Impairment of lon-induced protection against the accumulation of oxidized proteins in senescent wi-38 fibroblasts (Q35349328)

7 August 2017

title

Impairment of lon-induced protection against the accumulation of oxidized proteins in senescent wi-38 fibroblasts (English)

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7 August 2017

Jenny K Ngo

1

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7 August 2017

Laura C D Pomatto

2

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7 August 2017

Daniela A Bota

3

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7 August 2017

Alison L Koop

4

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7 August 2017

Kelvin J A Davies

5

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7 August 2017

language of work or name

English

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publication date

24 August 2011

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The Journals of Gerontology

7 August 2017

published in

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7 August 2017

volume

66

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7 August 2017

issue

11

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7 August 2017

page(s)

1178-1185

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Protein modification and replicative senescence of WI-38 human embryonic fibroblasts.

7 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193527

Mitochondrial Lon protease is a human stress protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193527

Protein oxidative modifications and replicative senescence of WI-38 human embryonic fibroblasts.

12 July 2018

1 reference

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Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance

12 July 2018

1 reference

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Mitochondrial protein oxidation and degradation in response to oxidative stress and aging

12 July 2018

1 reference

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Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis

12 July 2018

1 reference

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Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193527

12 July 2018

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Efficacy of MitoTracker Green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues

12 July 2018

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Mild heat stress stimulates 20S proteasome and its 11S activator in human fibroblasts undergoing aging in vitro

12 July 2018

1 reference

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The peptide methionine sulfoxide reductases, MsrA and MsrB (hCBS-1), are downregulated during replicative senescence of human WI-38 fibroblasts

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193527

Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix

12 July 2018

1 reference

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Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193527

Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism

12 July 2018

1 reference

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Role of oxidative stress and protein oxidation in the aging process

12 July 2018

1 reference

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Cellular senescence as a tumor-suppressor mechanism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193527

Degradation of oxidized proteins by the 20S proteasome.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193527

Gene expression profile of aging and its retardation by caloric restriction

12 July 2018

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Enhanced mitochondrial biogenesis is associated with increased expression of the mitochondrial ATP-dependent Lon protease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193527

Protein oxidation in aging, disease, and oxidative stress

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193527

Degradation of oxidized proteins in mammalian cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193527

Oxidative stress: the paradox of aerobic life

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193527

PIM1 encodes a mitochondrial ATP-dependent protease that is required for mitochondrial function in the yeast Saccharomyces cerevisiae.

12 July 2018

1 reference

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Requirement for the yeast gene LON in intramitochondrial proteolysis and maintenance of respiration.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193527

Oxidative damage and mitochondrial decay in aging

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193527

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193527

Modulation of Lon protease activity and aconitase turnover during aging and oxidative stress.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193527

Different kinetics of senescence in human fibroblasts and peritoneal mesothelial cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3193527

Increase of oxidatively modified protein is associated with a decrease of proteasome activity and content in aging epidermal cells

26 September 2018

1 reference

12 December 2020

The role of protein quality control in mitochondrial protein homeostasis under oxidative stress

1 reference

12 December 2020

1 reference

12 December 2020

Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice

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12 December 2020

Identifiers

DOI

10.1093/GERONA/GLR145

1 reference

7 August 2017

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7 August 2017

1 reference