Thyroid-stimulating hormone decreases HMG-CoA reductase phosphorylation via AMP-activated protein kinase in the liver. (Q35536395)

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1 March 2020

title

Thyroid-stimulating hormone decreases HMG-CoA reductase phosphorylation via AMP-activated protein kinase in the liver (English)

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2

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Jiajun Zhao

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author name string

Xiujuan Zhang

1

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Mei Feng

3

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Xinli Zhou

4

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Yingli Lu

5

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Ling Gao

6

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Chunxiao Yu

7

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Xiuyun Jiang

8

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publication date

23 February 2015

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Journal of Lipid Research

1 March 2020

published in

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volume

56

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issue

5

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page(s)

963-971

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Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status

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Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase

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Replacement of serine-871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis induced by ATP depletion

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Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth

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Diurnal changes in the fraction of 3-hydroxy-3-methylglutaryl-CoA reductase in the active form in rat liver microsomal fractions

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Improved assay of 3-hydroxy-3-methylglutaryl coenzyme A reductase

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Diurnal rhythm of rat liver mRNAs encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase. Correlation of functional and total mRNA levels with enzyme activity and protein

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Inhibition of fatty acid and cholesterol synthesis by stimulation of AMP-activated protein kinase

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Hydroxymethylglutaryl-CoA reductase--the rate-limiting enzyme of cholesterol biosynthesis. A report of a meeting held at Nijenrode Castle, Breukelen, The Netherlands, August 24, 1985

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[Thyroid hormones and lipid metabolism]

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A novel role for thyroid-stimulating hormone: up-regulation of hepatic 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase expression through the cyclic adenosine monophosphate/protein kinase A/cyclic adenosine monophosphate-responsive element binding

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Regulation of hepatic cholesterol biosynthesis by berberine during hyperhomocysteinemia

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Diurnal and dietary-induced changes in cholesterol synthesis correlate with levels of mRNA for HMG-CoA reductase

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Identifiers

DOI

10.1194/JLR.M047654

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1 March 2020

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1 March 2020

PubMed publication ID

25713102

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