Apoptotic events induced by high glucose in human hepatoma HepG2 cells involve endoplasmic reticulum stress and MAPK's activation (Q35313600)

7 August 2017

Apoptotic events induced by high glucose in human hepatoma HepG2 cells involve endoplasmic reticulum stress and MAPK's activation (English)

1 reference

7 August 2017

endoplasmic reticulum

0 references

hepatocellular carcinoma

1 reference

1 reference

Qiaoling Jiang

1

1 reference

7 August 2017

Yujun Yuan

2

1 reference

7 August 2017

Jiali Zhou

3

1 reference

7 August 2017

Yan Wu

4

1 reference

7 August 2017

Qing Zhou

5

1 reference

7 August 2017

Shuyu Gui

6

1 reference

7 August 2017

Yuan Wang

7

1 reference

7 August 2017

9 October 2014

1 reference

Molecular and Cellular Biochemistry

7 August 2017

1 reference

7 August 2017

399

1 reference

7 August 2017

1-2

1 reference

7 August 2017

113-122

1 reference

https://scigraph.springernature.com/pub.10.1007/s11010-014-2238-5

7 August 2017

0 references

cites work

National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

High glucose induces podocyte apoptosis by stimulating TRPC6 via elevation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

The hyperglycemia stimulated myocardial endoplasmic reticulum (ER) stress contributes to diabetic cardiomyopathy in the transgenic non-obese type 2 diabetic rats: a differential role of unfolded protein response (UPR) signaling proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Effects of high glucose concentration on the barrier function and the expression of tight junction proteins in human retinal pigment epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Mediators of endoplasmic reticulum stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Attenuation of CHOP-mediated myocardial apoptosis in pressure-overloaded dominant negative p38α mitogen-activated protein kinase mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

New directions in ER stress-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

The ASK1-MAP kinase cascades in mammalian stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

ER stress signaling and the BCL-2 family of proteins: from adaptation to irreversible cellular damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Caspase-2 and JNK activated by saturated fatty acids are not involved in apoptosis induction but modulate ER stress in human pancreatic β-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Bip overexpression, but not CHOP inhibition, attenuates fatty-acid-induced endoplasmic reticulum stress and apoptosis in HepG2 liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

GRP78, but Not Protein-disulfide Isomerase, Partially Reverses Hyperglycemia-induced Inhibition of Insulin Synthesis and Secretion in Pancreatic {beta}-Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Signal integration in the endoplasmic reticulum unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Apoptosis in HepG2 cells exposed to high glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Glucose increases hepatic lipase expression in HepG2 liver cells through upregulation of upstream stimulatory factors 1 and 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Endoplasmic reticulum stress in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Decreased expression of endoplasmic reticulum chaperone GRP78 in liver of diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Roles of CHOP/GADD153 in endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

The effects of α-lipoic acid on liver oxidative stress and free fatty acid composition in methionine-choline deficient diet-induced NAFLD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Effects of α-lipoic acid and L-carnosine supplementation on antioxidant activities and lipid profiles in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Alpha-lipoic acid attenuates adipocyte differentiation and lipid accumulation in 3T3-L1 cells via AMPK-dependent autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Mechanisms of acetaminophen toxicity: immunochemical detection of drug-protein adducts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Direct and indirect antioxidant properties of α-lipoic acid and therapeutic potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Redox signaling loops in the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Integration of the unfolded protein and oxidative stress responses through SKN-1/Nrf

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Co-involvement of mitochondria and endoplasmic reticulum in regulation of apoptosis: changes in cytochrome c, Bcl-2 and Bax in the hippocampus of aluminum-treated rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Reactive oxygen species and the regulation of cell death by the Bcl-2 gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Prolonged activation of ERK triggers glutamate-induced apoptosis of astrocytes: neuroprotective effect of FK506.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11010-014-2238-5

Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation

21 January 2018

1 reference

12 December 2020

Requirement of activation of JNK and p38 for environmental stress-induced erythroid differentiation and apoptosis and of inhibition of ERK for apoptosis

1 reference

12 December 2020

Alternative functions of the BCL-2 protein family at the endoplasmic reticulum

1 reference

12 December 2020

Integration of ER stress, oxidative stress and the inflammatory response in health and disease

1 reference

12 December 2020

Caspase-3 activation is a critical determinant of genotoxic stress-induced apoptosis

1 reference

12 December 2020

Insights in the mechanism underlying the protective effect of α-lipoic acid against acetaminophen-hepatotoxicity

1 reference

12 December 2020

Modulation of AT-1R/CHOP-JNK-Caspase12 pathway by olmesartan treatment attenuates ER stress-induced renal apoptosis in streptozotocin-induced diabetic mice

1 reference

12 December 2020

The role of proteases during apoptosis.

1 reference

12 December 2020

Type 2 diabetes mellitus as a conformational disease

1 reference

12 December 2020

10.1007/S11010-014-2238-5

Identifiers

DOI

1 reference

7 August 2017

1 reference