Synergistic inhibition of colon carcinoma cell growth by Hedgehog-Gli1 inhibitor arsenic trioxide and phosphoinositide 3-kinase inhibitor LY294002. (Q35531884)

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scientific article published on 17 April 2015

Language	Label	Description	Also known as
English	Synergistic inhibition of colon carcinoma cell growth by Hedgehog-Gli1 inhibitor arsenic trioxide and phosphoinositide 3-kinase inhibitor LY294002.	scientific article published on 17 April 2015

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 August 2017

Synergistic inhibition of colon carcinoma cell growth by Hedgehog-Gli1 inhibitor arsenic trioxide and phosphoinositide 3-kinase inhibitor LY294002. (English)

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Europe PubMed Central

PubMed publication ID

8 August 2017

arsenic trioxide

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colon carcinoma

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based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Xinyi Cai

1

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Europe PubMed Central

PubMed publication ID

8 August 2017

Kun Yu

2

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8 August 2017

Lijuan Zhang

3

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8 August 2017

Yunfeng Li

4

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8 August 2017

Qiang Li

5

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PubMed publication ID

8 August 2017

Zhibin Yang

6

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8 August 2017

Tao Shen

7

1 reference

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PubMed publication ID

8 August 2017

Lincan Duan

8

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8 August 2017

Wei Xiong

9

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8 August 2017

Weiya Wang

10

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8 August 2017

language of work or name

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publication date

17 April 2015

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8 August 2017

OncoTargets and Therapy

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8 August 2017

8

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PubMed publication ID

8 August 2017

877-883

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Europe PubMed Central

PubMed publication ID

8 August 2017

copyright license

Creative Commons Attribution-NonCommercial 3.0 Unported

1 April 2015

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April 2022 Public Data File from Crossref

copyright status

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Targeting hedgehog signaling in cancer: research and clinical developments

1 reference

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The mechanisms of Hedgehog signalling and its roles in development and disease

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Overlapping activities of TGF-β and Hedgehog signaling in cancer: therapeutic targets for cancer treatment.

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Toward a systems-level understanding of the Hedgehog signaling pathway: defining the complex, robust, and fragile

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12 July 2018

Developmental pathways in colon cancer: crosstalk between WNT, BMP, Hedgehog and Notch

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Hedgehog pathway and GLI1 isoforms in human cancer.

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The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer

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The current landscape of locally advanced rectal cancer

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Gli proteins in development and disease

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Hedgehog signaling pathway as a therapeutic target in various types of cancer

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Hallmarks of Cancer: The Next Generation

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Hedgehog signaling drives cellular survival in human colon carcinoma cells

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Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector

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12 July 2018

Hedgehog signaling and gastrointestinal cancer

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12 July 2018

Hedgehog beyond medulloblastoma and basal cell carcinoma

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Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407746

12 July 2018

Hedgehog signalling in colon cancer and stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407746

12 July 2018

Inhibition of the hedgehog pathway in advanced basal-cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407746

12 July 2018

Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

1 reference

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12 July 2018

Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade

1 reference

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12 July 2018

Inhibition of p70S6K2 down-regulates Hedgehog/GLI pathway in non-small cell lung cancer cell lines

1 reference

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12 July 2018

Co-activation of hedgehog and AKT pathways promote tumorigenesis in zebrafish

1 reference

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12 July 2018

Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway

1 reference

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12 July 2018

Hedgehog: functions and mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407746

12 July 2018

The Gli code: an information nexus regulating cell fate, stemness and cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407746

12 July 2018

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

1 reference

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12 July 2018

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.

1 reference

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12 July 2018

Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling

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12 July 2018

Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions.

1 reference

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12 July 2018

In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins

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12 July 2018

Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells

1 reference

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26 September 2018

Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25945059

12 December 2020

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10.2147/OTT.S71034

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Europe PubMed Central

PubMed publication ID

8 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

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