p38 MAPK-mediated regulation of Xbp1s is crucial for glucose homeostasis (Q35419603)

8 August 2017

p38 MAPK-mediated regulation of Xbp1s is crucial for glucose homeostasis (English)

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8 August 2017

Jaemin Lee

1

1 reference

8 August 2017

Cheng Sun

2

1 reference

8 August 2017

Yingjiang Zhou

3

1 reference

8 August 2017

Justin Lee

4

1 reference

8 August 2017

Deniz Gokalp

5

1 reference

8 August 2017

Hilde Herrema

6

1 reference

8 August 2017

Sang Won Park

7

1 reference

8 August 2017

Roger J Davis

8

1 reference

8 August 2017

Umut Ozcan

9

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8 August 2017

language of work or name

English

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publication date

4 September 2011

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8 August 2017

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8 August 2017

17

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8 August 2017

10

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8 August 2017

1251-1260

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https://scigraph.springernature.com/pub.10.1038/nm.2449

8 August 2017

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cites work

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JNK1 and IKKbeta: molecular links between obesity and metabolic dysfunction

27 July 2018

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TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.

27 July 2018

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Tocotrienols induce apoptosis in breast cancer cell lines via an endoplasmic reticulum stress-dependent increase in extrinsic death receptor signaling

27 July 2018

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p38(MAPK): stress responses from molecular mechanisms to therapeutics

27 July 2018

1 reference

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Post-transcriptional gene regulation by MAP kinases via AU-rich elements

27 July 2018

1 reference

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Protective effect against Parkinson's disease-related insults through the activation of XBP1

27 July 2018

1 reference

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XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

27 July 2018

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Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis

27 July 2018

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JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity

27 July 2018

1 reference

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Signal integration in the endoplasmic reticulum unfolded protein response

27 July 2018

1 reference

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Endoplasmic reticulum stress signaling in disease

27 July 2018

1 reference

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Inflammation and insulin resistance

27 July 2018

1 reference

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Intracellular signaling by the unfolded protein response

27 July 2018

1 reference

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The mammalian unfolded protein response

27 July 2018

1 reference

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The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes.

27 July 2018

1 reference

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IKK-beta links inflammation to obesity-induced insulin resistance

27 July 2018

1 reference

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Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals

27 July 2018

1 reference

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Mechanism of p38 MAP kinase activation in vivo.

27 July 2018

1 reference

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A central role for JNK in obesity and insulin resistance

27 July 2018

1 reference

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Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice.

27 July 2018

1 reference

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The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

MAP kinases in the immune response

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines

27 July 2018

1 reference

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Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

Mammalian MAP kinase signalling cascades

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

27 July 2018

1 reference

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MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

An essential role for XBP-1 in host protection against immune activation in C. elegans

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

Macrophages, inflammation, and insulin resistance

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

Endoplasmic reticulum stress plays a central role in development of leptin resistance

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

IRE1 signaling affects cell fate during the unfolded protein response

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

Targeting XBP-1 as a novel anti-cancer strategy.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

Involvement of endoplasmic reticulum stress in insulin resistance and diabetes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

Proteasome inhibitors disrupt the unfolded protein response in myeloma cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

The basic domain/leucine zipper protein hXBP-1 preferentially binds to and transactivates CRE-like sequences containing an ACGT core

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397266

Phospholipid biosynthesis program underlying membrane expansion during B-lymphocyte differentiation

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21892182

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NM.2449

1 reference

Dimensions Publication ID

8 August 2017

0 references

1 reference

8 August 2017

1 reference