Inhibition of classical PKC isoenzymes downregulates STAT1 activation and iNOS expression in LPS-treated murine J774 macrophages. (Q35545779)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16432499%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Inhibition of classical PKC isoenzymes downregulates STAT1 activation and iNOS expression in LPS-treated murine J774 macrophages (English)

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15 January 2020

2

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15 January 2020

Hannu Kankaanranta

4

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15 January 2020

author name string

Tiina Salonen

1

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15 January 2020

Ulla Jalonen

3

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15 January 2020

Raimo Tuominen

5

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15 January 2020

Eeva Moilanen

6

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15 January 2020

language of work or name

English

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publication date

1 April 2006

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British Journal of Pharmacology

15 January 2020

published in

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15 January 2020

volume

147

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15 January 2020

issue

7

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15 January 2020

page(s)

790-799

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Nitric oxide production and signaling in inflammation.

15 January 2020

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Protein kinase C-eta (PKC-eta) is required for the development of inducible nitric oxide synthase (iNOS) positive phenotype in human monocytic cells

12 July 2018

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Regulation of the expression of inducible nitric oxide synthase.

12 July 2018

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Regulation of JAK-STAT signalling in the immune system

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Protein kinase C epsilon: a new target to control inflammation and immune-mediated disorders

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P38 mitogen-activated protein kinase inhibitor SB203580 has a bi-directional effect on iNOS expression and NO production

12 July 2018

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Protein kinase Cepsilon is required for macrophage activation and defense against bacterial infection

12 July 2018

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Lipopolysaccharide-induced expression of interferon-beta mediates the timing of inducible nitric-oxide synthase induction in RAW 264.7 macrophages

12 July 2018

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Opposing cardioprotective actions and parallel hypertrophic effects of delta PKC and epsilon PKC.

12 July 2018

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Identification of protein kinase C isoforms involved in interferon-gamma-induced expression of inducible nitric oxide synthase in murine BV2 microglia

12 July 2018

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Protein kinase Cdelta activation by interleukin-1beta stabilizes inducible nitric-oxide synthase mRNA in pancreatic beta-cells

12 July 2018

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Cyclooxygenase-2 expression in macrophages: modulation by protein kinase C-alpha

12 July 2018

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

12 July 2018

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Induction of COX-2 and PGE(2) biosynthesis by IL-1beta is mediated by PKC and mitogen-activated protein kinases in murine astrocytes

12 July 2018

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Identification of PKC-isoform-specific biological actions using pharmacological approaches

12 July 2018

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Antisense oligonucleotides targeting protein kinase C-alpha, -beta I, or -delta but not -eta inhibit lipopolysaccharide-induced nitric oxide synthase expression in RAW 264.7 macrophages: involvement of a nuclear factor kappa B-dependent mechanism.

12 July 2018

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Protein kinase C-alpha modulates lipopolysaccharide-induced functions in a murine macrophage cell line

12 July 2018

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Pyrimidinoceptor-mediated potentiation of inducible nitric-oxide synthase induction in J774 macrophages. Role of intracellular calcium.

12 July 2018

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Protein kinase C eta mediates lipopolysaccharide-induced nitric-oxide synthase expression in primary astrocytes

12 July 2018

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Nitric oxide and macrophage function

12 July 2018

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Differential regulation by protein kinase C isoforms of nitric oxide synthase induction in RAW 264.7 macrophages and rat aortic smooth muscle cells

12 July 2018

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Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976.

12 July 2018

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12 July 2018

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12 July 2018

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Properties of protein kinase C isoforms (beta II, epsilon, and zeta) in a macrophage cell line (J774) and their roles in LPS-induced nitric oxide production.

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Conventional protein kinase C and atypical protein kinase Czeta differentially regulate macrophage production of tumour necrosis factor-alpha and interleukin-10.

12 July 2018

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c-Jun NH2-terminal kinase inhibitor anthra(1,9-cd)pyrazol-6(2H)-one reduces inducible nitric-oxide synthase expression by destabilizing mRNA in activated macrophages

26 September 2018

1 reference

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(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta

26 September 2018

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The delta-isoform of protein kinase C causes inducible nitric-oxide synthase and nitric oxide up-regulation: key mechanism for oxidant-induced carbonylation, nitration, and disassembly of the microtubule cytoskeleton and hyperpermeability of barrier

26 September 2018

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12 December 2020

Differential down-regulation of protein kinase C isozymes

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12 December 2020

Inhibitors of protein kinase C. 1. 2,3-bisarylmaleimides

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12 December 2020

New hexahydroxybiphenyl derivatives as inhibitors of protein kinase C

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12 December 2020

The sevenfold way of PKC regulation

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12 December 2020

Autocrine/paracrine IFN-alphabeta mediates the lipopolysaccharide-induced activation of transcription factor Stat1alpha in mouse macrophages: pivotal role of Stat1alpha in induction of the inducible nitric oxide synthase gene

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12 December 2020

Increased protein kinase C activity and expression of Ca2+-sensitive isoforms in the failing human heart

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12 December 2020

Protein kinase C mediates lipopolysaccharide- and phorbol-induced nitric-oxide synthase activity and cellular injury in the rat colon

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12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0706672

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16432499%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

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15 January 2020

PubMed publication ID

16432499

1 reference