Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury (Q35546843)

8 August 2017

1 reference

title

Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury (English)

1 reference

8 August 2017

1 reference

1 reference

Hartmut Jaeschke

1

1 reference

8 August 2017

John J. Lemasters

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14517806

15 March 2024

language of work or name

English

0 references

publication date

1 October 2003

1 reference

full work available at URL

8 August 2017

https://cdr.lib.unc.edu/downloads/1544bz502

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14517806

https://api.elsevier.com/content/article/PII:S0016508503012095?httpAccept=text/xml

15 March 2024

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(03)01209-5

https://api.elsevier.com/content/article/PII:S0016508503012095?httpAccept=text/plain

15 March 2024

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(03)01209-5

15 March 2024

1 reference

8 August 2017

125

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8 August 2017

1246-1257

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8 August 2017

4

1 reference

Mechanisms of reperfusion injury after warm ischemia of the liver

8 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Preservation injury of the liver: mechanisms and novel therapeutic strategies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Role of microcirculation in transplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Reperfusion injury to endothelial cells following cold ischemic storage of rat livers.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

The mitochondrial permeability transition and the calcium, oxygen and pH paradoxes: one paradox after another

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Superoxide Generation by Kupffer Cells and Priming of Neutrophils During Reperfusion After Hepatic Ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Role of cytokines and cytokine-producing cells in reperfusion injury to the liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Functional inactivation of neutrophils with a Mac-1 (CD11b/CD18) monoclonal antibody protects against ischemia-reperfusion injury in rat liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

In vitro toxicity of polymorphonuclear neutrophils to rat hepatocytes: evidence for a proteinase-mediated mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Role of endothelins and nitric oxide in hepatic reperfusion injury in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Reperfusion injury induces apoptosis in rabbit cardiomyocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Apoptosis of sinusoidal endothelial cells is a critical mechanism of preservation injury in rat liver transplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Blebbing, free Ca2+ and mitochondrial membrane potential preceding cell death in hepatocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Calcium dependence of bleb formation and cell death in hepatocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Glycine blocks opening of a death channel in cultured hepatic sinusoidal endothelial cells during chemical hypoxia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Distinct alterations in mitochondrial mass and function characterize different models of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Lethal effect of the anti-Fas antibody in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Pathophysiology of mitochondrial cell death control.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

BCL-2 family members and the mitochondria in apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Caspases: the executioners of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Two CD95 (APO-1/Fas) signaling pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Bid, a critical mediator for apoptosis induced by the activation of Fas/TNF-R1 death receptors in hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Mitochondrial transport of cations: channels, exchangers, and permeability transition.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

The Mitochondrial Permeability Transition Augments Fas-induced Apoptosis in Mouse Hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Apoptosis: overview and signal transduction pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

TNF-R1 signaling: a beautiful pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Analysis of apoptosis by laser scanning cytometry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Early loss of large genomic DNA in vivo with accumulation of Ca2+ in the nucleus during acetaminophen-induced liver injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: effects of Ca(2+)-endonuclease, DNA repair, and glutathione depletion inhibitors on DNA fragmentation and cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

"Apoptotic" myocytes in infarct area in rabbit hearts may be oncotic myocytes with DNA fragmentation: analysis by immunogold electron microscopy combined with In situ nick end-labeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Mode of cell death after acetaminophen overdose in mice: apoptosis or oncotic necrosis?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Mechanisms underlying hypoxia-induced neuronal apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Cell biology and molecular mechanisms of injury in ischemic acute renal failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Apoptosis after ischemia-reperfusion in human liver allografts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Endothelial cell and hepatocyte deaths occur by apoptosis after ischemia-reperfusion injury in the rat liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

