Increased frequency of regulatory T cells accompanies increased immune activation in rectal mucosae of HIV-positive noncontrollers (Q35363011)

7 August 2017

title

Increased frequency of regulatory T cells accompanies increased immune activation in rectal mucosae of HIV-positive noncontrollers (English)

1 reference

7 August 2017

8

Steven G Deeks

1 reference

7 August 2017

Julia M Shaw

1

1 reference

7 August 2017

Peter W Hunt

2

1 reference

7 August 2017

J William Critchfield

3

1 reference

7 August 2017

Delandy H McConnell

4

1 reference

7 August 2017

Juan Carlos Garcia

5

1 reference

7 August 2017

Richard B Pollard

6

1 reference

7 August 2017

Ma Somsouk

7

1 reference

7 August 2017

Barbara L Shacklett

9

1 reference

7 August 2017

language of work or name

English

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publication date

31 August 2011

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7 August 2017

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7 August 2017

volume

85

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7 August 2017

issue

21

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7 August 2017

page(s)

11422-11434

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Innate and adaptive immune responses both contribute to pathological CD4 T cell activation in HIV-1 infected Ugandans

7 August 2017

cites work

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A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers

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Disruption of intestinal CD4+ T cell homeostasis is a key marker of systemic CD4+ T cell activation in HIV-infected individuals

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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OX40 is required for regulatory T cell-mediated control of colitis

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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CD4(+)CD25(+/hi)CD127(lo) phenotype does not accurately identify regulatory T cells in all populations of HIV-infected persons

12 July 2018

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Inhibitory TCR coreceptor PD-1 is a sensitive indicator of low-level replication of SIV and HIV-1

12 July 2018

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Human regulatory T cells are targets for human immunodeficiency Virus (HIV) infection, and their susceptibility differs depending on the HIV type 1 strain

12 July 2018

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Mechanisms of foxp3+ T regulatory cell-mediated suppression

12 July 2018

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Mucosal immunity to HIV: a review of recent literature

12 July 2018

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HIV-1 binding to CD4 on CD4+CD25+ regulatory T cells enhances their suppressive function and induces them to home to, and accumulate in, peripheral and mucosal lymphoid tissues: an additional mechanism of immunosuppression

12 July 2018

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12 July 2018

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Level, phenotype and activation status of CD4+FoxP3+regulatory T cells in patients chronically infected with human immunodeficiency virus and/or hepatitis C virus

12 July 2018

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Foxp3 and Treg cells in HIV-1 infection and immuno-pathogenesis

12 July 2018

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Suppression of HIV-specific and allogeneic T cell activation by human regulatory T cells is dependent on the strength of signals

12 July 2018

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Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

12 July 2018

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Preservation of FoxP3+ regulatory T cells in the peripheral blood of human immunodeficiency virus type 1-infected elite suppressors correlates with low CD4+ T-cell activation.

12 July 2018

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How regulatory T cells work

12 July 2018

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12 July 2018

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Regulatory T cells inhibit dendritic cells by lymphocyte activation gene-3 engagement of MHC class II.

12 July 2018

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12 July 2018

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CD127 and CD25 expression defines CD4+ T cell subsets that are differentially depleted during HIV infection

12 July 2018

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HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Regulatory T-cell markers, indoleamine 2,3-dioxygenase, and virus levels in spleen and gut during progressive simian immunodeficiency virus infection

12 July 2018

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Suppression of HIV-specific T cell activity by lymph node CD25+ regulatory T cells from HIV-infected individuals

12 July 2018

1 reference

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Strong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removal

12 July 2018

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Microbial translocation is a cause of systemic immune activation in chronic HIV infection

12 July 2018

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Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation

12 July 2018

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HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS.

12 July 2018

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CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

12 July 2018

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Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

12 July 2018

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HIV disease: fallout from a mucosal catastrophe?

12 July 2018

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Perils at mucosal front lines for HIV and SIV and their hosts

12 July 2018

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Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

12 July 2018

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12 July 2018

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Depletion of regulatory T cells in HIV infection is associated with immune activation

12 July 2018

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Early antiretroviral therapy for simian immunodeficiency virus infection leads to mucosal CD4+ T-cell restoration and enhanced gene expression regulating mucosal repair and regeneration

12 July 2018

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Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells

12 July 2018

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12 July 2018

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12 July 2018

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CD25(+)CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status

12 July 2018

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12 July 2018

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Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens

12 July 2018

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Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy

12 July 2018

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Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis

12 July 2018

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Trafficking of human immunodeficiency virus type 1-specific CD8+ T cells to gut-associated lymphoid tissue during chronic infection

12 July 2018

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An essential role for Scurfin in CD4+CD25+ T regulatory cells

12 July 2018

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

12 July 2018

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Control of regulatory T cell development by the transcription factor Foxp3

12 July 2018

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Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function.

