorrhage-induced activation of extracellular signal-regulated kinase 1/2.

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GSK3beta promotes apoptosis after renal ischemic injury.

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12 July 2018

Molecular basis of cardioprotection by erythropoietin

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12 July 2018

The impact of erythropoietin on short-term changes in phosphorylation of brain protein kinases in a rat model of traumatic brain injury

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Emerging therapies in traumatic hemorrhage control

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12 July 2018

Insulin reduces cerebral ischemia/reperfusion injury in the hippocampus of diabetic rats: a role for glycogen synthase kinase-3beta

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12 July 2018

Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin

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12 July 2018

Erythropoietin attenuates hyperoxia-induced lung injury by down-modulating inflammation in neonatal rats

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12 July 2018

Selective modulation of the erythropoietic and tissue-protective effects of erythropoietin: time to reach the full therapeutic potential of erythropoietin

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12 July 2018

IL-3, IL-5, and GM-CSF signaling: crystal structure of the human beta-common receptor

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12 July 2018

EPO: renoprotection beyond anemia correction

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12 July 2018

The role of nitric oxide in the post-ischemic revascularization process

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12 July 2018

Discovering erythropoietin's extra-hematopoietic functions: biology and clinical promise

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Risk factors for chemotherapy-associated venous thromboembolism in a prospective observational study

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12 July 2018

Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.

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12 July 2018

Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor

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12 July 2018

Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion.

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12 July 2018

Defining the involvement of p38alpha MAPK in the production of anti- and proinflammatory cytokines using an SB 203580-resistant form of the kinase

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12 July 2018

Seven hundred fifty-three consecutive deaths in a level I trauma center: the argument for injury prevention

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The phosphoinositide 3-kinase pathway

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The IKK/NF-kappa B pathway

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12 July 2018

Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

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12 July 2018

Review article: the role of tumor necrosis factor in renal ischemia-reperfusion injury

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12 July 2018

Heparin in inflammation: potential therapeutic applications beyond anticoagulation.

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Markers for predicting the development of acute respiratory distress syndrome

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12 July 2018

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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12 July 2018

Functional erythropoietin receptor of the cells with neural characteristics. Comparison with receptor properties of erythroid cells

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12 July 2018

Erythropoietin: physiology and clinical experience.

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12 July 2018

Recombinant human erythropoietin protects against experimental spinal cord trauma injury by regulating expression of the proteins MKP-1 and p-ERK.

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26 September 2018

Protective effects of erythropoietin against acute lung injury in a rat model of acute necrotizing pancreatitis.

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26 September 2018

Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: effects of the PPAR-alpha agonist WY14643.

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26 September 2018

Pretreatment with recombined human erythropoietin attenuates ischemia-reperfusion-induced lung injury in rats.

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26 September 2018

Chronic erythropoietin treatment limits infarct-size in the myocardium in vitro

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26 September 2018

Role of p38 mitogen-activated protein kinase on renal dysfunction after hemorrhagic shock in rats

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26 September 2018

GSK-3beta inhibitors attenuate the organ injury/dysfunction caused by endotoxemia in the rat.

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26 September 2018

Mechanisms of erythropoietin-mediated cardioprotection during ischemia-reperfusion injury: role of protein kinase C and phosphatidylinositol 3-kinase signaling

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26 September 2018

Erythropoietin attenuates the tissue injury associated with hemorrhagic shock and myocardial ischemia.

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26 September 2018

The Attenuation of Hemorrhage-Induced Liver Injury by Exogenous Nitric Oxide, L -Arginine, and Inhibition of Inducible Nitric Oxide Synthase

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A novel, potent and selective inhibitor of the activity of inducible nitric oxide synthase (GW274150) reduces the organ injury in hemorrhagic shock.

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Early predictors of postinjury multiple organ failure

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Recombinant human erythropoietin protects the liver from hepatic ischemia-reperfusion injury in the rat

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31 March 2020

Improved survival of critically ill trauma patients treated with recombinant human erythropoietin

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31 March 2020

Mechanism of estrogen-mediated attenuation of hepatic injury following trauma-hemorrhage: Akt-dependent HO-1 up-regulation

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31 March 2020

Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms

1 reference

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31 March 2020

Erythropoietin affords additional cardioprotection to preconditioned hearts by enhanced phosphorylation of glycogen synthase kinase-3 beta

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31 March 2020

Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor

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31 March 2020

Insulin reduces the multiple organ injury and dysfunction caused by coadministration of lipopolysaccharide and peptidoglycan independently of blood glucose: Role of glycogen synthase kinase-3β inhibition*

1 reference

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31 March 2020

Role of glycogen synthase kinase-3 in TNF-alpha-induced NF-kappaB activation and apoptosis in hepatocytes

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31 March 2020

β Common receptor integrates the erythropoietin signaling in activation of endothelial nitric oxide synthase

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31 March 2020

Role of p38 mitogen-activated protein kinase on cardiac dysfunction after hemorrhagic shock in rats

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31 March 2020

Role of tumor necrosis factor-alpha and interleukin-1beta on lung dysfunction following hemorrhagic shock in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21607291

12 December 2020

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10.2119/MOLMED.2011.00053

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2 February 2020

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2 February 2020

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