A caspase inhibitor fully protects rats against lethal normothermic liver ischemia by inhibition of liver apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Apoptosis of sinusoidal endothelial cells occurs during liver preservation injury by a caspase-dependent mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Platelets induce sinusoidal endothelial cell apoptosis upon reperfusion of the cold ischemic rat liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Synergism between platelets and leukocytes in inducing endothelial cell apoptosis in the cold ischemic rat liver: a Kupffer cell-mediated injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: apoptosis or necrosis?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Extended preservation of rat liver graft by induction of heme oxygenase-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Impact of prolonged cold ischemia and reperfusion on apoptosis, activation of caspase 3, and expression of bax after liver transplantation in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Protection against Fas receptor-mediated apoptosis in hepatocytes and nonparenchymal cells by a caspase-8 inhibitor in vivo: evidence for a postmitochondrial processing of caspase-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Differential protection with inhibitors of caspase-8 and caspase-3 in murine models of tumor necrosis factor and Fas receptor-mediated hepatocellular apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Inhibition of Fas receptor (CD95)-induced hepatic caspase activation and apoptosis by acetaminophen in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Oncotic necrosis and caspase-dependent apoptosis during galactosamine-induced liver injury in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Reduction of ischemia-reperfusion injury of the liver by in vivo adenovirus-mediated gene transfer of the antiapoptotic Bcl-2 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Bcl–2 protects from lethal hepatic apoptosis induced by an ant–Fas antibody in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Prevention of hypoxic liver cell necrosis by in vivo human bcl-2 gene transfection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Expression of bcl-2 inhibits necrotic neural cell death.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Enhanced acetaminophen hepatotoxicity in transgenic mice overexpressing BCL-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Acetaminophen-induced inhibition of Fas receptor-mediated liver cell apoptosis: mitochondrial dysfunction versus glutathione depletion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Interleukin-1beta converting enzyme (caspase-1) in intestinal inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Inflammation in response to hepatocellular apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Parenchymal cell apoptosis as a signal for sinusoidal sequestration and transendothelial migration of neutrophils in murine models of endotoxin and Fas-antibody-induced liver injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kappa B-independent, caspase-3-dependent pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Intracellular pH during "chemical hypoxia" in cultured rat hepatocytes. Protection by intracellular acidosis against the onset of cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Intracellular pH and Ca2+ homeostasis in the pH paradox of reperfusion injury to neonatal rat cardiac myocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

ATP depletion rather than mitochondrial depolarization mediates hepatocyte killing after metabolic inhibition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Recovery of hepatocellular ATP and "pericentral apoptosis" after hemorrhage and resuscitation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Control of apoptosis by the cellular ATP level

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Aponecrosis: morphological and biochemical exploration of a syncretic process of cell death sharing apoptosis and necrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

The mitochondrial permeability transition initiates autophagy in rat hepatocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

Differential role of I kappa B kinase 1 and 2 in primary rat hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

inferred from DOI database lookup

7 January 2021

based on heuristic

Protection by acidotic pH against anoxic cell killing in perfused rat liver: evidence for a pH paradox.

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

inferred from DOI database lookup

7 January 2021

based on heuristic

Activation of Kupffer cells and neutrophils for reactive oxygen formation is responsible for endotoxin-enhanced liver injury after hepatic ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901209-5

inferred from DOI database lookup

7 January 2021

based on heuristic

Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning

6

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(03)01209-5

Complement activates Kupffer cells and neutrophils during reperfusion after hepatic ischemia

15 March 2024

15

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(03)01209-5

Superoxide generation by neutrophils and Kupffer cells during in vivo reperfusion after hepatic ischemia in rats

15 March 2024

18

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(03)01209-5

Activation of apoptosis during the reperfusion phase after rat liver ischemia

15 March 2024

24

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(03)01209-5

Studies of necrosis in vitro of mouse hepatic parenchymal cells. Ultrastructural alterations in endoplasmic reticulum, Golgi apparatus, plasma membrane, and lipid droplets

15 March 2024

26

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https://api.crossref.org/works/10.1016/S0016-5085(03)01209-5

Apoptosis, oncosis, and necrosis. An overview of cell death

15 March 2024

31

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https://api.crossref.org/works/10.1016/S0016-5085(03)01209-5

The expanding role of mitochondria in apoptosis

15 March 2024

49

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https://api.crossref.org/works/10.1016/S0016-5085(03)01209-5

Internucleosomal DNA cleavage triggered by plasma membrane damage during necrotic cell death. Involvement of serine but not cysteine proteases

15 March 2024

56

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(03)01209-5

Mac-1 (CD11b/CD18) and intercellular adhesion molecule-1 in ischemia-reperfusion injury of rat liver

15 March 2024

94

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https://api.crossref.org/works/10.1016/S0016-5085(03)01209-5

Fructose prevents hypoxic cell death in liver

15 March 2024

98

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15 March 2024

Identifiers

1 reference

8 August 2017

1 reference