12 July 2018

1 reference

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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

12 July 2018

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

12 July 2018

1 reference

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JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome

12 July 2018

1 reference

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Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage.

12 July 2018

1 reference

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Gastrointestinal T lymphocytes retain high potential for cytokine responses but have severe CD4(+) T-cell depletion at all stages of simian immunodeficiency virus infection compared to peripheral lymphocytes

12 July 2018

1 reference

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Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

12 July 2018

1 reference

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

12 July 2018

1 reference

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Infectious immunological tolerance

12 July 2018

1 reference

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Cell interactions in the induction of tolerance: the role of thymic lymphocytes

12 July 2018

1 reference

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High levels of human antigen-specific CD4+ T cells in peripheral blood revealed by stimulated coexpression of CD25 and CD134 (OX40).

12 July 2018

1 reference

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Proliferation of weakly suppressive regulatory CD4+ T cells is associated with over-active CD4+ T-cell responses in HIV-positive patients with mycobacterial immune restoration disease.

26 September 2018

1 reference

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Regulatory T cells in HIV infection: pathogenic or protective participants in the immune response?

26 September 2018

1 reference

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Peripheral CD4 loss of regulatory T cells is associated with persistent viraemia in chronic HIV infection

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194952

Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194952

Regulatory T cells generated during cytomegalovirus in vitro stimulation of mononuclear cells from HIV-infected individuals on HAART correlate with decreased lymphocyte proliferation.

26 September 2018

1 reference

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Mucosal but not peripheral FOXP3+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART.

26 September 2018

1 reference

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Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection

26 September 2018

1 reference

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Persistence of naive CD45RA+ regulatory T cells in adult life.

26 September 2018

1 reference

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Relationship of CD4+CD25+ regulatory T cells to immune status in HIV-infected patients.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194952

Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194952

The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients.

26 September 2018

1 reference

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Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients

26 September 2018

1 reference

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Cutting edge: human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells

26 September 2018

1 reference

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CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load.

26 September 2018

1 reference

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Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194952

Spectral compensation for flow cytometry: visualization artifacts, limitations, and caveats.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194952

Dysregulation of interleukin-7 receptor may generate loss of cytotoxic T cell response in human immunodeficiency virus type 1 infection

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194952

Expansion of FOXP3+ CD8 T cells with suppressive potential in colorectal mucosa following a pathogenic simian immunodeficiency virus infection correlates with diminished antiviral T cell response and viral control

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194952

CD4+CD25high regulatory cells in human peripheral blood

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194952

Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194952

Cutting Edge: TNFR-Shedding by CD4+CD25+ Regulatory T Cells Inhibits the Induction of Inflammatory Mediators

15 November 2018

1 reference

12 December 2020

Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4+ cell count, soluble immune activation markers, or combinations of

1 reference

12 December 2020

Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level

1 reference

12 December 2020

Abnormal presence of semimature dendritic cells that induce regulatory T cells in HIV-infected subjects

1 reference

12 December 2020

Relationship of frequency of CD4+CD25+Foxp3+ regulatory T cells with disease progression in antiretroviral-naive HIV-1 infected Chinese

1 reference

12 December 2020

The decrease of regulatory T cells correlates with excessive activation and apoptosis of CD8+ T cells in HIV-1-infected typical progressors, but not in long-term non-progressors

1 reference

12 December 2020

Impact of changes in antigen level on CD38/PD-1 co-expression on HIV-specific CD8 T cells in chronic, untreated HIV-1 infection

1 reference

12 December 2020

CD25+ regulatory T cells isolated from HIV-infected individuals suppress the cytolytic and nonlytic antiviral activity of HIV-specific CD8+ T cells in vitro

1 reference

12 December 2020

Identifiers

DOI

10.1128/JVI.05608-11

1 reference

release_liyjxdgbdncqfb6q6damuxfxri

7 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/liyjxdgbdncqfb6q6damuxfxri

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3194952

1 reference

7 August 2017

1 reference