The Mitochondrial Permeability Transition Augments Fas-induced Apoptosis in Mouse Hepatocytes (Q57232496)

6

0 references

author name string

Etsuro Hatano

1

0 references

Cynthia A. Bradham

2

0 references

Yuji Iimuro

4

0 references

John J. Lemasters

Journal of Biological Chemistry

5

0 references

language of work or name

English

0 references

publication date

14 April 2000

0 references

published in

0 references

volume

275

0 references

issue

16

0 references

page(s)

11814-11823

0 references

cites work

Apoptosis by death factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Lethal effect of the anti-Fas antibody in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

CD95-induced apoptosis in human liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Tumor necrosis factor (TNF) receptor 1 signaling downstream of TNF receptor-associated factor 2. Nuclear factor kappaB (NFkappaB)-inducing kinase requirement for activation of activating protein 1 and NFkappaB but not of c-Jun N-terminal kinase/stre

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

IKAP is a scaffold protein of the IkappaB kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

The CD95 (APO-1/Fas) receptor activates NF-kappaB independently of its cytotoxic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Multiple pathways of Fas-induced apoptosis in primary culture of hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Delayed Fas-mediated hepatocyte apoptosis during liver regeneration in mice: hepatoprotective role of TNF alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Mitochondria as regulators of apoptosis: doubt no more.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Bcl-2 family proteins and mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Mitochondrial control of nuclear apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

The cytotoxicity of tumor necrosis factor depends on induction of the mitochondrial permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Bax directly induces release of cytochrome c from isolated mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Apoptotic pathways: the roads to ruin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Mitochondrial depolarization accompanies cytochrome c release during apoptosis in PC6 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

NFkappaB prevents apoptosis and liver dysfunction during liver regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Fas/APO-1(CD95)-induced apoptosis of primary hepatocytes is inhibited by cAMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Mediation by NF-kappa B of cytokine induced expression of intercellular adhesion molecule 1 (ICAM-1) in an intestinal epithelial cell line, a process blocked by proteasome inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Target protease specificity of the viral serpin CrmA. Analysis of five caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Bcl-2 activates the transcription factor NFkappaB through the degradation of the cytoplasmic inhibitor IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

S-nitrosylation regulates apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

The role of ceramide in cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Lipid signaling in CD95-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Ceramide induces caspase-independent apoptosis in rat hepatocytes sensitized by inhibition of RNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Requirement for GD3 ganglioside in CD95- and ceramide-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Commitment to apoptosis by GD3 ganglioside depends on opening of the mitochondrial permeability transition pore.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Fas and tumor necrosis factor receptor-mediated cell death: similarities and distinctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Mitochondrial control of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11814