Quantitative mass spectrometry reveals dynamics of factor-inhibiting hypoxia-inducible factor-catalyzed hydroxylation. (Q35311217)

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9 February 2020

title

Quantitative mass spectrometry reveals dynamics of factor-inhibiting hypoxia-inducible factor-catalyzed hydroxylation (English)

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9 February 2020

4

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9 February 2020

Rachelle S Singleton

1

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9 February 2020

Roman Fischer

3

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9 February 2020

Peter J. Ratcliffe

5

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9 February 2020

Matthew Cockman

6

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9 February 2020

author name string

David C Trudgian

2

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9 February 2020

language of work or name

English

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publication date

30 July 2011

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Journal of Biological Chemistry

9 February 2020

published in

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9 February 2020

volume

286

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9 February 2020

issue

39

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9 February 2020

page(s)

33784-33794

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Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors

9 February 2020

cites work

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Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains

27 July 2018

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Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor

27 July 2018

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Consequences of IkappaB alpha hydroxylation by the factor inhibiting HIF (FIH)

27 July 2018

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The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism

27 July 2018

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Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents

27 July 2018

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FIH-dependent asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.

27 July 2018

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Asparagine beta-hydroxylation stabilizes the ankyrin repeat domain fold

27 July 2018

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Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.

27 July 2018

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Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways

27 July 2018

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ASB4 is a hydroxylation substrate of FIH and promotes vascular differentiation via an oxygen-dependent mechanism

27 July 2018

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Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor

27 July 2018

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Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry

27 July 2018

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Ankyrin repeat: a unique motif mediating protein-protein interactions.

27 July 2018

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Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

27 July 2018

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Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay

27 July 2018

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General framework for developing and evaluating database scoring algorithms using the TANDEM search engine

27 July 2018

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Proteomic analyses using an accurate mass and time tag strategy

27 July 2018

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27 July 2018

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Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].

27 July 2018

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Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases

27 July 2018

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27 July 2018

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27 July 2018

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FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

27 July 2018

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Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

27 July 2018

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FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

27 July 2018

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

27 July 2018

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Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

27 July 2018

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MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH)

21 January 2018

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Hypoxia-dependent sequestration of an oxygen sensor by a widespread structural motif can shape the hypoxic response--a predictive kinetic model

21 January 2018

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Differences in hydroxylation and binding of Notch and HIF-1alpha demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1).

21 January 2018

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Monoclonal antibody-based screening assay for factor inhibiting hypoxia-inducible factor inhibitors

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Asparaginyl beta-hydroxylation of proteins containing ankyrin repeat domains influences their stability and function.

21 January 2018

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M111.262808

Identifiers

DOI

10.1074/JBC.M111.262808

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808058%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

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9 February 2020

PubMed publication ID

21808058

1 reference