Tau-dependent Kv4.2 depletion and dendritic hyperexcitability in a mouse model of Alzheimer's disease (Q35423803)

8 August 2017

Tau-dependent Kv4.2 depletion and dendritic hyperexcitability in a mouse model of Alzheimer's disease (English)

1 reference

8 August 2017

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25878292%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Susan C Buckingham

3

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9 June 2020

Dax Hoffman

7

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9 June 2020

Erik D. Roberson

8

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9 June 2020

author name string

Alicia M Hall

1

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9 June 2020

Sean J Markwardt

4

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9 June 2020

Yin Peng

5

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9 June 2020

Qin Wang

6

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9 June 2020

language of work or name

English

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publication date

1 April 2015

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8 August 2017

Journal of Neuroscience

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9 June 2020

volume

35

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9 June 2020

issue

15

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9 June 2020

page(s)

6221-6230

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describes a project that uses

9 June 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4397611/fullTextXML

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inferred from PubMed Central ID database lookup

cites work

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Bidirectional regulation of dendritic voltage-gated potassium channels by the fragile X mental retardation protein

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Alterations of A-type potassium channels in hippocampal neurons after traumatic brain injury

12 July 2018

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Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2.

12 July 2018

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Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.

12 July 2018

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Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

12 July 2018

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12 July 2018

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Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease

12 July 2018

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Loss of neprilysin function promotes amyloid plaque formation and causes cerebral amyloid angiopathy

12 July 2018

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12 July 2018

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Kv4 potassium channel subunits control action potential repolarization and frequency-dependent broadening in rat hippocampal CA1 pyramidal neurones

12 July 2018

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12 July 2018

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12 July 2018

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Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

12 July 2018

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Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits

12 July 2018

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A postsynaptic transient K(+) current modulated by arachidonic acid regulates synaptic integration and threshold for LTP induction in hippocampal pyramidal cells

12 July 2018

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Dendritic K+ channels contribute to spike-timing dependent long-term potentiation in hippocampal pyramidal neurons

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Differential expression of K+ channel mRNAs in the rat brain and down-regulation in the hippocampus following seizures

12 July 2018

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Dendritic structural degeneration is functionally linked to cellular hyperexcitability in a mouse model of Alzheimer's disease.

12 July 2018

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26 September 2018

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Quantifying biomarkers of cognitive dysfunction and neuronal network hyperexcitability in mouse models of Alzheimer's disease: depletion of calcium-dependent proteins and inhibitory hippocampal remodeling

26 September 2018

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Cortical excitability in very mild Alzheimer's disease: a long-term follow-up study

26 September 2018

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Expression and localization of voltage dependent potassium channel Kv4.2 in epilepsy associated focal lesions.

26 September 2018

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Abeta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks

26 September 2018

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Altered synaptic and non-synaptic properties of CA1 pyramidal neurons in Kv4.2 knockout mice

26 September 2018

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Altered phosphorylation and localization of the A-type channel, Kv4.2 in status epilepticus

26 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397611

Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397611

Functional properties and oxidative modulation of A-type K currents in hippocampal granule cells of control and chronically epileptic rats

26 September 2018

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Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease.

26 September 2018

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Functional role of the fast transient outward K+ current IA in pyramidal neurons in (rat) primary visual cortex.

26 September 2018

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Postsynaptic and extrasynaptic localization of Kv4.2 channels in the mouse hippocampal region, with special reference to targeted clustering at gabaergic synapses

26 September 2018

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Dendrite and dendritic spine alterations in Alzheimer models

26 September 2018

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Acquired dendritic channelopathy in temporal lobe epilepsy

26 September 2018

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Co-expression of multiple transgenes in mouse CNS: a comparison of strategies.

26 September 2018

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Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397611

Role of an A-type K+ conductance in the back-propagation of action potentials in the dendrites of hippocampal pyramidal neurons.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397611

Targeted deletion of Kv4.2 eliminates I(to,f) and results in electrical and molecular remodeling, with no evidence of ventricular hypertrophy or myocardial dysfunction

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25878292

inferred from PubMed ID database lookup

12 December 2020

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Identifiers

DOI

10.1523/JNEUROSCI.2552-14.2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25878292%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25878292%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference