The melatonin MT1 receptor axis modulates mutant Huntingtin-mediated toxicity (Q35542836)

8 August 2017

title

The melatonin MT1 receptor axis modulates mutant Huntingtin-mediated toxicity (English)

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8 August 2017

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14

Robert J Ferrante

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8 August 2017

13

Bruce S Kristal

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8 August 2017

Xin Wang

1

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8 August 2017

Ana Sirianni

2

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8 August 2017

Zhijuan Pei

3

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8 August 2017

Kerry Cormier

4

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8 August 2017

Karen Smith

5

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8 August 2017

Jiying Jiang

6

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8 August 2017

Shuanhu Zhou

7

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8 August 2017

Hui Wang

8

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8 August 2017

Rong Zhao

9

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8 August 2017

Hiroko Yano

10

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8 August 2017

Jeong Eun Kim

11

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8 August 2017

Wei Li

12

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8 August 2017

Robert M Friedlander

15

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8 August 2017

language of work or name

English

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publication date

1 October 2011

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8 August 2017

published in

Journal of Neuroscience

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8 August 2017

volume

31

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8 August 2017

issue

41

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8 August 2017

page(s)

14496-14507

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Genetic variation of melatonin productivity in laboratory mice under domestication

8 August 2017

cites work

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Dysregulation of receptor interacting protein-2 and caspase recruitment domain only protein mediates aberrant caspase-1 activation in Huntington's disease.

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Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease

12 July 2018

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12 July 2018

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12 July 2018

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Distribution of melatonin MT1 receptor immunoreactivity in human retina

12 July 2018

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Malondialdehyde, superoxide dismutase, melatonin, iron, copper, and zinc blood concentrations in patients with Alzheimer disease: cross-sectional study

12 July 2018

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Functional expression of MT2 (Mel1b) melatonin receptors in human PAZ6 adipocytes

12 July 2018

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Huntingtin's neuroprotective activity occurs via inhibition of procaspase-9 processing

12 July 2018

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12 July 2018

Melatonin and climactery

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Alteration of caspases and apoptosis-related proteins in brains of patients with Alzheimer's disease.

12 July 2018

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The early cellular pathology of Huntington's disease

12 July 2018

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Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

12 July 2018

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Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease

12 July 2018

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Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy

12 July 2018

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Melatonin reduces quinolinic acid-induced lipid peroxidation in rat brain homogenate

12 July 2018

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12 July 2018

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A therapeutic role for melatonin antagonism in experimental models of Parkinson's disease

12 July 2018

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Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

12 July 2018

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Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

12 July 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Melatonin protects primary cultures of rat cortical neurones from NMDA excitotoxicity and hypoxia/reoxygenation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

12 July 2018

1 reference

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

12 July 2018

1 reference

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The voltage sensor of the mitochondrial permeability transition pore is tuned by the oxidation-reduction state of vicinal thiols. Increase of the gating potential by oxidants and its reversal by reducing agents.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Influence of pinealectomy on plasma and extrapineal melatonin rhythms in young chickens (Gallus domesticus).

12 July 2018

1 reference

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Decreased MT1 and MT2 melatonin receptor expression in extrapineal tissues of the rat during physiological aging

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Favorable effects of a prolonged treatment with melatonin on the level of oxidative damage and neurodegeneration in senescence-accelerated mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Global changes to the ubiquitin system in Huntington's disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Effect of exogenous melatonin on sleep and motor dysfunction in Parkinson's disease. A randomized, double blind, placebo-controlled study

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Time course of post-traumatic mitochondrial oxidative damage and dysfunction in a mouse model of focal traumatic brain injury: implications for neuroprotective therapy

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Combination therapy using minocycline and coenzyme Q10 in R6/2 transgenic Huntington's disease mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Non A beta component of Alzheimer's disease amyloid and amyloid beta peptides evoked poly(ADP-ribose) polymerase-dependent release of apoptosis-inducing factor from rat brain mitochondria

26 September 2018

1 reference

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A role of melatonin in neuroectodermal-mesodermal interactions: the hair follicle synthesizes melatonin and expresses functional melatonin receptors

26 September 2018

1 reference

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Effect of melatonin on brain oxidative damage induced by traumatic brain injury in immature rats.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Protective effect of melatonin on 3-nitropropionic acid-induced oxidative stress in synaptosomes in an animal model of Huntington's disease

26 September 2018

1 reference

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Add-on melatonin improves quality of life in epileptic children on valproate monotherapy: a randomized, double-blind, placebo-controlled trial

26 September 2018

1 reference

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Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism responsible for anti-apoptotic effects of melatonin

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Evaluation of the antiperoxidative effects of melatonin in ammonium acetate-treated Wistar rats

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Sequential activation of individual caspases, and of alterations in Bcl‐2 proapoptotic signals in a mouse model of Huntington's disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Role of CSF in the transport of melatonin

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Cytochrome C and caspase-9 expression in Huntington's disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Localization of the melatonin-related receptor in the rodent brain and peripheral tissues

26 September 2018

1 reference

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Bioavailability of oral melatonin in humans.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213696

Effect of chronic consumption of sodium valproate and melatonin on seizure activity in Krushinskii-Molodkina rats

26 September 2018

1 reference

12 December 2020

A unicenter, randomized, double-blind, parallel-group, placebo-controlled study of Melatonin as an Adjunct in patients with acute myocaRdial Infarction undergoing primary Angioplasty The Melatonin Adjunct in the acute myocaRdial Infarction treated w

1 reference

12 December 2020

The immuno-reconstituting effect of melatonin or pineal grafting and its relation to zinc pool in aging mice

1 reference

12 December 2020

Melatonin but not vitamins C and E maintains glutathione homeostasis in t-butyl hydroperoxide-induced mitochondrial oxidative stress

1 reference

12 December 2020

[Sleep disorders and the 24-hour profile of melatonin and cortisol]

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12 December 2020

10.1523/JNEUROSCI.3059-11.2011

Identifiers

DOI

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8 August 2017

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8 August 2017

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