The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections. (Q35490893)

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English	The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections.	scientific article

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7 February 2020

The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections (English)

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7 February 2020

atopic dermatitis

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7 February 2020

Mark Boguniewicz

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Mark Boguniewicz

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Jon M Hanifin

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Lynda C. Schneider

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Lynda C Schneider

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Lisa A Beck

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7 February 2020

Donald Y M Leung

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Donald Y M Leung

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Tissa R Hata

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Kathleen C Barnes

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Kathleen C Barnes

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7 February 2020

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Michael D Howell

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Peisong Gao

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Byung Eui Kim

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7 February 2020

Leighann J Lesley

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7 February 2020

Joanne E Streib

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7 February 2020

Patricia A Taylor

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7 February 2020

Daniel J Zaccaro

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18 July 2011

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7 February 2020

The Journal of Allergy and Clinical Immunology

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1006-1014

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7 February 2020

Human atopic dermatitis complicated by eczema herpeticum is associated with abnormalities in IFN-γ response

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12 July 2018

Genetic variants in thymic stromal lymphopoietin are associated with atopic dermatitis and eczema herpeticum.

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IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation

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Recent insights into atopic dermatitis and implications for management of infectious complications

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Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum.

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12 July 2018

An IgE-associated polymorphism in STAT6 alters NF-kappaB binding, STAT6 promoter activity, and mRNA expression

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12 July 2018

Phenotype of atopic dermatitis subjects with a history of eczema herpeticum.

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Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus

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Constitutively active STAT6 predisposes toward a lymphoproliferative disorder

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The role of human beta defensins and cathelicidins in atopic dermatitis

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12 July 2018

IL-4 and IL-13 negatively regulate TNF-alpha- and IFN-gamma-induced beta-defensin expression through STAT-6, suppressor of cytokine signaling (SOCS)-1, and SOCS-3.

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12 July 2018

Innate immune defects in atopic dermatitis

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Association of a STAT 6 haplotype with elevated serum IgE levels in a population based cohort of white adults

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12 July 2018

New insights into atopic dermatitis

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Expression of mouse interleukin-4 by a recombinant ectromelia virus suppresses cytolytic lymphocyte responses and overcomes genetic resistance to mousepox.

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Interleukin-4/STAT6 represses STAT1 and NF-kappa B-dependent transcription through distinct mechanisms.

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Essential role of Stat6 in IL-4 signalling

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Cytokine milieu of atopic dermatitis skin subverts the innate immune response to vaccinia virus

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26 September 2018

Variation in dinucleotide (GT) repeat sequence in the first exon of the STAT6 gene is associated with atopic asthma and differentially regulates the promoter activity in vitro

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26 September 2018

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Polymorphism in the STAT6 gene encodes risk for nut allergy

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Expression of a constitutively active Stat6 in vivo alters lymphocyte homeostasis with distinct effects in T and B cells

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Impaired IL-13-mediated functions of macrophages in STAT6-deficient mice

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Genome-wide search for asthma susceptibility loci in a founder population. The Collaborative Study on the Genetics of Asthma

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Standardization and validation issues of the ELISPOT assay

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10.1016/J.JACI.2011.06.003

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7 February 2020

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7 February 2020

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7 February 2020

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