A conserved PTEN/FOXO pathway regulates neuronal morphology during C. elegans development (Q35534634)

8 August 2017

A conserved PTEN/FOXO pathway regulates neuronal morphology during C. elegans development (English)

1 reference

8 August 2017

Caenorhabditis elegans

0 references

author name string

Ryan Christensen

1

1 reference

8 August 2017

Luis de la Torre-Ubieta

2

1 reference

8 August 2017

Azad Bonni

3

1 reference

8 August 2017

Daniel A Colón-Ramos

4

1 reference

8 August 2017

language of work or name

English

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publication date

1 December 2011

1 reference

8 August 2017

11

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inferred from page(s)

published in

Development

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8 August 2017

138

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8 August 2017

23

1 reference

8 August 2017

5257-5267

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Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported

8 August 2017

start time

5 September 2020

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Regulation of neuronal cell death by MST1-FOXO1 signaling

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Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice

27 July 2018

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FOXO animal models reveal a variety of diverse roles for FOXO transcription factors

27 July 2018

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Function of PTEN during the formation and maintenance of neuronal circuits in the brain

27 July 2018

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Glia promote local synaptogenesis through UNC-6 (netrin) signaling in C. elegans

27 July 2018

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Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase

27 July 2018

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Phosphoinositide 3-kinase signalling events controlling axonal morphogenesis

27 July 2018

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Insulin-like signaling and the neural circuit for integrative behavior in C. elegans

27 July 2018

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Insulin signaling in the central nervous system: learning to survive

27 July 2018

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A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

27 July 2018

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Pten regulates neuronal arborization and social interaction in mice

27 July 2018

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UNC-6/Netrin induces neuronal asymmetry and defines the site of axon formation

27 July 2018

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

27 July 2018

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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

27 July 2018

1 reference

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Inhibition of neuronal phenotype by PTEN in PC12 cells

27 July 2018

1 reference

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mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo

27 July 2018

1 reference

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Investigating C. elegans development through mosaic analysis

27 July 2018

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The phosphatidylinositol-3 kinase (PI3K)-Akt pathway suppresses neurite branch formation in NGF-treated PC12 cells

27 July 2018

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Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors

27 July 2018

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Interfacial kinetic analysis of the tumour suppressor phosphatase, PTEN: evidence for activation by anionic phospholipids

27 July 2018

1 reference

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Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

A role for nuclear PTEN in neuronal differentiation.

27 July 2018

1 reference

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A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans

27 July 2018

1 reference

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

27 July 2018

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Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

27 July 2018

1 reference

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daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

27 July 2018

1 reference

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The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

27 July 2018

1 reference

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Regulation of interneuron function in the C. elegans thermoregulatory pathway by the ttx-3 LIM homeobox gene

27 July 2018

1 reference

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Phosphoinositide 3-kinases: a conserved family of signal transducers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Germline mutations in PTEN are present in Bannayan-Zonana syndrome.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

A family of phosphoinositide 3-kinases in Drosophila identifies a new mediator of signal transduction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Neural regulation of thermotaxis in Caenorhabditis elegans

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

PTEN suppression promotes neurite development exclusively in differentiating PC12 cells via PI3-kinase and MAP kinase signaling.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Aging-dependent and -independent modulation of associative learning behavior by insulin/insulin-like growth factor-1 signal in Caenorhabditis elegans.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Lifespan and dauer regulation by tissue-specific activities of Caenorhabditis elegans DAF-18.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Pten loss causes hypertrophy and increased proliferation of astrocytes in vivo

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Genomic cis-regulatory architecture and trans-acting regulators of a single interneuron-specific gene battery in C. elegans.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

A regulatory cascade of three homeobox genes, ceh-10, ttx-3 and ceh-23, controls cell fate specification of a defined interneuron class in C. elegans

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Synthesis and function of 3-phosphorylated inositol lipids

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Development of polarity in cerebellar granule neurons.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3210501

Expression of the PTEN tumour suppressor protein during human development

26 September 2018

1 reference

12 December 2020

Deletion of PTEN in a patient with Bannayan-Riley-Ruvalcaba syndrome suggests allelism with Cowden disease

1 reference

12 December 2020

The life cycle of the nematode Caenorhabditis elegans

1 reference

12 December 2020

The human tumour suppressor PTEN regulates longevity and dauer formation in Caenorhabditis elegans

1 reference

12 December 2020

Identifiers

DOI

10.1242/DEV.069062

1 reference

8 August 2017

1 reference

8 August 2017

1 reference