Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells (Q35545116)

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17 November 2019

title

Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells (English)

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17 November 2019

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4

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17 November 2019

Daniel J Weisenberger

2

object named as

Daniel J Weisenberger

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17 November 2019

author name string

Jonathan C Cheng

1

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17 November 2019

Felicidad A Gonzales

3

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17 November 2019

Guo-Liang Xu

5

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17 November 2019

Ye-Guang Hu

6

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17 November 2019

Victor E Marquez

7

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17 November 2019

Peter A Jones

8

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17 November 2019

language of work or name

English

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publication date

1 February 2004

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Molecular and Cellular Biology

17 November 2019

published in

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17 November 2019

volume

24

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17 November 2019

page(s)

1270-1278

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17 November 2019

issue

3

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Epigenomic stress response. Knockdown of DNA methyltransferase 1 triggers an intra-S-phase arrest of DNA replication and induction of stress response genes

17 November 2019

cites work

1 reference

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DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells

12 July 2018

1 reference

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Zebularine: A Novel DNA Methylation Inhibitor that Forms a Covalent Complex with DNA Methyltransferases

12 July 2018

1 reference

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Worms gang up on bacteria

12 July 2018

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DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

12 July 2018

1 reference

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Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements

12 July 2018

1 reference

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Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

12 July 2018

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DNA methylation inhibitors in the treatment of leukemias, myelodysplastic syndromes and hemoglobinopathies: clinical results and possible mechanisms of action

12 July 2018

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Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells

12 July 2018

1 reference

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DNA methylation and cancer

12 July 2018

1 reference

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Whole-genome methylation scan in ICF syndrome: hypomethylation of non-satellite DNA repeats D4Z4 and NBL2.

12 July 2018

1 reference

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Low-dose 5-aza-2'-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: a multicenter phase II study in elderly patients

12 July 2018

1 reference

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Roles of cell division and gene transcription in the methylation of CpG islands.

12 July 2018

1 reference

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CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression.

12 July 2018

1 reference

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The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

12 July 2018

1 reference

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Cancer epigenetics comes of age

12 July 2018

1 reference

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Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE)

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321446

Real time quantitative PCR

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321446

Improved synthesis of zebularine [1-(beta-D-ribofuranosyl)-dihydropyrimidin-2-one] nucleotides as inhibitors of human deoxycytidylate deaminase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321446

5-Aza-2'-deoxycytidine (Decitabine) and 5-azacytidine in the treatment of acute myeloid leukemias and myelodysplastic syndromes: past, present and future trends

12 July 2018

1 reference

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Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321446

DNA methylation in 5-aza-2'-deoxycytidine-resistant variants of C3H 10T1/2 C18 cells

12 July 2018

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Cellular differentiation, cytidine analogs and DNA methylation

12 July 2018

1 reference

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Furanose-pyranose isomerization of reduced pyrimidine and cyclic urea ribosides

12 July 2018

1 reference

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Synthesis of pyrimidin-2-one nucleosides as acid-stable inhibitors of cytidine deaminase

12 July 2018

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A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands

12 July 2018

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Phenotypic conversion of cultured mouse embryo cells by aza pyrimidine nucleosides

12 July 2018

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Kinetics of phosphorylation of 5-aza-2′-deoxycytidine by deoxycytidine kinase

12 July 2018

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Isolation, characterization, and properties of a labile hydrolysis product of the antitumor nucleoside, 5-azacytidine

12 July 2018

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Functional striated muscle cells from non-myoblast precursors following 5-azacytidine treatment

12 July 2018

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DNA methyltransferase 3b contributes to oncogenic transformation induced by SV40T antigen and activated Ras.

12 July 2018

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Inhibition of DNA methylation and reactivation of silenced genes by zebularine

26 September 2018

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Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine

26 September 2018

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Cell division is required for de novo methylation of CpG islands in bladder cancer cells

26 September 2018

1 reference

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DNA methylator and mismatch repair phenotypes are not mutually exclusive in colorectal cancer cell lines

26 September 2018

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Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321446

The mechanism of inhibition of DNA (cytosine-5-)-methyltransferases by 5-azacytosine is likely to involve methyl transfer to the inhibitor

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321446

Mechanism-based inhibition of C5-cytosine DNA methyltransferases by 2-H pyrimidinone 1 1Edited by J. Karn

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=321446

Murine de novo methyltransferase Dnmt3a demonstrates strand asymmetry and site preference in the methylation of DNA in vitro

15 November 2018

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12 December 2020

Induction of thymidine kinase in enzyme-deficient chinese hamster cells

1 reference

12 December 2020

Potent inhibitors for the deamination of cytosine arabinoside and 5-aza-2'-deoxycytidine by human cytidine deaminase

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12 December 2020

Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing

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12 December 2020

The fundamental role of epigenetic events in cancer

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12 December 2020

10.1128/MCB.24.3.1270-1278.2004

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14729971%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

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17 November 2019

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